SmithLabIRIC
@idomyownexpts.bsky.social
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Views from the own. 🇨🇦 IRIC/UdeM
reposted by
SmithLabIRIC
T. Ryan Gregory 🇨🇦
14 days ago
Scientists at Canadian institutions have long punched well above our weight despite low and stagnant funding. Spending a billion dollars on external recruitment while science here is starving is exactly what Harper got wrong about supporting research excellence in Canada.
add a skeleton here at some point
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Nice collaboration with the Abankwa lab (University of Luxembourg) on development of peptide-based PDE6D inhibitors, and congrats to our shared PhD candidate Atanasio Gómez-Mulas!
doi.org/10.1002/cbic...
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Development of a Genetically Encoded and Potent PDE6D Inhibitor
PDE6D is a trafficking chaperone of prenylated proteins. Current small molecule PDE6D inhibitors target its hydrophobic pocket, rendering them typically poorly water soluble. Herein, PDE6D binders ar...
https://doi.org/10.1002/cbic.202500739
16 days ago
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I want to highlight this review from Laura Quirion (
@jf-cotelab.bsky.social
) and Regina Strakhova (my lab) on ARF GTPases. Great read on the atypical nature of ARF/ARL small GTPase signalling, and they make it clear there is still much we don't know!
doi.org/10.3389/fmol...
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Frontiers | Unfolding ARF and ARL GTPases: from biophysics to systems-level insights
Advanced technologies to study protein biophysics, mRNA expression and protein-protein interactions at high throughput in physiological or pathological conte...
https://doi.org/10.3389/fmolb.2025.1712544
16 days ago
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love this work - super cool and nice thread explaining potential evolutionary implications
add a skeleton here at some point
3 months ago
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PhD Position – Cancer Signalling and Structural Biology Institute for Research in Immunology and Cancer (IRIC), Université de Montréal
www.linkedin.com/posts/matthe...
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Smith Lab, IRIC | Matthew Smith
PhD Position – Cancer Signalling and Structural Biology Institute for Research in Immunology and Cancer (IRIC), Université de Montréal My lab is seeking a highly motivated PhD student to join our mult...
https://www.linkedin.com/posts/matthew-smith-99167a43_smith-lab-iric-activity-7381059784277499904-raJE?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAks9_0B6UMxBHQAW2U59jS8pqOTdPMJ_rE
3 months ago
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reposted by
SmithLabIRIC
Biozentrum, University of Basel
3 months ago
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum
#University
#Basel
#Professor
#Structural
#Biology
#Biophysics
#Biological
#Imaging
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SmithLabIRIC
Samara Reck-Peterson
3 months ago
We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...
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Join our Faculty | Department of Biochemistry & Biophysics
Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...
https://biochem.weill.cornell.edu/join-our-faculty
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SmithLabIRIC
Alex Merz 🇺🇸🇨🇦🇺🇦
4 months ago
I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.
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SmithLabIRIC
Dylan MacKay
9 months ago
Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share
docs.google.com/document/d/1...
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National Letter
Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...
https://docs.google.com/document/d/1Gz8gql8YivQjiUG57W0FEaEyE6LtbdzPxufAbP9izww/edit?usp=sharing
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Cool review on a relatively understudied posttranslational modification: oxidation. Our colleagues in the Labbé lab at IRIC have been working to figure out the function of OSGIN proteins in cytokinesis - and its nicely summarized here!
dx.doi.org/10.1080/1538...
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Leaving the mark: FMOs as an emerging class of cytokinetic regulators
Posttranslational modification of proteins plays a fundamental role in cell biology. It provides cells a means to regulate the signaling, enzymatic or structural properties of proteins without cont...
http://dx.doi.org/10.1080/15384101.2025.2485843
9 months ago
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