Cristina Llorente et al NATURE GI tract immune “gates” called goblet cell antigen passages (GAPs) need the muscarinic acetylcholine receptor M4 Alcohol silences M4 allowing bacteria to leak to the liver Repurposing M4 agonists may restore innate immunity and prevent alcoholic liver disease 🧵1/2

Lucky to be supported by a great society!

Great society. Great meeting. Can’t miss. @asipath.bsky.social

We're heading down South! #Pathobiology2026 will take place from May 16 to 19 at the Luminary Hotel & Co. Caloosa Sound Convention Center in Fort Myers, FL! Mark your calendar—more information will be available soon

Exciting study assessing the infant gut microbiome in the US! Early life shifts could be a driver of non-communicable disease susceptibility. @commsbio.nature.com www.nature.com/articles/s42...

He's right. "Nothing short of devastating" By @holdenthorp.bsky.social @science.org www.science.org/doi/10.1126/...

Looking forward to this session tomorrow morning!!! @asipath.bsky.social

First couple days of #pathobiology2025 have been great. Always appreciate the supportive and trainee forward environment of @asipath.bsky.social!!

Early-onset colorectal cancer has doubled in 20 years—why? New 𝘕𝘢𝘵𝘶𝘳𝘦 study from Díaz-Gay et al Ludmil Alexandrov lab here @UCSanDiego discovers mutational clues: Exposure to bacteria-derived colibactin leaves a genetic imprint, especially in tumors from young people and high-incidence countries

Steve Kerr wore a Harvard basketball shirt after the Warriors’ win tonight: “Yes, this is me supporting Harvard. Way to go. Way to stand up to the bully.”

We've greatly underestimated the role of the gut microbiome in fatty liver disease (MASLD). This open-access outstanding review @jclinical-invest.bsky.social is illuminating www.jci.org/articles/vie...