SmithLabIRIC
@idomyownexpts.bsky.social
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Views from the own. 🇨🇦 IRIC/UdeM
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SmithLabIRIC
T. Ryan Gregory 🇨🇦
2 months ago
Scientists at Canadian institutions have long punched well above our weight despite low and stagnant funding. Spending a billion dollars on external recruitment while science here is starving is exactly what Harper got wrong about supporting research excellence in Canada.
add a skeleton here at some point
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Nice collaboration with the Abankwa lab (University of Luxembourg) on development of peptide-based PDE6D inhibitors, and congrats to our shared PhD candidate Atanasio Gómez-Mulas!
doi.org/10.1002/cbic...
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Development of a Genetically Encoded and Potent PDE6D Inhibitor
PDE6D is a trafficking chaperone of prenylated proteins. Current small molecule PDE6D inhibitors target its hydrophobic pocket, rendering them typically poorly water soluble. Herein, PDE6D binders ar...
https://doi.org/10.1002/cbic.202500739
2 months ago
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I want to highlight this review from Laura Quirion (
@jf-cotelab.bsky.social
) and Regina Strakhova (my lab) on ARF GTPases. Great read on the atypical nature of ARF/ARL small GTPase signalling, and they make it clear there is still much we don't know!
doi.org/10.3389/fmol...
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Frontiers | Unfolding ARF and ARL GTPases: from biophysics to systems-level insights
Advanced technologies to study protein biophysics, mRNA expression and protein-protein interactions at high throughput in physiological or pathological conte...
https://doi.org/10.3389/fmolb.2025.1712544
2 months ago
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love this work - super cool and nice thread explaining potential evolutionary implications
add a skeleton here at some point
4 months ago
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PhD Position – Cancer Signalling and Structural Biology Institute for Research in Immunology and Cancer (IRIC), Université de Montréal
www.linkedin.com/posts/matthe...
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Smith Lab, IRIC | Matthew Smith
PhD Position – Cancer Signalling and Structural Biology Institute for Research in Immunology and Cancer (IRIC), Université de Montréal My lab is seeking a highly motivated PhD student to join our mult...
https://www.linkedin.com/posts/matthew-smith-99167a43_smith-lab-iric-activity-7381059784277499904-raJE?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAks9_0B6UMxBHQAW2U59jS8pqOTdPMJ_rE
4 months ago
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reposted by
SmithLabIRIC
Biozentrum, University of Basel
4 months ago
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum
#University
#Basel
#Professor
#Structural
#Biology
#Biophysics
#Biological
#Imaging
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Samara Reck-Peterson
4 months ago
We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...
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Join our Faculty | Department of Biochemistry & Biophysics
Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...
https://biochem.weill.cornell.edu/join-our-faculty
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SmithLabIRIC
Alex Merz 🇺🇸🇨🇦🇺🇦
6 months ago
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.
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SmithLabIRIC
Dylan MacKay
10 months ago
Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share
docs.google.com/document/d/1...
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National Letter
Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...
https://docs.google.com/document/d/1Gz8gql8YivQjiUG57W0FEaEyE6LtbdzPxufAbP9izww/edit?usp=sharing
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Cool review on a relatively understudied posttranslational modification: oxidation. Our colleagues in the Labbé lab at IRIC have been working to figure out the function of OSGIN proteins in cytokinesis - and its nicely summarized here!
dx.doi.org/10.1080/1538...
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Leaving the mark: FMOs as an emerging class of cytokinetic regulators
Posttranslational modification of proteins plays a fundamental role in cell biology. It provides cells a means to regulate the signaling, enzymatic or structural properties of proteins without cont...
http://dx.doi.org/10.1080/15384101.2025.2485843
10 months ago
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