Marcin Szczot
@szczotml.bsky.social
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pinned post!
Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8
www.biorxiv.org/content/10.6...
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Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling
Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....
https://www.biorxiv.org/content/10.64898/2025.12.10.693066v1
11 days ago
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Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8
www.biorxiv.org/content/10.6...
loading . . .
Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling
Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....
https://www.biorxiv.org/content/10.64898/2025.12.10.693066v1
11 days ago
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reposted by
Marcin Szczot
Patrik Ernfors
7 months ago
A read only for the DRG nerd: "Spatial organization, chromatin accessibility and gene-regulatory programs defining mouse sensory neurons".
www.nature.com/articles/s42...
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Spatial organization, chromatin accessibility and gene-regulatory programs defining mouse sensory neurons - Communications Biology
Single cell RNA-sequencing, spatial transcriptomics and chromatin analyses of sensory neurons provide insights into cell type organization of the dorsal root ganglion and the enhancer-driven co-regula...
https://www.nature.com/articles/s42003-025-08315-1
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It was a pleasure to host Ewan at our Linkรถping University LinkSense seminar series! We learned a lot about joints โ and even managed to gossip a bit about naked mole rats. Always a good time.
add a skeleton here at some point
7 months ago
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reposted by
Marcin Szczot
Ewan St. John Smith
8 months ago
Flew in late last night to visit
@szczotml.bsky.social
& co
@liu.se
- looking forward to an exciting day discussing touch & pain - early morning ๐๐ปโโ๏ธ = โ = ๐ธ๏ธ ๐งน
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Thank you Melisa, It has been a fascinating journey on an uncharted road. It is official now we have the first Lab Alumni! Little sour/sweet feeling TBH. Good luck in your new adventures.
add a skeleton here at some point
10 months ago
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reposted by
Marcin Szczot
Melisa Maidana Capitan
10 months ago
I really think one of the best things about science is the people you meet along the way. Thanks
@mbrodzki.bsky.social
,Gabriela, Leandro, Christoffer and Felipe!Especially thanks to
@szczotml.bsky.social
and Ilona,I really enjoyed all our discussions! Now, I'm very excited about what's coming next!
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