I was privileged to work closely with Meng-Chao during my early years as a junior PI at Fred Hutch. We worked on centromeric histones and chromosome dynamics. He fundamentally shaped how I think about genome organization. His mind was brilliant, his rigor uncompromising, his generosity boundless. 2/

Deeply saddened by the passing of my colleague, Prof. Meng-Chao Yao, a remarkable scientist and mentor. He left an indelible mark on all of us fortunate enough to know him. His legacy in molecular and ciliate biology will endure. Rest well, my friend. 1/ obituaries.seattletimes.com/obituary/men...

"Homologous recombination counteracts mismatch repair to promote fertility and genetic diversity" by Ting-Fang Wang (@tingfangwang.bsky.social) & Ji-Long Liao (廖吉隆) "We postulate that counter-actions of MMR and HR contribute to the post-zygotic isolation..." authors.elsevier.com/sd/article/S...

New meiosis and DNA repair paper pubmed.ncbi.nlm.nih.gov/40902007/

Also see two accompanying papers by the labs of Scott Keeney and Ming-Han Tong reporting similar findings, focusing on the SPO11-TOP6BL complex. www.nature.com/articles/s41... www.nature.com/articles/s41... And here is a nice News&views by Mendez Diaz and Corbett. www.nature.com/articles/d41...

Shared Alteration of Whole-Brain Connectivity and Olfactory Deficits in Multiple Autism Mouse Models https://www.biorxiv.org/content/10.1101/2025.02.02.636175v1

pubmed.ncbi.nlm.nih.gov/39706365/ Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes www.imb.sinica.edu.tw/ch/research/... Does “Chromosome Envelope” Exist in Addition to the Cell Membrane and Nuclear Envelope?

Shared Alteration of Whole-Brain Connectivity and Olfactory Deficits in Multiple Autism Mouse Models www.biorxiv.org/content/10.1...

A new review is just published pubmed.ncbi.nlm.nih.gov/39731919/