Mitchell Grayson, MD
@mitchmd.bsky.social
📤 48
📥 57
📝 38
Physician-scientist studying the interaction of respiratory viral infections and allergic disease.
reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 23 hours ago
This study was a prospective, longitudinal cohort embedded within the Hong Kong Drug Allergy Delabelling Initiative. Adults referred for suspected penicillin allergy underwent standardized evaluation including skin test and drug provocation test. Learn more.
www.annallergy.org/article/S108...
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Prospective outcomes of penicillin allergy evaluation
Inaccurate penicillin allergy (PA) labels are associated with clinical and public health burdens. Although delabeling programs are effective, long-term data on the sustainability of delabeling and pat...
https://www.annallergy.org/article/S1081-1206(26)00065-7/fulltext
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reposted by
Mitchell Grayson, MD
Heather Cox Richardson (TDPR)
about 14 hours ago
I love the story of An Wang.
#WeAreHistory250
add a skeleton here at some point
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577
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reposted by
Mitchell Grayson, MD
Heather Cox Richardson (TDPR)
about 14 hours ago
Samuel Adams, as told by his biographer Stacy Schiff.
#WeAreHistory250
add a skeleton here at some point
10
490
130
reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
3 days ago
There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. This Yardstick provides evidence-based, expert opinion on how to diagnose and manage pediatric and adolescent hereditary angioedema.
www.annallergy.org/article/S108...
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Diagnosis and management of pediatric and adolescent hereditary angioedema
There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. Owing to this, patients now have several therapeutic options for mana...
https://www.annallergy.org/article/S1081-1206(26)00078-5/fulltext
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Forgot to tag this, so
#Medsky
#science
#NIH
#Immunology
#Immunosky
#Allergy
#Stupiddumbthingsthisadministrationalwaysdoes
#Whenwillthisend
#Imdonetaggingfornow
add a skeleton here at some point
7 days ago
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I just contributed to
@standupforscience.net
to help prevent the proposed new OMB policy for grants from going into effect. I encourage you to donate too!!!
secure.qgiv.com/for/svfpaps/...
If you don't know about the OMB policy, read this
www.npr.org/2026/06/03/n...
A disaster for US science!
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Stop Vought from Privatizing and Politicizing Science 1
https://secure.qgiv.com/for/svfpaps/?utm_source=ESMFR1&utm_medium=sms&utm_campaign=StopVought
7 days ago
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reposted by
Mitchell Grayson, MD
250 to 250
8 days ago
Mike Massimino is a former NASA astronaut, Columbia University Engineering Professor, and New York Times Bestselling Author. Massimino explains how the Hubble Space Telescope has revolutionized our understanding of outer space and serves as a testament to American ingenuity.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
8 days ago
Venom immunotherapy remains the only disease-modifying treatment for Hymenoptera (stinging insect) venom allergy. This study evaluates safety and efficacy of a novel 4-day outpatient VIT buildup protocol compared with established inpatient rush and ultrarush regimens.
bit.ly/4uCR7xW
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Novel 4-day outpatient Hymenoptera venom immunotherapy buildup protocol with low reaction rates
Hymenoptera stings can cause severe systemic reactions, including life-threatening anaphylaxis. Venom immunotherapy (VIT) remains the only disease-modifying treatment for Hymenoptera venom allergy. Co...
https://bit.ly/4uCR7xW
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reposted by
Mitchell Grayson, MD
250 to 250
9 days ago
Monica Land is a journalist, producer, and niece of civil rights icon Fannie Lou Hamer. Land remembers the inspiring life of the Mississippi voting rights activist who asked “Is this America?”
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
9 days ago
@govandybeshear.bsky.social
of Kentucky tells the story of Man o’ War, the prolific thoroughbred race horse who helped restore Americans’ faith in the country after World War I.
#WeAreAmerica250
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129
reposted by
Mitchell Grayson, MD
250 to 250
11 days ago
Michael Green is a Professor of History in UNLV's Department of History and teaches courses on nineteenth-century America and on Nevada and Las Vegas.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
10 days ago
Jan John is a retired sales executive, active volunteer in local Maine politics, Social Security beneficiary, and dog lover. Jan John reveals how pioneering Labor Secretary Frances Perkins fought to create Social Security benefits during the Great Depression.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
10 days ago
This review considers how biologic therapies have improved outcomes in severe asthma, and what research is needed to improve clinical remission rates. How can patient selection help target the underlying biological process in order to optimize the impact of biologic therapy?
bit.ly/48Uj5Nt
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Lessons learned regarding optimal use of biologics to achieve disease remission in severe asthma
Severe asthma management has changed dramatically in the last decade after the introduction of T2-directed biologic therapies. This has enabled more ambitious treatment goals, including on-treatment c...
https://bit.ly/48Uj5Nt
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma, & Immunology Editor-in-Chief
10 days ago
The June issue of Annals of Allergy, Asthma & Immunology explores
#remission
in
#food
#allergy
. The exciting "7 for 11 series" reviews
#foodallergy
and
#anaphylaxis
. Helping you provide the best care to your patients!
@annalsacaai.bsky.social
#Medsky
www.annallergy.org/current
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reposted by
Mitchell Grayson, MD
250 to 250
14 days ago
Dr. Jelani Cobb is an author, journalist, and Dean of Columbia Journalism School. Cobb tells the story of John Peter Zenger, a newspaperman whose trial for printing critical statements about the royal governor of New York helped to define freedom of the press.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
14 days ago
Former Montana Senator Jon Tester is a third-generation farmer and former school teacher who has served at the local, state, and federal levels of government. Tester explores the origins and influence of Yellowstone, America’s first national park.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
15 days ago
Cleve Jones is a human rights advocate, author, and lecturer who joined the gay liberation movement in 1972, co-founded the San Francisco AIDS Foundation in 1983, and founded the AIDS Memorial Quilt—one of the world’s largest community arts projects—in 1987.
#WeAreAmerica250
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126
reposted by
Mitchell Grayson, MD
250 to 250
15 days ago
Maura Healey is the 73rd Governor of Massachusetts, the state’s first woman and first openly LGBTQ person elected to the position. Governor Healy recounts the Battles of Lexington and Concord, the opening salvos of the Revolutionary War.
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reposted by
Mitchell Grayson, MD
250 to 250
16 days ago
Sylvia Salazar is a Colombian-born engineer turned political content creator and activist. She is the founder of Tono Latino. Here, Salazar details the life of pioneering Latino journalist Rubén Salazar, who sought the growth of the Chicano movement in the 1960s.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
17 days ago
Senator Chris Murphy of Connecticut tells us about Charter Oak, a lasting symbol of independence and American ingenuity at keeping it.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
15 days ago
Annals of Allergy, Asthma & Immunology’s commitment to aiding clinical allergists in their care of patients is well reflected in this month’s edition, which is dedicated to the treatment of asthma. Find out what's new in the care of patients with asthma.
bit.ly/42xyMXf
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What’s new in the care of patients with asthma?
Annals of Allergy, Asthma & Immunology’s commitment to aiding clinical allergists in their care of patients is well reflected in this month’s edition, which is dedicated to the treatment of asthma.
https://bit.ly/42xyMXf
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
17 days ago
Is there cross-reactivity between amoxycillin and piperacillin-tazobactam? If so, how can an allergist best protect those at risk? Learn how this study aims to establish a link between the two and what the results show for safer patient care.
bit.ly/490rvD3
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Cross-reactivity between amoxicillin and piperacillin–tazobactam in patients with amoxicillin allergy: A prospective study
Amoxicillin (AX) is the most frequently prescribed β-lactam antibiotic in the USA and Europe and a leading cause of drug-induced hypersensitivity. Although cross-reactivity between aminopenicillins an...
https://bit.ly/490rvD3
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
22 days ago
Longitudinal changes in percentage of forced expiratory volume in 1 second allows clustering of patients with severe asthma into 3 groups with disparate clinical and inflammatory profiles, which may drive treatment choice.
bit.ly/4u8oyZs
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Clustering of patients with severe asthma based on long-term percentage of forced expiratory volume in 1 second (FEV1) changes
Severe asthma is a heterogeneous disease with variable clinical manifestations and treatment responses. Long-term assessment of lung function trajectories may help define phenotypic and endotypic subg...
https://bit.ly/4u8oyZs
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reposted by
Mitchell Grayson, MD
250 to 250
16 days ago
United States Representative Jamie Raskin is the ranking member of the House Committee on the Judiciary. Here, Representative Raskin shares how Thomas Paine’s Common Sense defined the stakes of the American revolution.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
17 days ago
Ariana DeBose is a dancer, singer, and Academy Award-winning actress. DeBose tells us about the inspiring and pioneering life of Puerto Rican singer, actress, dancer, and activist Rita Moreno.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
18 days ago
Heather Cox Richardson tells the story of the Constitutional Convention, where 55 delegates constructed the framework for a new government.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
250 to 250
18 days ago
Introducing 250 to 250: A series of one-minute stories of the many people, places, and events that have built our country and remind us of the power of each person to make history.
#WeAreAmerica250
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
23 days ago
The American College of Allergy, Asthma & Immunology (ACAAI) is supporting a trial initiative by Annals of Allergy, Asthma & Immunology to support Open Access of NIH-funded research. Learn more.
www.annallergy.org/article/S108...
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Open access is essential for research funded by the National Institutes of Health (NIH)
In July of 2025, the National Institutes of Health (NIH) instituted a new policy (the “2024 NIH Public Access Policy”) which requires that all publications from NIH-funded research be made publicly av...
https://www.annallergy.org/article/S1081-1206(26)00024-4/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
24 days ago
50-91% of asthma patients of all disease severities have small airways dysfunction. This study compares the aerodynamic particle size distribution of 3 triple combination inhalers to discern which best targets the small airways.
bit.ly/42xDWm4
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Relative particle size and distribution of inhaled triple therapies
Many patients with asthma or chronic obstructive pulmonary disease have small airways dysfunction, the presence of which has clinical implications including poor disease control and worse health statu...
https://bit.ly/42xDWm4
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
28 days ago
Improving asthma control in pregnancy requires consistent, evidence-based messaging, multidisciplinary care, and shared decision-making. This CME review focuses on strategies to optimize asthma control throughout pregnancy. Learn more:
bit.ly/4376H9m
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Asthma in pregnancy: Optimizing treatment strategies and the emerging role of biologic therapies
Asthma is the most common chronic respiratory disease during pregnancy and is a major contributor to preventable maternal morbidity and adverse fetal outcomes when poorly controlled. Although most ast...
https://bit.ly/4376H9m
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
30 days ago
Does the lack of detectable IgE predict noninfectious complications of common variable immunodeficiency (CVID)? Find out in this study of 149 patients with CVID.
bit.ly/433jIAP
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Undetectable IgE association with noninfectious complications of common variable immune deficiency
Undetectable IgE levels are a frequent feature of common variable immunodeficiency (CVID). However, not much is known regarding the role of IgE levels as a prognostic factor in patients with CVID.
https://bit.ly/433jIAP
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I thought I'd share this nice write-up about me with all of you. Enjoy! 😀
www.emjreviews.com/allergy-immu...
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Viruses and Immunity: Interview with Mitchell H. Grayson
My father trained as a dermatologist and then became board certified in allergy and immunology the first year that allergy and immunology...
https://www.emjreviews.com/allergy-immunology/article/viruses-and-immunity-interview-with-mitchell-h-grayson/
about 1 month ago
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma, & Immunology Editor-in-Chief
about 1 month ago
The May issue of Annals of
#Allergy
, Asthma &
#Immunology
has bloomed! This month is all about
#asthma
-- read up to find out the latest information so you can provide the best care to your patients!
#medsky
@annalsacaai.bsky.social
www.annallergy.org/current
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 1 month ago
This Distinguished Author review outlines the early history of common variable immunodeficiency (CVID), diagnostic criteria and workup of subjects, clinical manifestations, emerging genetic understandings, and current treatment for patients with this immune defect.
www.annallergy.org/article/S108...
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Current concepts: Common variable immunodeficiency
Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency disorder found in clinical medicine. The immune defect occurs in males and females equally and is char...
https://www.annallergy.org/article/S1081-1206(25)01349-3/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 1 month ago
Dupilumab significantly and rapidly improved asthma symptoms, pulmonary function, and FeNO values in patients with asthma comorbid with refractory eosinophilic chronic rhinosinusitis, and these improvements were sustained over time. Find out more:
www.annallergy.org/article/S108...
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Clinical remission of comorbid asthma during dupilumab treatment in patients with high-burden eosinophilic chronic rhinosinusitis
Eosinophilic chronic rhinosinusitis (ECRS), a refractory subtype of chronic rhinosinusitis, frequently coexists with asthma. CRS can exacerbate the asthma burden, contributing to poor disease control....
https://www.annallergy.org/article/S1081-1206(25)01357-2/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 1 month ago
Authored by members of the Clinical Immunology and Autoimmune Disease Committee, these 10 bullets center on clinical pearls and signs that inborn errors of immunity (previously known as primary immunodeficiency diseases) might be present in your patients.
www.annallergy.org/article/S108...
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10 Ways to improve your recognition of inborn errors of immunity
Annals has initiated a project that periodically publishes guidance to help bridge knowledge gaps and unmet needs that arise among publication of society guidelines, yardsticks and working group repor...
https://www.annallergy.org/article/S1081-1206(25)01387-0/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 1 month ago
The pharmacokinetics and pharmacodynamics of single dose and repeat doses of sublingual (AQST-109) and intramuscular epinephrine were compared in healthy adults. Learn how they compared:
www.annallergy.org/article/S108...
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Pharmacokinetics and pharmacodynamics of AQST-109
Intramuscular epinephrine administered via manual injection, autoinjector, or as a nasal spray are the current first-line treatments for anaphylaxis. AQST-109 is a needle- and device-free sublingual a...
https://www.annallergy.org/article/S1081-1206(25)01363-8/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 2 months ago
More than 75 years later, the Nuremberg Code remains a relevant framework for performing ethical research and has important implications for research and clinical practice in allergy and immunology. Learn about its foundation and why it is still important:
www.annallergy.org/article/S108...
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The Nuremberg Code and its lasting relevance to allergy and immunology
During World War II, Nazi physicians conducted nonconsensual experiments on concentration camp prisoners which often resulted in death or permanent disabilities. They tested the limits of the human bo...
https://www.annallergy.org/article/S1081-1206(25)01385-7/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 2 months ago
This document, authored by ACAAI's Clinical Immunology and Autoimmune Disease Committee, provides a clinically focused update on optimizing artificial intelligence (AI) to diagnose and treat inborn errors of immunity. Read the recommendations:
www.annallergy.org/article/S108...
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10 Ways to improve your use of artificial intelligence in inborn errors of immunity
Annals of Allergy, Asthma & Immunology has launched a section, “10 Ways You Can Improve X,” aimed at bridging knowledge gaps and addressing unmet needs that arise among the publication of society guid...
https://www.annallergy.org/article/S1081-1206(25)01388-2/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 2 months ago
This study evaluated the clinical efficacy and safety of patients in different age groups who were started on Cow's Milk oral immunotherapy based on real-life data on reaction profiles and treatment processes. See what they learned:
www.annallergy.org/article/S108...
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Timing of cow’s milk oral immunotherapy and adverse reactions in children: A 15-year experience
Cow’s milk allergy (CMA) is one of the most common food allergies in children and may persist into later childhood. Oral immunotherapy (OIT) is an effective treatment option; however, the optimal timi...
https://www.annallergy.org/article/S1081-1206(26)00035-9/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
about 2 months ago
Since the last practice parameter for inborn errors of immunity (IEI) in 2015, there have been significant advances in genetic testing and identification of novel pathogenic gene variants causing IEI. See the latest practice parameter here:
www.annallergy.org/article/S108...
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2025 Inborn errors of immunity practice parameter
The Joint Task Force on Practice Parameters (JTFPP) was commissioned by the American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI) ...
https://www.annallergy.org/article/S1081-1206(25)01300-6/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
2 months ago
Although 1 in 10 people have a penicillin allergy label on their electronic health record, more than 90% do not truly have penicillin allergy. This study looks at racial differences in penicillin allergy mislabels, a process termed “delabeling.”
www.annallergy.org/article/S108...
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Racial differences in penicillin allergy delabeling in a multicenter US primary care cohort
Penicillin allergy labels affect 1 in 10 people but are uncommonly reflective of a true, IgE–mediated allergy. Penicillin allergy–labeled patients have increased exposure to broad-spectrum antibiotics...
https://www.annallergy.org/article/S1081-1206(25)01366-3/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
2 months ago
This study demonstrates differences in self-reported food allergens by race/ethnicity and anaphylaxis symptom recognition, epinephrine access, and food allergy-related health care utilization by race/ethnicity and insurance status. Find out what they learned:
www.annallergy.org/article/S108...
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Identifying gaps
Food allergy (FA) disproportionately affects communities of color in the United States. However, few studies have evaluated adult-specific disparities in FA.
https://www.annallergy.org/article/S1081-1206(25)01308-0/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
2 months ago
Who actually has asthma? Researchers explored incorporating spirometry with bronchodilator response to determine asthma incidence, severity, control, and diagnostic performance across 4 definitions in patients hospitalized for bronchiolitis in the 1st year of life.
www.annallergy.org/article/S108...
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Who actually has asthma? The challenge of defining and diagnosing asthma
Asthma diagnosis is based on identifying a pattern of nonspecific and variable symptoms including recurrent episodes of cough, shortness of breath, chest tightness, and wheezing that can mimic a wide ...
https://www.annallergy.org/article/S1081-1206(25)01354-7/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma, & Immunology Editor-in-Chief
2 months ago
The March issue of Annals of
#Allergy
,
#Asthma
&
#Immunology
is everything
#Immunodeficiency
. A new
#PracticeParameter
to an outstanding review of
#CVID
- this issue is packed with info so you can provide up-to-date care for your patients!
@annalsacaai.bsky.social
#MedSky
www.annallergy.org/current
0
3
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
2 months ago
The shared decision-making process may have an important function for providers: helping to assess whether a family's anxiety level and investment in the process makes their child a good fit for oral immunotherapy treatment for food allergies.
www.annallergy.org/article/S108...
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Goldilocks zone: Allergists’ perceptions of family anxiety and investment in food allergy oral immunotherapy
Oral immunotherapy (OIT) is an increasingly popular but still contentious treatment option for food allergies. Because most patients receiving OIT are children, families’ involvement in treatment is a...
https://www.annallergy.org/article/S1081-1206(25)01289-X/fulltext
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
2 months ago
Among children with food allergies (FA), 77% report a history of atopic dermatitis (AD), with more than 80% of children with FA developing AD within the first year of life. So which factors are involved with early onset or late onset AD? Find out:
www.annallergy.org/article/S108...
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The age of eczema onset and multiple food allergies
Atopic dermatitis (AD) is the most common pediatric atopic disease and a risk factor for food allergy (FA) development. Children with AD are prone to developing allergic comorbidities. Its relationshi...
https://www.annallergy.org/article/S1081-1206(25)01369-9/abstract
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Simple request for
#NoKings
day!!
3 months ago
0
0
0
reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
3 months ago
A study of consultative practices, management of allergist-immunologists engaging in inborn errors of immunity care demonstrates a critical need for enhanced training, access to multidisciplinary support, and targeted CE to optimize care for patients.
www.annallergy.org/article/S108...
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Lessons from the American College of Allergy, Asthma and Immunology inborn errors of immunity survey
Inborn errors of immunity (IEIs) have been increasingly well characterized on the molecular and genetic levels. Their clinical recognition and management among practicing allergist-immunologists remai...
https://www.annallergy.org/article/S1081-1206(25)01224-4/fulltext
0
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reposted by
Mitchell Grayson, MD
Annals of Allergy, Asthma & Immunology
3 months ago
When effectiveness is equal, some hereditary angioedema patients prefer injectable medication, others an oral administration for long term prophylactic (LTP) treatment. By better understanding patients’ preferences, LTP recommendations can be individualized.
www.annallergy.org/article/S108...
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Long-term prophylactic treatment preferences and willingness to switch therapy in individuals with hereditary angioedema
Long-term prophylaxis (LTP) can help manage hereditary angioedema (HAE). With increasing LTP treatment options, understanding patients’ preferences is important for shared decision-making.
https://www.annallergy.org/article/S1081-1206(25)01383-3/fulltext
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