Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice. www.nature.com/articles/s41...

High-resolution #CryoET provides ‘compelling’ evidence for the true 3D architecture of glutamatergic synapses: a complex ‘synaptoplasm’ rather than the textbook postsynaptic density. buff.ly/hOYKjHH

Shreya @shreyac.bsky.social gave an excellent talk at this week's UKSN conference in beautiful Cambridge. bsky.app/profile/elis...

Olfaction geeks, come to Cambridge next month for a 30yrs old cross-disciplinary smell chat from philosophy to clinics to circuits 🧠👃 Headliner @dattalab.bsky.social on his lab's brand new olfactory maps study Networking lunches, fancy College dinner, student discount, plenty of coffee. Go register!

🚨 Preprint alert! 🚨 Can mice estimate the distance to an odour source? New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself. Spoiler alert: Yes, they can! Read the paper here: bit.ly/43A9tF9 Short 🧵 below

Johnston and Filippi lab walk in the Yorkshire Dales

Now in its final form, our recent work on how olfactory transduction currents help ensure sparse sensory coding. Led by a post-bac Kai Clane Belonio and a graduate student, Eyerusalem Haile, this was a group effort by the entire laboratory. www.jneurosci.org/content/45/1...

Check out our review comparing typical experimental to naturally-occurring odor concentrations. You might be surprised. www.jneurosci.org/content/45/1... Thanks to Matt and Betty for asking me to take part!

A new collaborative effort on the impacts of mutations in PDZD8: Autistic features in humans, with mice displaying impaired social recognition behaviour, social odour recognition, and metabolic changes. Well done Dr Pantiru! 🧠 🧪 rdcu.be/ebCH8

New preprint: a simple method (ADePT) for optical control and recording of activity by axially-decoupling the focal planes for widefield patterned photo-stimulation and two photon imaging. Proof-of-principle analysis of functional connectivity in the olfactory bulb. 1/7 #neuroscience

Our latest findings on social behavior circuits is out: how does the brain responds to social isolation? Terrific work by @dingliu.bsky.social et al. uncovering a circuit with similar neural architecture as physiological needs (hunger, thirst, sleep..). Detailed thread soon. rdcu.be/ebo63

Alexander Fjaeldstad and I have a new chapter in the book Smell, Taste, Eat: The Role of the Chemical Senses in Eating Behaviour, edited by @LorenzoDStafford. Lots of great insights here. From our chapter, it’s clear that smell loss and its impact on ingestion remain vastly underexplored."

Leeds becomes first Russell Group university to quit X but will stay on other platforms like Bluesky. www.researchprofessionalnews.com/rr-news-uk-u...

A nice (dendritic) tree for the #FluorescentFriday before Christmas. 🎄 Reconstructed and modeled in elifesciences.org/articles/06250

🔊Major Breakthrough Researchers from @UniklinikBonn @unibonn.bsky.social @rwth.bsky.social reveal how single neurons respond to smells, images & words! This study in @natureportfolio.bsky.social bridges the gap between animal & human olfactory research!👃 📖 www.nature.com/articles/s41...

We have a fresh new paper! The PhD project of the talented Mark Conway. A learning-induced change in the sensitivity of olfactory receptor neurons enables consistent perception of an odor. #olfaction #neuroscience www.science.org/doi/10.1126/...

New from Shiko Parnas' lab: Classical & operant learning in *Drosophila* rely on distinct neuronal pathways, challenging current paradigms! Unstoppable www.science.org/doi/10.1126/...

Pretty pericytes, Perching on a vessel, Protecting the brain An old Friday experiment for #FluorescentFriday #Olfaction #haiku

✨ We can’t wait to see everyone next week at the 2024 Festive Symposium in Leeds! It’s your chance to connect with #neuroscientists from academia, clinics, and industry as we explore 'The Resilient Brain'. Make sure you’ve got your ticket! bna.org.uk/mediacentre/...

Great blog by Bodo Stern (@hhmi.bsky.social) about the recent Clarivate decision on @elife.bsky.social’s impact factor. www.coalition-s.org/blog/how-the...

Sniffing helps animals identify smells and connect them to places and events, but noses can’t sense time or place. How do brains connect odors with internal models of the world? Our preprint suggests that the olfactory bulb participates in this connection. www.biorxiv.org/content/10.1...

We have *another* preprint! This work was led by the amazing Candida Tufo, ex-PhD student in the lab. We show that adult-born dopaminergic cells in the olfactory bulb rapidly functionally resemble their pre-existing counterparts! Have a look at the preprint here: www.biorxiv.org/content/10.1...

Collected by Mark Conway as part of our upcoming paper on perceptual constancy. Mitral and tufted cells in the olfactory bulb expressing GCaMP6 imaged in vivo