Rasmus Hartmann-Petersen about 2 months ago
New preprint!
Led by
@sarahgersing.bsky.social we map how 7,500+ variants in glucokinase (GCK) affect binding to GKRP and disentangle this from stability.
We now have activity, abundance, and interaction scores for 7,128 GCK variants - a resource for understanding phenotypes and glucose homeostasis.
add a skeleton here at some point