Do patients with brief #AtrialFibrillation have reduced left atrial function? A recent study suggests they're linked. Find out more about LA performance in these patients. onlinelibrary.wiley.com/doi/10.1002/...

Study suggests safe single-stage surgery for HD in younger kids if aganglionic length is <52 cm. What factors influence surgical outcomes? Knowledge could reduce complications in infants! #Pediatrics #Surgery #Aganglionosis #Hirschsprung www.jpedsurg.org/article/S002...

How do coatings affect implant efficacy? A study found electro-sprayed poly lactic acid-dexamethasone coatings release drugs more effectively than spin-coated, enhancing biocompatibility. #BiomedicalEngineering #DrugDelivery #Implants link.springer.com/article/10.1...

How do different coronary interventions affect patients' quality of life? Research shows #CABG offers significant improvements despite higher costs vs. #PCI & MT. #Cardiology #QoL #ACS #Cost www.valuehealthregionalissues.com/article/S221...

Incidental #MediastinalMass detected by #TEE in severe #MitralStenosis pt. #CT revealed rapid growth & necrotic lymphadenopathy (possible lymphoma). Key message: TEE operators must detect & interpret mediastinal masses! #Echocardiography onlinelibrary.wiley.com/doi/10.1002/...

A study found supervised tilt training and aerobic exercises reduced recurrence of #VasovagalSyncope . Can exercise be a game changer for #HeartHealth ? Results of physical training show promise! onlinelibrary.wiley.com/doi/10.1111/...

Research suggests #curcuminoids may improve health in #TBI patients. Can they bolster recovery in the ICU? A study found promising results on inflammatory and nutritional responses. www.rimpacts.com/rd/p?c=10018... doi.org/10.1007/s402...

Does #obstructive #SleepApnea affect coronary artery disease severity? Findings show no significant differences in artery involvement based on OSA risk, raising questions about their connection. #HeartHealth #Angiography #CAD journals.lww.com/ijom/fulltex...

New review examines miRNA–14-3-3 protein interactions in tumor progression. These conserved proteins show strong potential as prognostic biomarkers and therapeutic targets in cancer. #miRNA #14-3-3 #TumorBiomarkers #metastasis onlinelibrary.wiley.com/doi/10.1002/...

Parental consanguineous marriage associated with higher #CAD prevalence (+3.2pp) and 2.4 years earlier onset. Severity unchanged. Relevant for cardiovascular risk assessment in high-consanguinity regions. #Angiography #Consanguinity www.kjfm.or.kr/journal/view...

Circulating #lncRNAs show moderate correlation with #IschemicStroke severity (NIHSS r=0.52) and prognosis (mRS r=0.49), plus mortality prediction (OR=1.55). Promising biomarkers, but more validation needed. #Stroke #Prognosis onlinelibrary.wiley.com/doi/10.1002/...

Network #MetaAnalysis in Heart Failure Reviews: #MRAs vs adverse CV events (25 studies, 54,964 pts). #Eplerenone most effective overall (HR 0.75); #spironolactone best in HF (HR 0.70). All beneficial! #HeartFailure link.springer.com/article/10.1...

Circulating tumor cells captured via #LiquidBiopsy are powerful tools for tracking metastasis and treatment response in solid tumors. This review highlights their clinical value in breast, prostate and lung cancers and their future role in #PrecisionOncology. #CTCs link.springer.com/article/10.1...

#Dapagliflozin reduces epicardial fat, myocardial fibrosis & LV mass in stage B HF patients. Key insights on #SGLT2i effects in subclinical #HeartFailure. link.springer.com/article/10.1...

ASOs & siRNA for amyloidosis, CRISPR for genetic correction, improved ERT for Fabry disease, plus immunomodulatory approaches. Challenges in drug delivery persist, but progress is real. #GeneTherapy #PrecisionMedicine #mucopolysaccharidoses #CardiacAmyloidosis www.eurekaselect.com/article/153414

#MAPLE-HCM: #Aficamten monotherapy outperformed metoprolol in symptomatic oHCM (+1.1 vs −1.2 mL/kg/min peak VO₂). Results support myosin inhibitors as first-line therapy. #ObstructiveHCM link.springer.com/article/10.1...

#MetaAnalysis: #Ticagrelor #DAPT post-PCI in CCS ↓ MACE, mortality & revasc vs clopidogrel but ↑ minor bleeding. Strongest in Ticagrelor & Asian cohorts. Personalized therapy key. #PCI @ashkanabdollahi.bsky.social @bakhshihooman.bsky.social link.springer.com/article/10.1...

In a rat #CKD model, #HIIT and aerobic training alleviate cardiac pathology, apoptosis, and atrial fibrillation by restoring #FGF23 and Klotho balance. Exercise shows promise as adjunct therapy for cardio-renal issues. #AerobicExercise www.mdpi.com/2218-273X/16...

CTI—a combined marker of #inflammation and #insulin resistance—shows strong predictive value for mortality in #MASLD. Notably, risk escalates beyond a critical threshold (~8.8). A promising tool for early risk stratification. @adrianvhernandez.bsky.social link.springer.com/article/10.1...

#HoFH progresses aggressively—even with treatment. Missed follow-up can cost lives. #PreventiveCardiology #ASCVD onlinelibrary.wiley.com/doi/10.1002/...

Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990-2023: a Global Burden of Disease Study ->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai

Rational Design of NIR-Responsive, Disulfide-Modified Bio-MOF with Antibacterial and Osteogenic Activity http://dx.doi.org/10.1021/acsabm.5c02295

#MetaAnalysis: #psoriasis is associated with lower blood #BDNF levels, supporting a neuro-immune component in disease pathophysiology and comorbidity risk. #Neuroscience #Immunology link.springer.com/article/10.1...

ML models for stroke risk prediction in AF show no significant advantage over CHA₂DS₂-VASc (AUROC 0.66 vs 0.64). Lack of external validation and heterogeneity remain key limitations. #AtrialFibrillation #Stroke #MachineLearning link.springer.com/article/10.1...

A poor diet remains a leading contributor to ischaemic heart disease, according to an analysis published in Nature Medicine. The authors estimate that suboptimal diet was responsible for more than 4 million ischaemic heart disease related deaths in 2023. go.nature.com/4m5rfbi #medsky 🧪

Chronic respiratory diseases impacted by COVID-19; mortality rates fell globally, but incidence crept up, demanding urgent global response. by Oh J, Kim S (...) Yon DK et 5 al. in Nat Med #MedSky 👉 get more here 📖 read the article:

Despite clear target engagement, #mavacamten failed to improve functional capacity or #QoL at 48 weeks. A reminder that biomarker and imaging gains don’t always translate into clinical benefit. #Cardiology #HCM #ClinicalTrials link.springer.com/article/10.1...

Persian #Syncope Functional Status Questionnaire now validated! Our study confirms strong reliability (α=0.84) and validity (CVI 92%) for assessing #QoL in Iranian patients with #VasovagalSyncope. ijms.sums.ac.ir/article_5149...

New iatrogenic complication after #MVR: LCX aneurysm fistulizing into coronary sinus. Dyspnea resolved after redo valve surgery + ligation. Rare but must be on post-op echo differential. #CardiacSurgery #CoronaryFistula academic.oup.com/ehjcr/articl...

Smaller circular staplers in #esophagojejunostomy don't harm postoperative #QoL. Anastomotic lumen diameter didn't correlate with EORTC or ECOG scores. When anatomy limits size, safe to downsize. #Postoperative link.springer.com/article/10.1...

#AF drugs risk ventricular proarrhythmia. Our review explores plant-derived atrial-selective compounds. Acacetin & resveratrol derivative C1 block NaV1.5, Kv1.5 & GIRK—sparing ventricles. Promising leads for safer AF therapy. #AtrialFibrillation #DrugDiscovery link.springer.com/article/10.1...

New study evaluates the Advanced‑DiaRem score in Iranian patients after RYGB. Findings show limited predictive power for #diabetes remission (AUC 66.7%), highlighting the need for population‑specific recalibration. #BariatricSurgery #PredictiveModels link.springer.com/article/10.1...

Mortality in diabetic #NSTEMI patients raises concerns: age, COPD, and severely reduced left ventricular function heighten risks. Could symptom awareness improve outcomes? #HeartHealth #DiabetesResearch www.rimpacts.com/rd/p?c=10075... doi.org/10.1186/s430...

Looking for factors predicting heart improvement post-PVC ablation? A review suggests various elements like age and #PVC burden matter. How can we better identify patients in need? #Cardiology #HeartHealth #Radiofrequency #Prognosis www.rimpacts.com/rd/p?c=10084... doi.org/10.2174/1573...

Why is timely treatment crucial for heart attack patients? A study shows that Iran's 24/7 PCI service meets guidelines for timely care in STEMI patients but highlights the need for improvement in certain groups. #HeartHealth #Cardiology www.rimpacts.com/rd/p?c=10084... doi.org/10.1097/hpc....

Are many unaware of their #hypertension? A study shows 36.5% of adults in Tehran have hypertension, but awareness and control are lacking, especially in younger men. #PublicHealth www.rimpacts.com/rd/p?c=10048... doi.org/10.5334/gh.1...

Smoker’s paradox debunked? Study (n=3087) finds no STEMI outcome edge post-PPCI. Research suggests smoking neutral after confounders. Heart truth? #MyocardialInfarction #Smoking www.rimpacts.com/rd/p?c=10013... doi.org/10.18502/fem...

Heart health via diet? Study finds high nitrate intake cuts angina odds by 29-46%—lowers atherogenic indices. #HeartHealth #Nutrition www.rimpacts.com/rd/p?c=10048... doi.org/10.1016/j.cp...

What’s normal for kids’ hearts? Meta-analysis sets 2DSTE-derived LA strain norms for pediatrics. #PediatricCardiology #2DSTE www.rimpacts.com/rd/p?c=10080... doi.org/10.1038/s415...

Neutrophil-to-lymphocyte ratio (NLR) shows moderate value in predicting #BreastCancer grade and #HER2 status — a simple, low-cost blood marker with potential for early risk stratification. #Oncology #Biomarkers #NLR link.springer.com/article/10.1...

LV sphericity by Gated SPECT & Echo correlates in HF but shows no prognostic value for 1‑year outcomes. #HeartFailure #Cardiology #Echocardiography irjnm.tums.ac.ir/article_4055...

#AI shows excellent accuracy (AUC ≈ 0.95) for diagnosing pulmonary embolism across imaging. Yet, performance drops in external validation—generalizability remains a challenge. #PulmonaryEmbolism #CTA journals.sbmu.ac.ir/aaem/index.p...

As #MRSA and antibiotic resistance deepen the global health threat, #PhageTherapy is regaining attention as a targeted, adaptable alternative. Can bacteriophages help us outsmart resistant #StaphylococcusAureus and reshape infection treatment? #Microbiology link.springer.com/article/10.1...

The Advanced-DiaRem score showed limited accuracy for predicting diabetes remission after RYGB in Iranian patients (AUC = 66.7%). Population-specific models are needed. #BariatricSurgery #DiabetesRemission #PredictiveModel link.springer.com/article/10.1...

Lower #BaseExcess (BE)—a sign of metabolic acidosis—was linked to greater coronary artery disease (CAD) severity in angiography patients. #CAD #Acidosis jcvtr.tbzmed.ac.ir/Article/jcvt....

LCBs are non-inferior to PCBs for treating coronary ISR, with similar clinical outcomes. Supports LCBs as a viable alternative. #Biolimus #MetaAnalysis #Paclitaxel #Sirolimus link.springer.com/article/10.1...

The Atherogenic Index of Plasma (AIP) shows strong links with CAD, MI, MetS, T2DM & OSA, but not with stroke, all-cause mortality, or NAFLD. AIP may be a useful, low-cost biomarker for cardiometabolic risk assessment. #Metabolism #Atherosclerosis link.springer.com/article/10.1...

Gut–heart–brain links in heart failure: microbial dysbiosis and metabolites like TMAO connect cardiac and cognitive decline, pointing to the microbiome as a new therapeutic frontier. #HeartFailure #Microbiome www.mdpi.com/2075-4426/15...

Dapagliflozin in acute heart failure: a new review from the DAPA ACT HF–TIMI 68 trial distills key lessons on decongestion, timing of initiation, and clinical outcomes in hospitalized HF patients. link.springer.com/article/10.1...

Case report: Anomalous RCA from left sinus w/ malignant interarterial course in 46yo woman → exertional ischemia → #CABG success. Key: CCTA + functional testing essential for high-risk diagnosis. Early surgery curative. #Tomography link.springer.com/article/10.1...