loading . . . Rieske oxygenases: Promising biocatalysts for bioremediation and synthesis Rieske oxygenases (ROs) can catalyze a wide array of oxidative transformations, encompassing hydroxylation, demethylation, carbocyclization, desaturation, N-oxygenation, CâC, CâN, and CâS bond cleavage, CâH amination, sulfoxidation, and epoxidation. This extensive reaction scope, combined with broad substrate tolerance, underscores their potential for development into promising biocatalysts. ROs have demonstrated pivotal roles in the bioremediation of environmental pollutants and offer a sustainable alternative to traditional chemical catalysts for producing value-added compounds. While previous reviews have covered their catalytic diversity, mechanisms, and engineering, this review focuses on the current applications, challenges, and future prospects of employing ROs in bioremediation and chemoenzymatic synthesis. Our goal is to provide insights that will guide the development of ROs into efficient, stable, and broadly applicable biocatalysts. http://dlvr.it/TT9gVv
