'In 1953, while working a hotel switchboard, a college graduate named Shea Zellweger began a journey of wonder and obsession that would eventually lead to the invention of a radically new notation for logic' @cabinetmagazine.bsky.social www.cabinetmagazine.org/issues/18/we...

Mapping the dynamics of phyllotaxis in Palms. Illustration from Carl Friedrich Philipp von Martius’s Historia naturalis palmarum, issued in 10 parts, 1823-50

One reason I developed LayNii IDA was to more easily explore my 0.35 mm multi echo human brain data. Here I’m observing blood motion artifacts across echos. The arterial signal *appear* to move across several millimeters. Best captured in short readout windows (e.g. ~3 ms readout windows in GRE).

The most primal generative experiences may be ones created by the visual cortex alone, or at least those involving the visual cortex in close collaboration with entheogenic triggers or light stimulation. Subjective Visual Phenomena – Johann Purkinje, 1819

I've always wanted to explore fMRI time series as a smooth, real-time movie. Now I can with LayNii IDA. Plus, with voxel-wise correlations on the fly. Fast, intuitive, and surprisingly insightful. 40 ms TR fMRI data from @practicalfmri.bsky.social ! @layerfmri.bsky.social @afni-pt.bsky.social

One more: Marshall Xu is presenting our latest updates in mapping brainstem vasculature at poster #1759, where he did some nifty image transformations + VesselBoost segmentation to get our best results yet. Take a look! @sbollmann.bsky.social @ofgulban.bsky.social ww6.aievolution.com/hbm2501/Abst...

Demonstrating anatomy-functional data registration of 11.7 T (!) partial-coverage human fMRI data at 0.7 × 0.7 × 0.8 mm resolution to help my colleague Alejandro Monreal-Madrigal. Who did a great work with this spiral readout acquisition. The data quality looks quite good 👏 youtu.be/Cgf8i-Lqrac

Devlog #1 for LayNii IDA, a GUI for meso-(f)MRI data Featuring whole human brain MRI datasets at: • 0.8 mm functional data • 0.35 mm in vivo multi-echo anatomical data • 0.075 mm ex vivo anatomical data Chronicling the development journey of neuroimaging software. youtu.be/ZFsBljNOcyw?...

Title text: "If you think curiosity without rigor is bad, you should see rigor without curiosity." Alt text: https://explainxkcd.com/3101#Transcript

In this blog post I am exploring the strange tension between rigor, reach, and recognition in modern science. What we gain (and lose) by just publishing the PDFs: thingsonthings.org/just-publish...

At today's layer-fMRI seminar, @ofgulban.bsky.social presented stunning high resolution vein mapping tools. It left me quite excited. youtu.be/0V8fSjo2T2w?...

New in LayNii v2.9.0: Introducing *LayNii IDA*, a high-performance tool for real-time interaction with ultra–high resolution MRI data. Built for speed, designed for discovery. Still early, but a big step toward the next era of 7T fMRI: higher resolution, larger datasets. github.com/layerfMRI/La...

In neuroimaging, we do skull stripping, but not brain stripping. Feels like favoritism.

[Field Note, Entry 05] - Refrain from repeating k-space experiment [Explosion_05]. What began as signal amplification now resembles an awakening. Frequencies folded in on themselves—revealing geometries that should not exist. - Proceeding further may breach more than spatial coherence...

The result of a large (42 authors!) collaboration: "Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation" arxiv.org/abs/2504.07824 TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.

I think ultra-high field MRI will be shifting toward ~0.35 mm voxels, even in routine use. This isn't just sharper images. We now directly see cortical layers, veins... It’s a leap, not a tweak. A few already crossed this threshold, but now it's becoming practical. More: doi.org/10.1101/2025...

We are recruiting for 5 permanent staff positions (Prof, Senior-, Lecturer) including for 7T-MRI. Please have a look and share widely. (Closing date: May 12) www.nature.com/naturecareer...

New layer-fMRI paper discussing an omnipresent artifact in layer-fMRI EPI data: Fuzzy Ripples. This artifact comes from short term gradient imperfections and represents the biggest limitation of layer-fMRI acquisition (wrt TRs, resolution, lower brain areas). doi.org/10.1002/mrm....

Mesoscopic veins appear as dark dots peppered across the middle gray matter surface—captured in living humans. High-precision cortex segmentation + T2*-weighted MRI at 0.35 mm isotropic resolution makes this possible. More at: doi.org/10.1101/2025...

In vivo reconstruction of Duvernoy's postmortem vasculature images - Fast, high-res imaging: Whole-brain 0.35 mm MRI in <7 min at 7 T - Vessel-type specific podt-processing: Capturing large leptomeningeal, pial, and intracortical meso-veins PDF: doi.org/10.1101/2025...

Dieter Appelt Partitur No. 39, 2018 At the Galerie Thomas Schulte www.galeriethomasschulte.com/artists/34-d...

New Layer-fMRI paper: T1234. A sequence that gets structural reference data, in 3-4 minutes. While also being optimized for applications in layer-fMRI studies. doi.org/10.1002/mrm.... Here a the MRM highlights video with practical tricks: youtu.be/9GBP9i1V3c4 By Kenny at al.

🚨 PhD opportunity alert! 🚨 Passionate about neuroscience? Want to work with cutting-edge tech like ultra-high field MRI and intracranial EEG to study the human brain? Join us and push the boundaries of neuroscience 🧠✨ 📍 @macsbio.bsky.social 📆 2 March 🔗 tinyurl.com/bfjwpmt9 #neurojobs #PhD

The layer-fMRI field has changed since the pandemic: -> studies are larger -> majority uses 3D readouts -> a bit more sharing -> majority uses non-BOLD contrasts

Never gets old

Dr. Seiji Ogawa discovered and coined "Blood Oxygenation Level Dependent" BOLD contrast - used in almost all fMRI today. It was my great honor to interview him over two days on the very beginnings of fMRI, and so much more. www.youtube.com/watch?v=6gBK...

This was a fun discussion! talking about the unique value of layer-fMRI and how I got there. Thanks Ben for having me at the BJKS Podcast.

I had a great discussion with Vesa Kiviniemi, from Oulu University. He described his latest work using high speed whole brain acquisition (MREG) to characterize brain pulsations - and perhaps hints of the glymphatic system. podcasts.apple.com/us/podcast/n...

Rather than a typical neurosalience Podcast, we decided to post a talk I gave at OHBM on my perspective on podcasting and Neurosalience - and how I prepare for each. creators.spotify.com/pod/show/ohb...

A new Neurosalience episode is out! The idea of the brain, Francis Crick, and consciousness with @fmri-today.bsky.social and Matthew Cobb (@matthewcobb.bsky.social) youtu.be/TE-vsX0wzjM

Behold the butterfly k-space trajectory: a maddening yet elegant dance across Fourier realms, conjuring cerebral truths from the void. Gaze upon the eldritch brain patterns it summons… if you dare.

Experiments in k-space. I call this one "explosion-02".

🚨 We’re hiring! 🚨 We're looking for a postdoc for our ERC Synergy project Unfold (unfold-lab.github.io). Join our lab at @institutpasteur to model brain morphogenesis! (1/10)

Just a heads-up: I officially invented 'Brain Sudoku' today. You're welcome. #MRI #brainart

I am always a bit suspicious of people giving advice on social media (how to write a paper, give an interview,…). If it works for them, fine. It may not work for you. My only advice is: don’t listen to advice. Including this one, of course.

Mark you calendar for the exciting upcoming ISMRM workshop on UHF & fMRI. March 31st-April 2nd 2025, in Annapolis, MD, USA. Website (being populated): www.ismrm.org/workshops/20... Preliminary program in figure.

Mistakes were made... Accidental brain art 🎨🧠 #brainart @layerfmri.bsky.social

I see you and raise you this bubble-sorted layers 🍰

Fascinating: mesoscopic vessels remain consistently visible across different T2*-weighted acquisitions! Here’s the same living human brain imaged 6 months apart using different parameters. Which image is your favorite?

While fine-tuning 3D EPI parameters, we captured an impressively clear view of the human LGN! If you look closely, you can almost make out faint layers—wish they were more distinct though 🫤

3D EPI has come so far! Here’s a whole-brain, 0.35 mm isotropic image we recently acquired, in under 7 minutes!!! So many potential applications (and analysis challenges) ahead... 🤯

In this video, I am showing how to quickly register anatomical images onto partial coverage fMRI data using ITKSNAP: youtu.be/2txoJiLsNbU

We have starting developing a *programming first* self-study pipeline to understand the fMRI signal in OHBM 2024 Brainhack. Might be useful for those who learn by interacting with the equations. A summary of the project can be found at: youtu.be/jQyK0ZV1LzY

Please mark your calendars for the 7th ‘layer-fMRI’ virtual dinner on Aug. 22nd. We will be discussing possible translational and clinical applications of layer fMRI. With: Esther Kuehn, Joost Haarsma, and Jun Hua More info: layerfmri.com/7thdinner/

10(!) 3yr post-doc/assistant prof jobs at the Pioneer Centre for SMARTbiomed, a Denmark-Oxford center led by Naomi Wray. Develop new stat/comp tools & software for key questions in common complex diseases. Jobs in Aarhus, Copenhagen or Oxford. smartbiomed.dk/join-the-cen...

Video of the live OHBM Neurosalience at #OHBM2024. Great discussion with Janaina Mourao-Miranda, Simon Eickhoff, Sepideh Sadaghiani, Thomas Yeo, and Michael Milham on Big Questions in Neuroimaging: Clinical Apps, Exciting developments, Brain mech insights www.youtube.com/watch?v=fsI8...

For an ERC-funded project Rainer Goebel is looking for enthusiastic academics interested in investigating mental imagery using laminar fMRI, AI and BCIs. For details see: www.academictransfer.com/en/342721/ph... www.academictransfer.com/en/342769/po...

Now that #OHBM2024 has passed, you can view all of the full abstracts in 6 large supplementary "papers" of Aperture Neuro! First of 6 is here. apertureneuro.org/article/1203...

This week, we share an In Memoriam Editorial by EiC @fmri-today.bsky.social et al. that pays tribute to Dr. Sean Marrett, a neuroscientist and active member of the international brain mapping community doi.org/10.52294/001...

Two year post doc position for 7T layer-fmri methods in infants at King's College London with Tom Arichi and Shaihan Malik. www.kcl.ac.uk/jobs/088006-...