Tim Sandle
@timsandle.bsky.social
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Professor Tim Sandle, PhD. Pharmaceutical microbiologist and science journalist
Pharma Now × Pharmig proudly present this knowledge-packed session featuring two industry powerhouses: Professor Tim Sandle and Manish Bhatkar
www.youtube.com/watch?v=E6cJ...
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Microbiology Matters: Annex 1 & The Future of Contamination Control | Pharmig x Pharma Now
YouTube video by Pharma Now
https://www.youtube.com/watch?v=E6cJ3XPl_PE&t=160s
2 days ago
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The Science of Sweating During a Workout
www.pharmamicroresources.com/2025/09/the-...
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The Science of Sweating During a Workout
sweating and science
https://www.pharmamicroresources.com/2025/09/the-science-of-sweating-during-workout.html
4 days ago
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Microbiology/RMM In-Depth Focus 2025. This in-depth focus features articles on rapid microbiological methods, quality control, and using AI to read agar plates:
www.europeanpharmaceuticalreview.com/article/2651...
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Microbiology/RMM In-Depth Focus 2025
This in-depth focus features articles on rapid microbiological methods, quality control, and using AI to read agar plates.
https://www.europeanpharmaceuticalreview.com/article/265182/microbiology-rmm-in-depth-focus-2025/
9 days ago
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FDA Issues New Guidance For Clinical Trial Dosage Of Oncology Therapeutic Radiopharmaceuticals
www.clinicalleader.com/doc/fda-issu...
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FDA Issues New Guidance For Clinical Trial Dosage Of Oncology Therapeutic Radiopharmaceuticals
The FDA has issued a draft guidance titled Oncology Therapeutic Radiopharmaceuticals: Dosage Optimization During Clinical Development and is accepting public comments through October 20, 2025.
https://www.clinicalleader.com/doc/fda-issues-new-guidance-for-clinical-trial-dosage-of-oncology-therapeutic-radiopharmaceuticals-0001
9 days ago
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What to Know About Scientific Communication - At its core, the goal is to make complex findings accessible:
www.pharmamicroresources.com/2025/09/what...
#science
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What to Know About Scientific Communication
Science and communication
https://www.pharmamicroresources.com/2025/09/what-to-know-about-scientific.html
10 days ago
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Evaluating Pyrogen Contamination Risk and the Need for the MAT in Pharmaceutical Processing
www.researchgate.net/publication/...
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(PDF) Evaluating Pyrogen Contamination Risk and the Need for the MAT in Pharmaceutical Processing
PDF | Pyrogens are commonly divided into two classes: exogenous pyrogens, such as endotoxin from Gram-negative bacteria that induce fever when applied... | Find, read and cite all the research you nee...
https://www.researchgate.net/publication/351591034_Evaluating_Pyrogen_Contamination_Risk_and_the_Need_for_the_MAT_in_Pharmaceutical_Processing
13 days ago
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In this newsletter, Tim Sandle profiles the bacterium Stenotrophomonas maltophilia – a nosocomial emerging pathogen and a problem for healthcare and pharmaceutical water systems:
www.linkedin.com/pulse/ubiqui...
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https://www.linkedin.com/pulse/ubiquitous-narrow-malt-feeder-profiling-maltophilia-professor-tim-75mae/In
13 days ago
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Free webinar - What’s Lurking in the Water: Controlling Pharmaceutical Water Systems September 23rd 2-3pm:
register.gotowebinar.com/register/767...
13 days ago
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Microbiology Matters: Annex 1 & The Future of Contamination Control. In an interactive fireside chat, Professor Tim Sandle, PhD, one of the world’s leading voices in pharmaceutical microbiology, will share insights on what’s changing
www.pharmanow.live/pharma-event...
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Pharmig x Pharma Now Webinar | The Future of Contamination Control
Join Pharma Now, in partnership with Pharmig UK, for its first-ever webinar, joined by some of the biggest names in the microbiology industry. Register now for free!
https://www.pharmanow.live/pharma-events/pharmig-pharma-now-webinar-contamination-control
18 days ago
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This week’s article looks at some of the recent findings linked to biofilm formation in water distribution systems. This is with an emphasis on how biofilms are formed in relation to hydraulic conditions and what lessons can be drawn for system design:
www.linkedin.com/pulse/water-...
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Water microbiology: Hydraulics, plastics and biofilm development
Microorganisms in water systems will be found in one of four states: Planktonic cells, Initial surface attachment (not yet a biofilm), Biofilms, Cells, attached to loose deposits Biofilm development i...
https://www.linkedin.com/pulse/water-microbiology-hydraulics-plastics-biofilm-professor-tim-pnure
19 days ago
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Cleaning and disinfecting cleanrooms (video). Tim Sandle looks at cleaning and disinfecting cleanrooms, as a means of achieving contamination control:
www.youtube.com/watch?v=fqCP...
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Cleaning and disinfecting cleanrooms
YouTube video by Tim Sandle
https://www.youtube.com/watch?v=fqCPP3UHOv4
20 days ago
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Sterility, Sterilization and Sterility Assurance - introducing the second edition of Tim Sandle's new book
www.youtube.com/watch?v=yaru...
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Sterility, Sterilization and Sterility Assurance
YouTube video by Tim Sandle
https://www.youtube.com/watch?v=yaruEN8Ni1M
about 1 month ago
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Innovation with transparent antimicrobial coatings
www.pharmamicroresources.com/2025/08/inno...
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Innovation with transparent antimicrobial coatings
antimicrobial coatings
https://www.pharmamicroresources.com/2025/08/innovation-with-transparent.html
about 1 month ago
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Article: Considering the effects of different processes on bacterial spores, focusing on hydrogen peroxide. The killing mechanism is from oxidative damage to key proteins in the spore's inner membrane. But why are some spores resistant?
www.linkedin.com/pulse/bacter...
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Bacterial spore resistance: Spotlight on hydrogen peroxide
Many species of the orders Bacillales and Clostridiales form endospores. These remain dormant, and they are very resistant to decontamination and sterilization regimens.
https://www.linkedin.com/pulse/bacterial-spore-resistance-spotlight-hydrogen-professor-tim-pdwre/
about 1 month ago
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The Public Library Act 1850 enabled town councils to establish libraries and museums. One hundred and seventy-five years later, we’re still discovering the many benefits that public libraries offer their users.
about 1 month ago
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Rainfall intensity, soil saturation and snowmelt drive widespread landslide pathways, according to a new scientific study
www.digitaljournal.com/world/hydrol...
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Hydrological predictors: Identifying landslide threats
Rainfall intensity, soil saturation and snowmelt drive widespread landslide pathways, according to a new scientific study. Current methods to predict
https://www.digitaljournal.com/world/hydrological-predictors-identifying-landslide-threats/article
about 1 month ago
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Hoda Eldardiry, associate professor in the Department of Computer Science at Virginia Tech is working with a healthcare startup called LiteraSeed Inc. to launch a technology that bridges communication gaps between patients and their medical providers
www.digitaljournal.com/life/ai-expe...
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AI expert helps startup improve healthcare delivery
The best health services are well managed so as to achieve the core elements described above with a minimum wastage of resources.
https://www.digitaljournal.com/life/ai-expert-helps-startup-improve-healthcare-delivery/article
about 1 month ago
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A mysterious cosmic explosion has been traced to a massive stellar explosion. This cosmic event is showing fast X-ray transients (FXTs), which are blasts of X-rays from distant galaxies
www.digitaljournal.com/tech-science...
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Supernova’s jet is a source of fast X-ray transient
The new discovery represents the closest FXT associated with a supernova ever detected.
https://www.digitaljournal.com/tech-science/supernovas-jet-is-a-source-of-fast-x-ray-transient/article
about 1 month ago
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Will artificial intelligence be the salvation of humanity, a neutral force within which boundaries we will make our own destiny, or could AI destroy us?
www.digitaljournal.com/world/will-a...
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Will AI destroy humanity?
A detailed new forecast on AI progress, called AI 2027, predicts that Artificial General Intelligence (AGI) could send us on a new trajectory.
https://www.digitaljournal.com/world/will-ai-destroy-humanity/article
about 2 months ago
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Now available - antimicrobial action posters -
www.etsy.com/listing/1891...
about 2 months ago
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Scientists have developed a smart, bacteria-repelling coating based on resilin. When this substance is applied to surfaces like medical implants, scientists found that engineered resilin forms nano-droplets that physically disrupt bacterial cells
www.digitaljournal.com/tech-science...
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Science: Blocking bacterial infection with insect protein
These early results are very promising as a new way to help improve infection control in hospitals and other medical settings, but now more testing is needed to see how these coatings work against a wider range of harmful bacteria.
https://www.digitaljournal.com/tech-science/science-blocking-bacterial-infection-with-insect-protein/article
2 months ago
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Can we trust AI to deliver the best outcomes in pharmaceuticals and medicine? AI models can make basic errors when navigating ethical medical decisions. Researchers used ethical dilemmas and found AI often defaulted to intuitive but incorrect responses
www.digitaljournal.com/tech-science...
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AI's tendency to jump to conclusions poses risks in the medical context
Simple tweaks when using AI to review familiar medical cases expose blind spots that clinicians cannot afford to contend with. Is AI up for the task?
https://www.digitaljournal.com/tech-science/ais-tendency-to-jump-to-conclusions-poses-risks-in-the-medical-context/article
2 months ago
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A Humidex For The Cleanroom: Why Temperature And Humidity Control Matters
www.researchgate.net/publication/...
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(PDF) A Humidex For The Cleanroom: Why Temperature And Humidity Control Matters
PDF | Temperature and humidity control are important factors to control within the cleanroom. For pharmaceuticals and healthcare products, this relates... | Find, read and cite all the research you ne...
https://www.researchgate.net/publication/352853275_A_Humidex_For_The_Cleanroom_Why_Temperature_And_Humidity_Control_Matters
2 months ago
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A Humidex For The Cleanroom: Why Temperature And Humidity Control Matters
www.researchgate.net/publication/...
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(PDF) A Humidex For The Cleanroom: Why Temperature And Humidity Control Matters
PDF | Temperature and humidity control are important factors to control within the cleanroom. For pharmaceuticals and healthcare products, this relates... | Find, read and cite all the research you ne...
https://www.researchgate.net/publication/352853275_A_Humidex_For_The_Cleanroom_Why_Temperature_And_Humidity_Control_Matters
2 months ago
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Data integrity & microbiological data: Reviewing the essentials
www.linkedin.com/pulse/data-i...
#microbiology
#data
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Data integrity & microbiological data: Reviewing the essentials
Data integrity is applied to maintaining and assuring the accuracy and consistency of data over its entire life-cycle. In this sense, data integrity is the opposite to data loss and data corruption.
https://www.linkedin.com/pulse/data-integrity-microbiological-reviewing-essentials-professor-tim-zrnke/?trackingId=WxnyFu1hQRC3E4I%2FwriRDw%3D%3D
2 months ago
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Read my interview with Kairos Pharma's CEO Dr. John Yu- "We can block the signaling cascade that leads to the stem-like transformation of cancer cells. This stops resistance from progressing"
www.digitaljournal.com/tech-science...
@kairospharma
#cancer
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Q&A: Kairos Pharma and the fight against cancer drug resistance
Cancer drug resistance is one of the greatest obstacles in oncology. Even when therapy is initially effective, many tumors evolve over time.
https://www.digitaljournal.com/tech-science/qa-kairos-pharma-and-the-fight-against-cancer-drug-resistance/article
2 months ago
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What’s Inside a Bioprinter? Understanding the Machine That Prints Life
www.pharmamicroresources.com/2025/07/what...
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What’s Inside a Bioprinter? Understanding the Machine That Prints Life
Bioprinters in labs
https://www.pharmamicroresources.com/2025/07/whats-inside-bioprinter-understanding.html
2 months ago
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Airflow visualization - case studies - video from explaining the basics, supported by footage:
www.youtube.com/watch?v=cyhk...
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Airflow visualization - case studies
YouTube video by Tim Sandle
https://www.youtube.com/watch?v=cyhkpdG5GbM
3 months ago
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Airflow visualization - case studies
www.youtube.com/watch?v=cyhk...
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Airflow visualization - case studies
YouTube video by Tim Sandle
https://www.youtube.com/watch?v=cyhkpdG5GbM
3 months ago
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Coming soon from Tim Sandle - Sterility, Sterilisation and Sterility Assurance for Pharmaceuticals: Technology, Validation and Current Regulations (Woodhead Publishing Series in Biomedicine) 2nd Edition
www.amazon.com/Sterility-St...
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Sterility, Sterilisation and Sterility Assurance for Pharmaceuticals: Technology, Validation and Current Regulations (Woodhead Publishing Series in Biomedicine)
Sterility, Sterilisation and Sterility Assurance for Pharmaceuticals: Technology, Validation and Current Regulations (Woodhead Publishing Series in Biomedicine): 9780443364365: Medicine & Health Science Books @ Amazon.com
https://www.amazon.com/Sterility-Sterilisation-Assurance-Pharmaceuticals-Regulations/dp/0443364362?_encoding=UTF8&dib_tag=se&dib=eyJ2IjoiMSJ9.8_Ka9ernX4X2UqWSyduJyywJLRWxlyzpvHrO_5w3FA7GjHj071QN20LucGBJIEps.lvK4_sT4yKpGLJBQG8GSlSO8Ut1ViTBaO7zxICzh8VE&qid=1752611756&sr=8-1
3 months ago
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The Impact of Material Selection on Medical Equipment Performance
www.pharmamicroresources.com/2025/07/the-...
#medical
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The Impact of Material Selection on Medical Equipment Performance
Design of medical equipment
https://www.pharmamicroresources.com/2025/07/the-impact-of-material-selection-on.html
3 months ago
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Lichen from the Mojave Desert can survive, and replicate, under levels of extreme solar radiation – levels of radiation equivalent to that found on Earth-like planets in other solar systems
www.digitaljournal.com/tech-science...
3 months ago
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This week’s article asks, ‘do bacteria exhibit logical behavior?’ and answers ‘yes’. Examples include communication with each other, adapting to changing conditions, and demonstrating cooperative behaviors. See:
www.linkedin.com/pulse/making...
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Making sense of bacteria: Do microorganisms follow rules of logic?
Are microorganisms, like bacteria, logical in their exhibited behaviors? If so, in what way can scientists take advantage of these, even manipulate them through genetic engineering? This week’s articl...
https://www.linkedin.com/pulse/making-sense-bacteria-do-microorganisms-follow-rules-professor-tim-kvhle/
3 months ago
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Microbiology clothing, stationery, and ornaments. Here's a microbiology acrylic ornaments. featuring a beautiful, transparent construction and a string for easy placement. A dedicated store hosting a range of science and microbiology themed gifts, see:
www.etsy.com/.../microbio...
#microbiology
3 months ago
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Background history to the infected blood scandal in the book 'Blood, Plague, and Smallpox':
www.amazon.co.uk/Elstree-Labo...
#infectedbloodscandal
#news
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https://www.amazon.co.uk/Elstree-Laboratories-remarkable-scientific-excellence/dp/B0DRYNJ43V/
3 months ago
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New store for microbiology related gifts - BabblingBacteria:
www.etsy.com/uk/shop/Babb...
3 months ago
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Rare blue proteins from cold-adapted microbes can serve as prototypes to design molecular on-off switches for cells, according to a new study from the European Molecular Biology Laboratory
www.digitaljournal.com/tech-science...
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Switching on: Can Arctic microbes revolutionize neuroscience?
New microbial sensors? CryoRs are sensors for UV irradiation and are also capable of inward proton translocation modulated by UV light.
https://www.digitaljournal.com/tech-science/switching-on-can-arctic-microbes-revolutionize-neuroscience/article
3 months ago
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Does a change in smell lead our brains to switch interest from one thing to another? Scientists have been investigating how the brain makes decisions by participating in the storage of associations between different stimuli
www.digitaljournal.com/tech-science...
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Can a smell change your mind? Science links sensing scent to PSTD
Scientists have been investigating how the brain makes decisions by participating in the storage of associations between different stimuli.
https://www.digitaljournal.com/tech-science/can-a-smell-change-your-mind-science-links-sensing-scent-to-pstd/article
3 months ago
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reposted by
Tim Sandle
The Guardian
3 months ago
‘Like working in a volcano’: stories from six countries in Europe on a day of extreme heat
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‘Like working in a volcano’: stories from six countries in Europe on a day of extreme heat
How chefs, street performers and cheesemongers struggled to get their jobs done in record-busting temperatures
https://www.theguardian.com/world/2025/jul/05/stories-from-six-countries-europe-extreme-heat?utm_term=Autofeed&CMP=bsky_gu&utm_medium=&utm_source=Bluesky#Echobox=1751710554
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A new study by the University of Oxford shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in the following 18 months. The findings suggest a novel explanation for how vaccines produce this effect
www.digitaljournal.com/tech-science...
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How do vaccines reduce the risk of dementia?
A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is
https://www.digitaljournal.com/tech-science/how-do-vaccines-reduce-the-risk-of-dementia/article
3 months ago
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Bioprinters are basically the high-tech tools that turn the art of tissue engineering into reality. Imagine being able to print skin, muscle, or even little chunks of organs using cells instead of ink, that’s exactly what these magical machines do
www.pharmamicroresources.com/2025/06/how-...
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How Bioprinters Are Bringing Tissue Engineering to Life: Printing Cells Like Ink
Bioprinting & biology
https://www.pharmamicroresources.com/2025/06/how-bioprinters-are-bringing-tissue.html
3 months ago
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What Are Chemicals That Are Okay to Clean Your Home and Lab With?
www.pharmamicroresources.com/2025/06/what...
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What Are Chemicals That Are Okay to Clean Your Home and Lab With?
Cleaning chemicalsfor home and lab
https://www.pharmamicroresources.com/2025/06/what-are-chemicals-that-are-okay-to.html
4 months ago
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I’ll be speaking at the Sterility Testing Panel Discussion on June 26, 2025! Don’t miss out—register now to secure your spot!
event.on24.com/wcc/r/496814...
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Expert Perspectives: Balancing Time and Contamination Risks in Sterility Testing
Thursday, June 26, 2025 at 4:00 PM Central European Summer Time.
https://event.on24.com/wcc/r/4968144/F9E2270E6C07D8BE4069B9CCF97D22AA?partnerref=ExSpTim
4 months ago
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This week’s article takes a look at the human hair and the hair follicle microbiome, in part to further our understanding of contamination control. See:
www.linkedin.com/pulse/hair-r...
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Hair raising? Exploring the microbiome of human hair
There is a reasonable amount of literature on the human skin microbiome, including with reference to controlled environments (indeed this newsletter has looked into aspects of this fascinating area of...
https://www.linkedin.com/pulse/hair-raising-exploring-microbiome-human-sandle-ph-d-cbiol-fisct-nx5oe/
4 months ago
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How to Audit Your Cryopreservation Workflow for Microbial Risks
www.pharmamicroresources.com/2025/06/how-...
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How to Audit Your Cryopreservation Workflow for Microbial Risks
Cryopreservation for microbiology
https://www.pharmamicroresources.com/2025/06/how-to-audit-your-cryopreservation.html
4 months ago
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Please check out my microbiology videos on YouTube:
www.youtube.com/channel/UCJQ...
4 months ago
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There are several different approaches for evaluating disinfectant suitability - this article considers the Minimum Inhibitory Concentration (MIC). This is the lowest concentration of a disinfectant that prevents visible growth of a microorganism:
www.rssl.com/insights/lif...
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MIC & Disinfectant Efficacy: Understanding Antimicrobial Action
Dr Tim Sandle explores Minimum Inhibitory Concentration (MIC) and how it can be used to assess the suitability of disinfectants for contamination control
https://www.rssl.com/insights/life-science-pharmaceuticals/mic-disinfectant-efficacy-understanding-antimicrobial-action/
4 months ago
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Doctor Who cast change leads to surge in social media interest - Digital Journal
www.digitaljournal.com/entertainmen...
@doctorwhopn.bsky.social
#doctorwho
4 months ago
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Each May, to mark Ardbeg Day, the Ardbeg distillery releases a special expression of their range of peat-heavy and smoke-infused Scottish whiskies. The 2025 expression celebrates Islay’s iconic Fèis Ìle with the release of ‘Smokiverse’
www.digitaljournal.com/life/science...
4 months ago
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Free webinar- Designing a cleaning and disinfection field trial, 12th June 2025 at 2 p.m. UK time:
register.gotowebinar.com/register/742...
4 months ago
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