Byrd, Marmorale, Buchan et al. @uarizona.bsky.social conducted a yeast genome-wide screen to identify genes affecting TDP-43 clearance in #ALS cell models. They found that #ESCRT complex genes and the #ubiquitin ligase Rsp5/NEDD4 facilitate TDP-43 endolysosomal clearance. rupress.org/jcb/article/...

Wang, L., Bu, T., Gao, S., ...., Cheng, C., Sun, F. (2025). PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins. Am J Physiol Cell Phys., 328(6):C2032-c2056 journals.physiology.org/doi/full/10....

Bohra and Mazumder @tifrhyderabad.bsky.social show that HP1 protein dynamics at #heterochromatin damage sites differentially regulate recruitment of DSB repair factors. Disruption of phosphorylation S11–S14 residues of HP1α impairs homologous recombination. rupress.org/jcb/article/... #Chromatin

A gut-brain axis for aversive interoception drives innate and anticipatory emesis in Drosophila. https://www.biorxiv.org/content/10.1101/2025.10.01.679515v1

The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social www.cell.com/developmenta...

How is developmental speed regulated ? 🪰 Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye. www.biorxiv.org/content/10.1... A big thanks to everyone involved!

You’ve heard of ubiquitination, meet deazaguanylation: Doug Wassarman in our lab discovered phage defense pathways have co-opted Q nucleobase biosynthetic enzymes to catalyze a new form of protein conjugation chemistry @science.org www.science.org/doi/10.1126/...

📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. @sreejithsanthosh.bsky.social biorxiv.org/content/10.1...

The @fly-eds.bsky.social is having its general assembly this saturday at 13:30 at #EDRC2025 , please join us to discuss our society and to find out more about @flybase.bsky.social and the current funding crisis

Super excited for the European Drosophila Research Conference 2025 in Alicante, Spain. Going to be 4 days of exciting science and lots of fun! My PhD student, Ujjayita will be giving a talk and I have a poster. Pls do drop by! 😊 #Drosophila #EDRC2025

We are looking forward to seeing you at the @edrc2025.bsky.social You can find us - On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS, - On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration - On poster sessions

@edrc2025.bsky.social almost there! Very much looking forward to meet up and listen to amazing #Drosophila research. Come by my poster (will have the jedi pin on it)

Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights

I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.

Help us build a much-needed school for the community of North-Central Nigeria. gofund.me/c38eefc7c

A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis! Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)

We only had a very minor contribution to this story with Alexis, but definitly worth a reading for those interested by patterning, precision and refinment. Nice combining of quantitative live imaging, modeling and optogenetics to dissect vein patterning dynamics www.cell.com/developmenta...

#Drosophila community - look at this amazing lineup for #InDRC2025 Registration for #InDRC2025 is now open! Visit indrc2025.in to register and submit your abstract. #genetics #devbio @flybase.bsky.social

📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities? Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader! 👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou... 📅Closing date: 10 October 2025