This study was a prospective, longitudinal cohort embedded within the Hong Kong Drug Allergy Delabelling Initiative. Adults referred for suspected penicillin allergy underwent standardized evaluation including skin test and drug provocation test. Learn more. www.annallergy.org/article/S108...

There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. This Yardstick provides evidence-based, expert opinion on how to diagnose and manage pediatric and adolescent hereditary angioedema. www.annallergy.org/article/S108...

Venom immunotherapy remains the only disease-modifying treatment for Hymenoptera (stinging insect) venom allergy. This study evaluates safety and efficacy of a novel 4-day outpatient VIT buildup protocol compared with established inpatient rush and ultrarush regimens. bit.ly/4uCR7xW

The June issue of Annals of Allergy, Asthma & Immunology explores #remission in #food #allergy. The exciting "7 for 11 series" reviews #foodallergy and #anaphylaxis. Helping you provide the best care to your patients! @annalsacaai.bsky.social #Medsky www.annallergy.org/current

This review considers how biologic therapies have improved outcomes in severe asthma, and what research is needed to improve clinical remission rates. How can patient selection help target the underlying biological process in order to optimize the impact of biologic therapy? bit.ly/48Uj5Nt

Annals of Allergy, Asthma & Immunology’s commitment to aiding clinical allergists in their care of patients is well reflected in this month’s edition, which is dedicated to the treatment of asthma. Find out what's new in the care of patients with asthma. bit.ly/42xyMXf

Is there cross-reactivity between amoxycillin and piperacillin-tazobactam? If so, how can an allergist best protect those at risk? Learn how this study aims to establish a link between the two and what the results show for safer patient care. bit.ly/490rvD3

Longitudinal changes in percentage of forced expiratory volume in 1 second allows clustering of patients with severe asthma into 3 groups with disparate clinical and inflammatory profiles, which may drive treatment choice. bit.ly/4u8oyZs

The American College of Allergy, Asthma & Immunology (ACAAI) is supporting a trial initiative by Annals of Allergy, Asthma & Immunology to support Open Access of NIH-funded research. Learn more. www.annallergy.org/article/S108...

50-91% of asthma patients of all disease severities have small airways dysfunction. This study compares the aerodynamic particle size distribution of 3 triple combination inhalers to discern which best targets the small airways. bit.ly/42xDWm4

Improving asthma control in pregnancy requires consistent, evidence-based messaging, multidisciplinary care, and shared decision-making. This CME review focuses on strategies to optimize asthma control throughout pregnancy. Learn more: bit.ly/4376H9m

The May issue of Annals of #Allergy, Asthma & #Immunology has bloomed! This month is all about #asthma -- read up to find out the latest information so you can provide the best care to your patients! #medsky @annalsacaai.bsky.social www.annallergy.org/current

Does the lack of detectable IgE predict noninfectious complications of common variable immunodeficiency (CVID)? Find out in this study of 149 patients with CVID. bit.ly/433jIAP

This Distinguished Author review outlines the early history of common variable immunodeficiency (CVID), diagnostic criteria and workup of subjects, clinical manifestations, emerging genetic understandings, and current treatment for patients with this immune defect. www.annallergy.org/article/S108...

Dupilumab significantly and rapidly improved asthma symptoms, pulmonary function, and FeNO values in patients with asthma comorbid with refractory eosinophilic chronic rhinosinusitis, and these improvements were sustained over time. Find out more: www.annallergy.org/article/S108...

The pharmacokinetics and pharmacodynamics of single dose and repeat doses of sublingual (AQST-109) and intramuscular epinephrine were compared in healthy adults. Learn how they compared: www.annallergy.org/article/S108...

Authored by members of the Clinical Immunology and Autoimmune Disease Committee, these 10 bullets center on clinical pearls and signs that inborn errors of immunity (previously known as primary immunodeficiency diseases) might be present in your patients. www.annallergy.org/article/S108...

More than 75 years later, the Nuremberg Code remains a relevant framework for performing ethical research and has important implications for research and clinical practice in allergy and immunology. Learn about its foundation and why it is still important: www.annallergy.org/article/S108...

This document, authored by ACAAI's Clinical Immunology and Autoimmune Disease Committee, provides a clinically focused update on optimizing artificial intelligence (AI) to diagnose and treat inborn errors of immunity. Read the recommendations: www.annallergy.org/article/S108...

This study evaluated the clinical efficacy and safety of patients in different age groups who were started on Cow's Milk oral immunotherapy based on real-life data on reaction profiles and treatment processes. See what they learned: www.annallergy.org/article/S108...

Since the last practice parameter for inborn errors of immunity (IEI) in 2015, there have been significant advances in genetic testing and identification of novel pathogenic gene variants causing IEI. See the latest practice parameter here: www.annallergy.org/article/S108...

Although 1 in 10 people have a penicillin allergy label on their electronic health record, more than 90% do not truly have penicillin allergy. This study looks at racial differences in penicillin allergy mislabels, a process termed “delabeling.” www.annallergy.org/article/S108...

This study demonstrates differences in self-reported food allergens by race/ethnicity and anaphylaxis symptom recognition, epinephrine access, and food allergy-related health care utilization by race/ethnicity and insurance status. Find out what they learned: www.annallergy.org/article/S108...

Who actually has asthma? Researchers explored incorporating spirometry with bronchodilator response to determine asthma incidence, severity, control, and diagnostic performance across 4 definitions in patients hospitalized for bronchiolitis in the 1st year of life. www.annallergy.org/article/S108...

The shared decision-making process may have an important function for providers: helping to assess whether a family's anxiety level and investment in the process makes their child a good fit for oral immunotherapy treatment for food allergies. www.annallergy.org/article/S108...

Among children with food allergies (FA), 77% report a history of atopic dermatitis (AD), with more than 80% of children with FA developing AD within the first year of life. So which factors are involved with early onset or late onset AD? Find out: www.annallergy.org/article/S108...

A study of consultative practices, management of allergist-immunologists engaging in inborn errors of immunity care demonstrates a critical need for enhanced training, access to multidisciplinary support, and targeted CE to optimize care for patients. www.annallergy.org/article/S108...

When effectiveness is equal, some hereditary angioedema patients prefer injectable medication, others an oral administration for long term prophylactic (LTP) treatment. By better understanding patients’ preferences, LTP recommendations can be individualized. www.annallergy.org/article/S108...

This study aims to assess sex-based differences in perioperative hypersensitivity and explore potential differences by age, culprit drugs and reaction severity. www.annallergy.org/article/S108...

A large pediatric Asian American FPIES cohort demonstrates distinguishing features, including a high proportion of egg FPIES and lack of common food co-associations. Understanding these differences may enhance clinicians’ ability to diagnose, manage FPIES. www.annallergy.org/article/S108...

Iodinated contrast media is used in radiology to enhance visibility of organs and blood vessels for patients undergoing CT imaging. A study evaluates the frequency of anaphylactic reactions to ICM during contrast-enhanced CT imaging. Learn more. www.annallergy.org/article/S108...

This study reveals that hyperglycemia was associated with small airway dysfunction and preserved ratio impaired spirometry in asthma. Soluble receptor for advanced glycation end products may be a biomarker of hyperglycemia-associated lung dysfunction. www.annallergy.org/article/S108...

Basophils are gaining recognition as clinically actionable contributors to atopic dermatitis. The basophil activation test offers promise for assessing AD pathogenesis and response to treatment. www.annallergy.org/article/S108...

A study assesses how lung function trajectories have been modelled across the literature, combining systematic search with bibliometric analysis of 1919 longitudinal studies. To advance lung function research, a more comprehensive approach is required. www.annallergy.org/article/S108...

Read a focused overview of inflammatory conditions in which pruritus is the major burden, learn about fundamental immune pathways, and sensory circuits involved, as well as efficacies and safety profiles of novel therapies addressing chronic pruritus. www.annallergy.org/article/S108...

The March issue of Annals of #Allergy, #Asthma & #Immunology is now available. Learn about current and future treatments for #urticaria. As always the most up-to-date information allows you to take best care of your patients. See more at: www.annallergy.org/current @annalsacaai.bsky.social #Medsky

The American College of Allergy, Asthma & Immunology (ACAAI) is supporting a new trial initiative by Annals of Allergy, Asthma & Immunology to support Open Access of NIH-funded research. Learn more. www.annallergy.org/article/S108...

Learn what the most cited articles from Annals are! Access them in the Most Cited area about halfway down the Annals homepage: www.annallergy.org

This article investigates the predictive effect of eosinophil-to-lymphocyte ratio from peripheral blood tests, combined with ethmoid sinus-to-maxillary sinus ratio, and ethmoid sinus score minus maxillary sinus score on olfactory recovery in patients with CRSwNP. www.annallergy.org/article/S108...

Do you want to write an article for Annals? Here are our guidelines: www.annallergy.org/content/auth...

Does tezepelumab reduce asthma exacerbations attributed to respiratory infections in patients with severe, uncontrolled asthma compared with placebo? Irrespective of perennial allergy status? Find out: www.annallergy.org/article/S108...

Wonder what your colleagues are reading in Annals? Take a look at the Most Read (Last 30 Days) section of the Annals homepage and find out! www.annallergy.org

The most common inflammatory airway diseases are asthma, chronic obstructive pulmonary disease, bronchiectasis, and obstructive sleep apnea. Overlap syndromes involving asthma are especially frequent and often exhibit bidirectional relationships. Learn more. www.annallergy.org/article/S108...

Did you read the article we posted on Tuesday? Have thoughts to share? We welcome correspondence. Share yours here: [email protected]

With at least 14 states restricting cell phone use in schools, allergist-immunologists may increasingly be asked to write letters of medical necessity for a child to carry a cell phone at school. https://loom.ly/IDMPGaI

It is here - the February issue of Annals of Allergy, Asthma & Immunology! This month we focus on #atopic #dermatitis. Find the information needed to provide the best care to your #allergy patients. #MedSky #Immunology @annalsacaai.bsky.social www.annallergy.org/current

Earn CME credit with Annals' CME online exams! Read an article in Annals, then take an exam for CME credit! Learn more: www.annallergy.org/cme/home

What do you do when you want to run a clinical question by a colleague, have another allergist look at a patient’s rash, or have a billing question? Find out why allergists need to see other allergists. www.annallergy.org/article/S108...

Nutritional management is a cornerstone of care for infants with food protein-induced enterocolitis syndrome (FPIES). Learn more about the involvement of an allergist and a dietitian to ensure adequate growth, timely food introduction, caregiver confidence and more. https://loom.ly/RjAJ_qI

This study analyzed the impact of 4 biologics (benralizumab, dupilumab, mepolizumab, and omalizumab) on prebronchodilator lung function parameters using spirometry and the gas dilution method after 6 and 12 months of treatment in adults with severe asthma. https://loom.ly/zGFwTK8