Cool study & thread from @krishnanyamuna.bsky.social . pH maps inside organelles- take home its NOT uniform

Applications open for the mid-term PhD program in Biology at TIFR, Mumbai! 𝗙𝗼𝗰𝘂𝘀: Cell Biology, Developmental Neuroscience & Neurogenetics 𝗪𝗵𝗲𝗿𝗲: Department of Biological Sciences (tifr.res.in/dbs/) 𝗘𝗹𝗶𝗴𝗶𝗯𝗶𝗹𝗶𝘁𝘆: JRF or GATE 𝗔𝗽𝗽𝗹𝘆: tinyurl.com/5xtm27f9 𝗗𝗲𝗮𝗱𝗹𝗶𝗻𝗲: Jan 22, 2026 #PhDinIndia

Fun hear.

Important consideration when doing imaging

Wonderful initiative linking @biorxivpreprint.bsky.social to @qedscience.bsky.social. 👍🏽👏🏽 @odedrechavi.bsky.social & @richardsever.bsky.social

Cool study

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/

super interesting-dig in

Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm

Spatial memory & motion are expressed simultaneously during behaviours. Synchronization of hippocampal dynamics (HD) occurs during movement. Disrupting HD during locomotion impairs memory. ⭐ work @rhythmicspikes.bsky.social @ncbsbangalore.bsky.social in #IAN25 Read more: tinyurl.com/4dah3xw6

🚀 #ALBADiversityWeek 2025 starts today! We celebrate diversity & intersectionality by highlighting key activities and sharing valuable resources. 👀 Stay tuned all week as we revisit achievements and launch new initiatives. Share our posts to join the #GlobalDiversityAwarenessMonth celebration. 🧵

When its meal turns toxic, the tiny worm #CElegans shuts down digestion thanks to a single protein that links its “taste” neurons to the gut.

Super interesting-dig in Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance | Science www.science.org/doi/10.1126/...

A 19-page article in the National Geographic that covers the work of @uramakri.bsky.social @ncbsbangalore.bsky.social @tifr.res.in on black tigers, mutation load and corridors for tiger migration. Important story and impactful work. 👏🏾 www.nationalgeographic.com/animals/arti...

This award aims to highlight outstanding research by active neuroscientists working in countries underrepresented in neuroscience publications and conferences. @network-alba.bsky.social @sfn.org @ibroorg.bsky.social @fens.org

Our worm lab is recovering from a mite attack. Trainees devoted hours to cleanup A mite or two or an army They are hateful and smarmy Our helpless little ones Crushed by their whirling carny Hello give up not Gather all the stock Pick, bleach, clean Burn to death a game well fought

🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio

😮 Just WOW!! Spray GFP mRNAs on plant leaves and the leaves translate this and you get glowing leaves. www.biorxiv.org/content/10.1...

Really interesting preprint on how the nervous-system modulates heat-dependent fertility. Work from @ethanewe.bsky.social from @odedrechavi.bsky.social lab. May well be relevant in a planet that is heating up.

Read today "Comparison is the thief of Joy" True that

Our dept @tifr.res.in ‬ran an MSc by research for ~25yrs. Our last batch graduated this month. Several headed to excellent PhD programs, some to jobs. Congratulations and good luck for many fun adventures. 👏🏾Sohan Seal from my lab headed for a PhD to @mpi-cbg.de. 2nd from L, row 2

😔 Doing science has taken on elements of a corporation w/ writing=one "vertical". Output of research as patents and IP seems to be another. Metrics is a temple at which we worship at. Sometimes overlooked is serendipity, small groups that meander & in this context the idea that writing is thinking.

Important.......

⭐ 🌟 image

New organ clock data support the anti-aging benefits of estrogen for postmenopausal women. Reviewed here in context with previous and other recent reports. erictopol.substack.com/p/new-anti-a...

Bummed I missed the worm meeting this year but happy Worm Show was posted on YouTube. Bravo Morris and Curtis! www.youtube.com/watch?v=HXgU...

We are looking forward to the Worm Meeting 2027 and thank Suhong Xu(Zhejiang University School of Medicine, Hangzhou, China), Kavita Babu (Indian Institute of Science, Bangalore, India), and Erik Andersen (Johns Hopkins University Baltimore, USA) for organising. #worm25

As it’s my first time joining Worm Meeting, I was excited to participate in Worm Art show as well. This year’s topic is resilience. In times of scarcity, worms gather holding one another to reach new grounds. Alone - they are fragile, together - they rise. Even the sky yields in unity. #worm25

Role of clathrin adaptor complex AP3 in secretion of dense core vesicles from the Sahu lab, NBRC. Badal from my lab has added an experiment testing the role of AP3 in secretion of neuropeptides in C. elegans.

❤️

Favorite moment of the day: "Do Genetics" -Nobel Prize Winner Gary Ruvkun #worm25

Paul Sternberg with important WormBase news #worm25

“Do you have any advice for aspiring young scientists?” “Do genetics.” *mic drop* #worm25

For #worm25, here are updated lists of 200+ researchers for the #Celegans community to easily follow: C. elegans #1 (150 full) - go.bsky.app/HP1h3nW C. elegans #2 (50+) - go.bsky.app/J7soTHG ==> Reply to this if you'd like to be added! cc: @genetics-gsa.bsky.social #CeleganSky 🪱 🧪 1/n

👌🏽

Nice study

Looking forward to working with @network-alba.bsky.social

Pleased to share our latest work by Shivani and Subodh. We show that the essential amino acid Trp is highly toxic to C. elegans. It turns out that the bacterial diet is the culprit. Bacterial metabolism of Trp to indole causes the toxicity. www.biorxiv.org/content/10.1...

NDR kinase SAX-1 controls dendrite branch-specific elimination during neuronal remodeling in C. elegans https://www.biorxiv.org/content/10.1101/2025.06.09.658633v1

This was a brilliant public talk @tifr.res.in by Nobel laureate Prof. Brian Schmidt. It was informative, simple to understand for people outside the field, funny & inspiring. You can watch a recording here. youtube.com/watch?v=awik...

Based in Mumbai? Interested in general in science. Come to the lovely @tifr.res.in campus to listen to Paul Nurse. TODAY........

'A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K+ channel protein complex at the axon initial segment' www.science.org/doi/10.1126/...

Looking forward to this fun meeting

".....but a key feature of this community became abundantly clear: Worm people tend to help one other. They readily share insights, lab processes, even worms themselves." So true. The worm community is the best.

"I was starting to think that these worms have a way of bringing out the best in humans—generosity, cooperation, and an unbridled curiosity about life." TRUE THAT

WOW!! Poems show a 65% ⬇️ in ranges of porpoise. “We used the occurrence sites in poems to map the historical distribution of the Yangtze finless porpoise. The number of grids with occurrences declined from 169 in the Tang Dynasty to just 59 in modern times.." www.cell.com/current-biol...

Interesting study and lovely movies from @lllackner.bsky.social lab

Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans. Email or DM me to find out more. Please share & repost!

Adhikary et al. show that LIN-5/GPR-1/2 complexes present at the polar and lateral regions of the cell membrane facilitate the accumulation of contractile ring components at furrow formation and stabilize them in the midbody, thus aiding in various #cytokinesis processes. rupress.org/jcb/article/...