Lizzie Maughan @uclchildhealth.bsky.social led this collaboration with Wenhui Song's lab to develop a bespoke airway stent for use in a 5-month-old with near-complete laryngeal stenosis. The novel 3D-printed stent enabled safe airway reconstruction. 📄 doi.org/10.1002/adfm...

Our latest work is available on BioRxiv! WS6 allows extended culture of basal epithelial cells and allows clonal expansion of primary airway epithelial cells after CRISPR editing, with clonal populations retaining their differentiation capacity. www.biorxiv.org/content/10.1...

Had a wonderful time at the @bsgct.bsky.social annual conference! I was delighted to be able to share our work on human airway epithelial cell culture for transplantation and how this contributes to the @epicentr.bsky.social efforts towards a cell and gene therapy for airway epidermolysis bullosa.

Yuki Ishii, @jess0rr.bsky.social Sam Janes, @robhynds.bsky.social @epicentr.bsky.social & team identify Wnt pathway activators as potential pro-regenerative therapies in their compound screen in human airway basal cells. journals.biologists.com/jcs/article/... journals.biologists.com/jcs/article/...

🚨Today our phenotypic screening work with primary human airway basal cells is published @jcellsci.bsky.social! We found that multiple Wnt activating compounds promote basal cell proliferation and validated 1-azakenpaullone in vivo. doi.org/10.1242/jcs....

Happy holidays from everyone in the EpiCENTR group! Follow @jess0rr.bsky.social and @drewfarr.bsky.social for our latest throughout 2025 🎁 (h/t scholargoggler.com)

Here's a starter pack that focusses on lung biology, regeneration and cancer. Let me know who I'm missing! go.bsky.app/VC83FZm