MGH Division of Infectious Diseases
@mgh-id.bsky.social
đ€ 1251
đ„ 676
đ 418
Patient-centered, innovative care. Groundbreaking basic, translational, and clinical research.
reposted by
MGH Division of Infectious Diseases
Boston Public Health Commission
2 days ago
â ïž ALERT: Your November SNAP Payments may be delayed due to the federal government shutdown. Need food? The City of Boston is here to help. Visit
boston.gov/SNAP
for updates on local resources for you and your family.
#ebt
#snap
#snapbenefits
#Boston
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SNAP Benefits Alert for November 2025
Background: What You Need to Know
https://boston.gov/SNAP
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insight.jci.org/articles/vie...
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JCI Insight - Viral reservoir characteristics in lymphoid tissues of HIV-1 elite controllers
https://insight.jci.org/articles/view/197308
5 days ago
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Pneumocystis jiroveci: still troublesome to diagnose and treat
journals.lww.com/co-infectiou...
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https://journals.lww.com/co-infectiousdiseases/abstract/2025/12000/pneumocystis_jiroveci__still_troublesome_to.4.aspx
5 days ago
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www.nejm.org/doi/10.1056/...
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Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025â2026 | NEJM
Changes in the vaccine advisory process in the United States have disrupted immunization guidance, which reinforces the need for independent evidence review to inform decisions regarding immunizati...
https://www.nejm.org/doi/10.1056/NEJMsa2514268
5 days ago
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www.nature.com/articles/s41...
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Anoxia activates CRISPRâCas immunity in the mouse intestine - Nature Microbiology
The Citrobacter rodentium CRISPRâCas system is activated by the oxygen-responsive transcriptional regulator Fnr in the anoxic environment of the mouse gut.
https://www.nature.com/articles/s41564-025-02172-8
5 days ago
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www.nature.com/articles/s41...
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Human immunodeficiency virus and antiretroviral therapies exert distinct influences across diverse gut microbiomes - Nature Microbiology
Metagenomic analysis of the gut microbiome of people with human immunodeficiency virus (HIV), from three distinct cohorts, revealed infection- and antiretroviral drug-linked alterations, which may con...
https://www.nature.com/articles/s41564-025-02157-7
5 days ago
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academic.oup.com/cid/advance-...
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Balancing Innovation in Artificial Intelligence with Practical Sepsis Definitions
Chanu Rhee, MD MPH, Michael Klompas, MD MPH; Balancing Innovation in Artificial Intelligence with Practical Sepsis Definitions, Clinical Infectious Disease
https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciaf602/8307106?redirectedFrom=fulltext&login=true
5 days ago
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www.clinicalmicrobiologyandinfection.org/article/S119...
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The changing epidemiology of invasive mold diseases in immunosuppressed patients: what, why, how?
The epidemiology of invasive mold diseases in immunocompromised hosts is evolving due to a combination of environmental and host-related factors.
https://www.clinicalmicrobiologyandinfection.org/article/S1198-743X(25)00522-1/abstract
5 days ago
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www.nature.com/articles/s41...
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Lysine-specific histone demethylase complex restricts EpsteinâBarr virus lytic reactivation - Nature Microbiology
The human host factors LSD1, CoREST and ZNF217 are important in maintaining EpsteinâBarr virus latency, and the depletion of these factors or inhibition of LSD1 can trigger EpsteinâBarr virus reactiva...
https://www.nature.com/articles/s41564-025-02165-7
5 days ago
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www.thelancet.com/journals/lan...
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Who pays and what pays off in sexual and reproductive health? A review of the cost and cost-effectiveness of interventions and implications for future funding and markets
This Series paper provides a summary of what is known about the funding, cost, and cost-effectiveness of sexual and reproductive health and rights interventions, interrogates the likely impacts of inc...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01724-6/abstract
5 days ago
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5 days ago
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5 days ago
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www.linkedin.com/posts/jodian...
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I am an Infectious Diseases physician currently practicing in Boston. I was born and raised in Jamaica, where I also completed my internal medicine training there. As such, I am very familiar with⊠| ...
I am an Infectious Diseases physician currently practicing in Boston. I was born and raised in Jamaica, where I also completed my internal medicine training there. As such, I am very familiar with the...
https://www.linkedin.com/posts/jodianpinkney_i-am-an-infectious-diseases-physician-currently-activity-7390858637336010752-zcua?utm_source=share&utm_medium=member_android&rcm=ACoAADg4ezkB5FkBpJiOzJDfkuaHtgVuEwn_CK8
6 days ago
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reposted by
MGH Division of Infectious Diseases
Office of Mayor Michelle Wu ćłćŒ
8 days ago
Tomorrow, SNAP benefits are set to expire. In Boston, if you need assistance with groceries or paying the bills, or if youâre looking to donate to our support fund with
@bostonfdn.bsky.social
, please visit
boston.gov/snap
or dial 311 to get help.
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8 days ago
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What a wonderful opportunity for our early career faculty and fellows to spend time this morning with Dr. Linda-Gail Bekker! We thank her for her inspiration and her time!
9 days ago
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www.thelancet.com/journals/lan...
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Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study
Olorofim showed efficacy and good tolerability in patients with IFD with few or no treatment options. Further studies will be needed to fully delineate the role of this new antifungal agent.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00224-5/abstract
10 days ago
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pubs.rsc.org/en/content/a...
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A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring
Effective monitoring of HIV treatment remains constrained by limited access to affordable, sensitive, and user-friendly viral load diagnostics, particularly in resource-limited settings. To address th...
https://pubs.rsc.org/en/content/articlelanding/2025/lc/d5lc00636h
10 days ago
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Safety of Antihypertensive Medication for the Management of Non-Severe Gestational Hypertension Among Pregnant Individuals in BotswanaâEmulating a Series of Target Trials
onlinelibrary.wiley.com/doi/10.1111/...
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https://onlinelibrary.wiley.com/doi/10.1111/ppe.70079
10 days ago
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www.sciencedirect.com/science/arti...
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Depression profiles and hepatitis C treatment outcomes among people who inject drugs: The HERO study
Evidence suggests that depression profiles may be differentially associated with healthcare engagement. Relying solely on total scores may limit our uâŠ
https://www.sciencedirect.com/science/article/pii/S0022399925003812?via%3Dihub
10 days ago
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journals.lww.com/jaids/abstra...
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https://journals.lww.com/jaids/abstract/9900/doravirine_resistance_patterns_identified_through.734.aspx
10 days ago
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jamanetwork.com/journals/jam...
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Syndromic Analysis of Sepsis Cohorts Using Large Language Models
This cohort study compares the performance of a large language model against manual medical record review for extracting presenting signs and symptoms data from hospital admission notes and uses these...
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840524
10 days ago
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www.amjmedsci.org/article/S000...
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Update on Influenza
Influenza continues to challenge global health systems due to its evolving clinical and epidemiological features, with significant morbidity and mortality worldwide. Vaccine development remains a corn...
https://www.amjmedsci.org/article/S0002-9629(25)01245-5/abstract
10 days ago
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sti.bmj.com/content/earl...
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Is screening and treating asymptomatic chlamydia and gonorrhoea among pregnant women cost-effective to prevent preterm birth and low birth weight in Botswana?
Objectives We investigated the costs and cost-effectiveness of screening and treatment for Chlamydia trachomatis and Neisseria gonorrhoeae among asymptomatic pregnant women in Botswana to prevent pret...
https://sti.bmj.com/content/early/2025/10/23/sextrans-2025-056488
10 days ago
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www.nature.com/articles/s41...
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Acute SARS-CoV-2 infection - Nature Reviews Disease Primers
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the respiratory pathogen that caused the coronavirus disease 2019 (COVID-19) pandemic. In this Primer, Sherman et al. focus on the acute...
https://www.nature.com/articles/s41572-025-00662-x
10 days ago
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11 days ago
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reposted by
MGH Division of Infectious Diseases
11 days ago
đą "#HIV coinfection increases
#HBV-induced
hepatic fibrosis through a HIF-1α-dependent pathway" on Nov-7 (8 am US ET) Wenyu Lin, PhD
@mgh-id.bsky.social
@harvardepi.bsky.social
@hsph.harvard.edu
@harvardmed.bsky.social
@ragoninstitute.bsky.social
đNo RSVP required! Info @
mailchi.mp/175bb3d515db...
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11 days ago
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Shout out to our amazing ID pharmacists as we round out National Pharmacy Week! đ€©
14 days ago
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Congratulations Erica Shenoy, MD, PhD!
15 days ago
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đCongratulations to Marlene Durand, MD, who was awarded the Watanakunakorn Clinician Award at
#IDWeek2025
this morning! đ€©
18 days ago
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reposted by
MGH Division of Infectious Diseases
Frances Ue, MD MPH
20 days ago
đŁ Come join us tomorrow as we discuss innovative strategies to bolster the ID workforce! Moderators:
@leahyoke.bsky.social
, Molly Paras, Speakers: myself, Becky Decamillis, Keenan Ryan
@mgh-id.bsky.social
@mgb-id-fellows.bsky.social
@challiance.bsky.social
@idweek.bsky.social
#IDWeek2025
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22 days ago
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Addressing the latest breakthroughs in transplantation and xenotransplantation: what are the medical hopes and ethical challenges? Featuring Dr. Jay Fishman, Director of the Transplant Infectious Disease & Compromised Host Program at MGH
www.youtube.com/watch?v=PSSa...
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Meetup#23 - Transplantationâs New Era: Promise and Dilemma
YouTube video by Fondation Brocher
https://www.youtube.com/watch?v=PSSaDoQHJuY
22 days ago
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reposted by
MGH Division of Infectious Diseases
Boston Public Health Commission
24 days ago
Weâre offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community. Find upcoming vaccine clinics at
boston.gov/vaccine-clinics
.
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Free Vaccine Clinics in Boston
Everyone ages six months and older is encouraged to get the updated flu and COVID-19 vaccines. Pregnant parents, babies, and older adults should consult their health care professional about RSV vaccin...
https://boston.gov/vaccine-clinics
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advanced.onlinelibrary.wiley.com/doi/10.1002/...
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Automated, Deep LearningâEnabled Immunoassay Microfluidic Cartridge for Viral Pathogen Detection
VISTA, the Versatile Immunodiagnostic Smartphone-based Tool for Assessment, is a disposable, electricity-free microfluidic chip designed for immunoassay-based point-of-care diagnostic applications. U...
https://advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202500025
24 days ago
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www.sciencedirect.com/science/arti...
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Randomized trial of multi-strain Lactobacillus crispatus vaginal live biotherapeutic products after antibiotic therapy for bacterial vaginosis: study protocol for VIBRANT (vaginal lIve biotherapeutic ...
Globally, approximately 30 % of women have bacterial vaginosis (BV). Antibiotic treatment is frequently followed by recurrence, likely due to lack of âŠ
https://www.sciencedirect.com/science/article/pii/S2451865425001280?via%3Dihub
24 days ago
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www.nature.com/articles/s41...
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Tracking NF-kB activity across steady-state neutrophil maturation - Cell Death Discovery
Cell Death Discovery - Tracking NF-kB activity across steady-state neutrophil maturation
https://www.nature.com/articles/s41420-025-02737-w
24 days ago
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www.sciencedirect.com/science/arti...
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Outcomes of respiratory syncytial virus infection in patients with systemic autoimmune rheumatic disease
Respiratory syncytial virus (RSV) is a common respiratory viral illness which can cause severe outcomes in older and immunosuppressed populations. TheâŠ
https://www.sciencedirect.com/science/article/abs/pii/S0049017225002173?via%3Dihub
24 days ago
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reposted by
MGH Division of Infectious Diseases
Boston Public Health Commission
25 days ago
Get the facts on who should be vaccinated for COVID-19 and the flu. Weâre following state guidance to ensure Bostonians are safe and healthy this season. Find free vaccine clinics in Boston at
boston.gov/vaccine-clinics
. Questions? Weâre here for you. Call the Mayorâs Health Line at 617-534-5050.
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29 days ago
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reposted by
MGH Division of Infectious Diseases
Madhu Pai, MD, PhD
about 1 month ago
In Paul Farmerâs Beautiful Garden of Global Health Equity: Reflections on the Third Remembrance of His Passing "Paulâs garden was never meant to be his alone. It is ours now to protect, nurture, and expand"
www.nejm.org/doi/full/10....
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In Paul Farmerâs Beautiful Garden of Global Health Equity: Reflections on the Third Remembrance of His Passing | NEJM
On the third anniversary of Paul Farmerâs death, Didi Bertrand Farmer reflects on his âbeautiful gardenâ â a vision of social justice in health care, with deep roots in the fertile soil of equity.
https://www.nejm.org/doi/full/10.1056/nejmg-blog00001
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link.springer.com/article/10.1...
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Strategies to Improve PrEP Adherence in People Who Use Drugs: A Systematic Review - AIDS and Behavior
People who use drugs (PWUD) face a disproportionately high risk of HIV, accounting for a considerable share of cases in the United States. Pre-exposure prophylaxis (PrEP) has been shown to be effective in preventing HIV transmission through both sexual contact and injection drug use. However, adherence is essential for real-world success. Following PRISMA guidelines, we conducted the first systematic review to examine PrEP interventions among PWUD and identify strategies to enhance adherence. Using EMBASE, PubMed, and ClinicalTrials.gov databases, we screened 1,389 abstracts, of which nine met the inclusion criteria. The nine studies analyzed demonstrated extensive heterogeneity in intervention components, program duration, adherence measures, and outcomes. Most interventions aimed to reduce out-of-pocket costs and improve medication accessibility, while nearly half incorporated digital or electronic tools. Successful interventions addressed financial and logistical barriers and were implemented in regions where PrEP had been integrated into national healthcare systems at no additional cost. Additionally, combining PrEP with opioid substitution therapy or medication for opioid use disorder was associated with higher adherence rates, ranging from 80 to 95% of participants. Behavioral interventions were underutilized, despite their potential to address psychosocial challenges. Finally, unique barriers faced by women who use drugs highlight the need for tailored, trauma-informed, and mental health support services to address gender-specific challenges. Ultimately, these studies serve as an important starting point, underscoring both the necessity of broader research and the potential effectiveness of targeted programs to achieve and maintain high PrEP adherence for this key population.
https://link.springer.com/article/10.1007/s10461-025-04876-8
about 1 month ago
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academic.oup.com/ofid/article...
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Evaluating the Efficacy of Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide Administered via Tube
Abstract. Human immunodeficiency virus (HIV) viral suppression was evaluated after receipt of crushed or dissolved bictegravir/emtricitabine/tenofovir alaf
https://academic.oup.com/ofid/article/12/10/ofaf588/8262682?login=true
about 1 month ago
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www.frontiersin.org/journals/med...
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Frontiers | Utilizing group-based models to identify adverse event patterns after an intervention
BackgroundStandard adverse event (AE) monitoring only records whether events occur after the intervention, and not whether these events vary over time.Object...
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1637091/full
about 1 month ago
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journals.asm.org/doi/10.1128/...
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The carbapenem inoculum effect provides insights into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales | mBio
Infections caused by carbapenem-resistant Enterobacterales (CRE) pose significant threats to patients and public health worldwide. Carbapenem resistance can occur through several molecular mechanisms,...
https://journals.asm.org/doi/10.1128/mbio.01540-25
about 1 month ago
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www.amjtransplant.org/article/S160...
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Emphysematous graft pancreatitis 20 years after transplant
A 51-year-old man with type 1 diabetes complicated by end-stage renal disease underwent a living-related kidney transplant (right-sided, 2001) and a deceased donor pancreas transplant with enteric exo...
https://www.amjtransplant.org/article/S1600-6135(25)00270-9/fulltext
about 1 month ago
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Caitlin Dugdale, MD, MSc: âI am taking my nights and weekends and every other spare minute I can find to devote to this project....I really believe in the importance of having an independent, unbiased group of people look at the data and present the data publicly.â
@mgh-mpec.bsky.social
add a skeleton here at some point
about 1 month ago
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reposted by
MGH Division of Infectious Diseases
Nature
about 1 month ago
Medical specialists, wary of the guidance provided by Trumpâs team, offer up their own advice independently of the government
go.nature.com/4pXiTnp
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Volunteer scientists work ânights and weekendsâ to guide vaccine advice in US
Medical specialists, wary of the guidance provided by Trumpâs team, offer up their own advice independently of the government.
https://go.nature.com/4pXiTnp
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about 1 month ago
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