Me, post- surgery clerkship final exam, contemplating the prospect of dinner

Very important! Fat bear week is just around the corner Bear #4 has bear that just realized it isn't a walrus energy www.instagram.com/p/DOL5UspjiQ...

Votes are in: google cafes beat meta cafes on style+substance. Snack standings tbd

We’re international students at Harvard. We’re afraid to write this. But we have to speak up. www.washingtonpost.com/opinions/202...

The state of Georgia is using the body of a brain-dead woman as an incubator. Because she was 9 weeks pregnant when she died, and their abortion ban is from about 6 weeks, they are sustaining her on life support, without input from her family, until 32 weeks of gestation. A true dystopian nightmare.

Thank you for clarifying, good sir

PhD Timeline xkcd.com/3081

New look at resistance to allosteric inhibitors, and how (the right) drug combinations help overcome resistance. Sort of like distracting your cat with churu so you can clip their nails Review here: www.sciencedirect.com/science/arti...

Essential components for a thesis defense! 🥐 ☕️

The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New @nature.com www.nature.com/articles/d41... nature.com/articles/s41...

Vinod's team's work could have saved my wife's life, and I hope this and others like it will make a huge difference with patients with seemingly untreatable deadly diseases. This needs to be able to continue. www.mskcc.org/news/can-mrn...

This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH

NIH is abruptly terminating at least 33 research grants for projects studying why some people are hesitant to receive vaccines or evaluating strategies that could encourage vaccine uptake. scim.ag/4how23i

Wow. "NIH" canceled my co-mentored (with Dave Sulzer) PhD student's F31 funding. His work is on understanding the genetics and neuroscience of language learning disorders. F31 provides no indirect $ to Columbia, just pays his salary. Not that it should matter, but he's an American citizen. W.T.F.

Where should we implement changes in the professional+physical workplace environments of healthcare professionals to reduce burnout & improve workplace satisfaction? journals.lww.com/ajnonline/ab...

I'll be presenting my work prospectively studying clinical mutations and their impact on kinase inhibitor binding at #bps2025! Come see my talk on Wednesday morning @ 8:45am.

Thankful that indirect costs associated doomscrolling is broken up by all the cat pictures, here are my dues:

Will be spending the next 4 hours or saying things like “we have all year” or “how many cookies do you think you’ll eat this year” and “wait where did all the cookies go”

Starting off the week with scones and a recent preprint led by @sukritsingh92.bsky.social! Very cool comparative evaluation of mutation affinity prediction methods. Interesting differences in performance for das/imat, possibly due to conf-associated effects w/ the TII TKI

Here’s the updated Computational Biology Starter Pack! Let me know if you'd like to be included. go.bsky.app/QVPoZXp

Seaborn color palettes in the wild

Waiting for the first post to drop