#IDSky Are antibiotics recommended for prophylaxis of neutropenia most likely induced by Azathioprine in an ANCA+vasculitis patient on hemodialysis?

#IDSky A male patient with acute hepatitis A asked me how soon after the episode he can try and have a baby with his partner. The partner is presumed uninfected at this point. What would you advise him? @bjegorovic.bsky.social @idvilchez.bsky.social @dralicehan.bsky.social @abstewardess.bsky.social

For a Nocardia cerebellar abscess, presumably completely removed via surgery, would you continue oral antibiotics? How long? Therapeutic dose or prophylactic?

Ground zero for field epidemiologists

Any idea if severe repeated episodes of hypoglycemia in a diabetic patient with ulcerative colitis could be a side effect of Vedolizumab? #ulcerativecolitis #vedolizumab #Entyvio #diabetes

I'm wondering about the mechanism(s) that could explain increasing fibrin monomers, but decreasing D dimers in an upper respiratory-type post-infectious syndrome. No radiological sign of thrombosis, CRP decreasing #IDSky #haematology #SARS-CoV-2 #COVID

I've been seeing a couple of (likely bacterial) pneumonias with very high D dimers. No identifiable major thrombus, no response to antiX anticoagulants, but responsive to corticosteroids. Mechanism? #haematology #IDSky

#IDSky intestinal decontamination for treatment and prevention of MDR infections in immunosuppressed, heavily pretreated patients. I feel like that is the last resort. What is your experience with this? What protocols do you use for CRE, ESBL and VRE? @bjegorovic.bsky.social @idvilchez.bsky.social

Back in 1975 I was taught to first check a urine Na and K. If the urine K was greater than Na - start spironalactone at 100 and recheck. Until the urine Na was greater than the urine K, increase the spironalactone. Once urine Na > K, then start 40 mg furosemide each day. I still use this model.

Please give it a go advance mode . Here the 🔗 and it’s still working in safari & google chrome 🇬🇧 pubmed.ncbi.nlm.nih.gov

EuropePMC relies on a feed (feeds ?) from PubMed. As I understand, it can run on its own, but I do not know how it will get updated and synchronised with PubMed. Though it does collect some data separately. I hope EuropePMC had prepared as much as they could for this predictable event.

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

#IDSky Would you use rectal swab results to guide empiric tx in an acute leukemia pt whose CRP is increasing without any signs or symptoms of active infection? Procalcitonin normal/slightly elevated. Any guidance and clinical experience is appreciated. This is a recurrent and frustrating consult rq

How a WHO Staff Member Turned the US Withdrawal into an Act of Solidarity who.foundation/blogs-post/h...

What if we proved @WHO still matters? WHO isn't perfect, but it's essential when it comes to global health. Join me in showing that health truly is for all by donating 👉 whofoundation.donorsupport.co/page/FUNEKRB... #1dollar1world #HealthForAll whofoundation.donorsupport.co/page/FUNEKRB...

#MedSky🧪 #IDSky #Neurosky Besides #Neurocovid related sequelas , patients who recovered from #COVID19 also often developed cardiovascular implications . The most prevalent abnormalities observed included myocardial inflammation, arrhythmia, tachycardia, bradycardia, and atrioventricular block …

#ImmunoSky #immunology Could a seemingly healthy person taking short-term dexamethasone experience a significant drop in CD4 (221/mmc), CD8 (108) and NK cells (79)? (Dexa 16 mg x 7 days, then 8 mg x 5 days, then lymphocyte subpop were measured)

Ciprofloxacin for S.aureus osteoarticular infections (in combination with another agent). Yes or preferably use Levo or Moxi? The Sanford guide does not have MSSA or MRSA in the spectrum of Cipro. @cortes-penfield.bsky.social @tai-md.com

#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 In this #BMJ article we update the clinical practice approach to adult fever of unknown origin #FUO! bmj.com/cgi/content/...

#IDSky Do you think a S.epidermidis isolate resistant to Doxy (MIC>1) and sensitive to Tige (MIC 0.5) will be susceptible to Mino? Isolate is from a knee sonicated prosthesis @wwrighid.bsky.social @cortes-penfield.bsky.social @idvilchez.bsky.social

#IDSky 4 ring-enhancing lesions in a lenticular ganglion in an immunocompetent host. No apparent primary tumour somewhere else, albeit on native CT. 2 dogs. Recent dental work, but not major. No foreign travel. Sudden onset of focal neurological deficit, no fever, no weight loss. Etiology?

#IDSky Do you use antibiotics to prophylax in case of variceal bleeding? The Sanford Guide says yes, Cochrane metaanalyses say yes, some large retrospective studies published recently say no(so people are trying to change the paradigm). I just realized I've never done it. What is your practice?

The genetic architecture of infectious diseases, by Dr Jean-Laurent Casanova. Fascinating historical references to a few ID titans, building up to modern genetics underlying predisposition and resistance to infections pmc.ncbi.nlm.nih.gov/articles/PMC...

#IDSky Would you do an LP on an HIV+ person who presents with secondary syphilis rash, positive VDRL and really high TPPA (over 1/40000)? No neurological symptoms.

Derangements in hemostasis can affect any organ system. But no other organ system has more effects on hemostasis than the liver. Liver dysfunction (LD) can result in deranged hemostasis with wide ranging implications. A #skeetorial. #liversky #hemesky 1/n

#MedSky #IDSky #ImmunoSky #NeuroSky A Fascinating pathophysiology of our skull bone marrow be …

Hey #IDsky #MedSky 👋 Do you know your Evans-based Medicine Rules ? You can now learn them with @skepticaliddoc.bsky.social on 🦋! Welcome 🤗

#MedSky🧪 #IDsky #Immunosky #Mucosalimmunity overview of antiviral immune responses in the oral cavity in common viral infections & their manifestations in the oral mucosa. www.nature.com/articles/s41...

#IDSky #ImmunoSky Can the combination of rituximab and ibrutinib completely inhibit CRP and procalcitonin synthesis in the context of an infection? (a concrete example of SSTI at the site of hemodialysis CVC access)?