JCC Featured Fellow Dr. Michelle Fry studies the structure of mitochondria – organelles that play important roles in cellular metabolism and signaling pathways. Fry uses the powerful technique cryoET to study mitochondrial shape right in their native environment in cells. @myfry.bsky.social 1/

Jane Coffin Childs Fellow Dr. Michelle Fry studies perhaps the most iconic organelle of the cell, the mitochondria. Almost everyone knows that mitochondria are the powerhouse of the cell, but few know they are essential for other functions like respiration and ... @myfry.bsky.social 1/

#AsgardArchaea team, led by @archaeal.bsky.social fr @texasscience.bsky.social — sequencing the DNA collected fr mouth of Rio de la Plata to the continental shelf of Uruguay to detect Asgards, a group of single-celled organisms & our closest microbial relatives on the tree of life. bit.ly/3MdniTH

Out in print! Using ancestral sequence reconstruction 🦖, in vivo characterization, and 🔬 analysis, we identified key residues in the mitochondrial protein #Mic60 that affect #respiration in #yeast. Since the preprint, we added some cool findings. 🧵⬇️ onlinelibrary.wiley.com/doi/10.1002/...

I’m thrilled to share that I will join @stowersinstitute.bsky.social this fall to explore the evolution and design of bioenergetic membranes in bacteria.

Meet Friederike Benning, PhD, the newest Jim and Virginia Stowers Fellow! Her research dives into the complexity of energy generation in evolution to reveal how bacteria build membranes to survive in extreme environments. 🦠 Learn more: bit.ly/3SCZQiM

Congrats Chen and colleagues (with shoutout to @myfry.bsky.social for connecting our labs)! JCI - SARM1 loss protects retinal ganglion cells in a mouse model of Autosomal Dominant Optic Atrophy www.jci.org/articles/vie...

It has been coming a long way... happy to share our latest work with you: www.biorxiv.org/content/10.1... Here, we show the importance of septal fortification by the Class A Penicillin Binding Protein, PBP1b, in E. coli and provide a molecular mechanism for this function. (1/12).

A new #preLight has appeared! ✨🔔 Barbora highlights a preprinted study from the Chao Lab (@lukechao.bsky.social) in which the structure-function relationship at the site of cellular respiration is under review. 👀 Check it out! ⬇️ prelights.biologists.com/highlights/a...

Great summary of our recent preprint by Barbora from @prelights.bsky.social. #mitochondria #cristae #respiration #asr

Excited to share our collaborative work characterizing a pathogenic mutation in Opa1 found in ADOA patients that began when Tom Schwarz @BostonChildrens presented a seminar @MGHMolBio biorxiv.org/content/10.1... @lukechao.bsky.social

Congrats to Siva Boopathy and team: www.sciencedirect.com/science/arti...

Happy to see our work out in @elife.bsky.social ! Lead by Tristan Bell and team. #EVs doi.org/10.7554/eLif...

How do baculoviruses protect their genome? Delighted to present our findings in print! We use cryo-EM to determine the structure of a baculoviral nucleocapsid. We show how the tiny capsid protein VP39 assembles into a giant nucleocapsid.❄️🔬 www.nature.com/articles/s41...

Excited to see Freddy's paper out in print! www.nature.com/articles/s41...

Great way to ring in the New Year from Siva Boopathy and colleagues: Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Mfn2 and Opa1 www.biorxiv.org/content/10.1...