We are grateful for our readers and authors, reviewers and editors. We are grateful for more than 80 years of publication, as we document our experience, discoveries, our growth in allergy, asthma and immunology. Happy Thanksgiving from Annals!

The December issue of Annals of Allergy, Asthma & Immunology is here -- dedicated to Food Protein Induced Enterocolitis Syndrome (FPIES). Read and learn more at www.annallergy.org/current And oh, what a great holiday cover image (see below)! @annalsacaai.bsky.social #MedSky #allergy #immunology

A woman with indolent #SystemicMastocytosis presented with #Anaphylaxis following consumption of ackee fruit. Case report in @annalsacaai.bsky.social#SystemicMastocytosis#Anaphylaxis Read here: https://bit.ly/4oguPOW #RareDisease #MedSky #Immunology

Multiple factors can contribute to the increase in infections in AD. Skin barrier defects, immune dysregulation, and skin flora dysbiosis all contribute to the increased risk of infections in AD. Learn more and earn CME! https://loom.ly/D4Y1-rs

There is a lack of diversity and representation of historically marginalized groups in current clinical research. The primary objective for this study was to evaluate recruitment and retention strategies for patients historically marginalized in asthma clinical trials. https://loom.ly/sVcJ-vM

One of the first-line options for long term prophylaxis in HAE patients is lanadelumab, a fully human monoclonal antibody inhibiting plasma kallikrein. The authors report findings from 2 prospective, noninterventional, multicenter phase 4 studies. Learn more: https://loom.ly/gMx757w

Ready to submit an article? Share your expertise and submit it here: https://loom.ly/uBd7yU4

This review discusses drug hypersensitivity reactions in mastocytosis, focusing on the most frequent drug triggers and their management. A history-driven, evidence-based approach allows most patients to be treated effectively without unnecessary drug avoidance. https://loom.ly/nlkd5RY

Chronic rhinosinusitis (CRS) is a common condition evaluated by the allergist-immunologist. Here are 10 things you should know about this common and important condition. https://loom.ly/JT_dPHQ

Several new agents have received Food and Drug Administration approval, expanding therapeutic options for patients. These innovations represent a shift toward personalized atopic dermatitis management. Learn more: https://loom.ly/hszCE8g

Do you want to write an article for Annals? Here are our guidelines: www.annallergy.org/content/auth...

Earn CME credit with Annals' CME online exams! Read an article in Annals, then take an exam for CME credit! Learn more: https://loom.ly/h7upvqk

Did you know Annals features collections of articles based on topic? Asthma, Clinical Practice, Drug Allergy, Immunodeficiency, Rhinosinusitis, and more! Access them in the Collections area about halfway down the Annals homepage: https://loom.ly/qDK5bcY

How do you systematically synthesize the benefits and harms of triple therapy (ICS/LABA/long-acting muscarinic antagonists) compared with dual therapy (ICS/LABA) for asthma management across key subpopulations? Find out here: https://loom.ly/C3UpA6E

Two respiratory viruses associated with most recurrent wheeze and asthma development are respiratory syncytial virus (RSV) and rhinovirus (RV). This review evaluates the roles these 2 viruses play in the development of wheeze and asthma. https://loom.ly/hDm2aaI

Come to this years American College of Allergy, Asthma & Immunology meeting - it is going to be great! I'll be there presenting the best from Annals from the last year. Hope to see you in Orlando! (register at annualmeeting.acaai.org/2025 ) @annalsacaai.bsky.social #ACAAI25

Who's this year's winner of the "Pathy" award? (wink, wink) Who was nominated? Who won? Find out in Marginal Zone, only in Annals of Allergy, Asthma & Immunology. https://loom.ly/vx0R1C8

Asthma disproportionately affects non–English-speaking populations, with language barriers contributing to worse health outcomes, including increased emergency department visits and hospitalizations. Find out what health systems can do to reduce disparities. https://loom.ly/oUepsUM

Student health center or clinic administration of subcutaneous immunotherapy (SCIT) while at college/university is not well studied. This study aimed to clarify SCIT administration on campus both from the Allergist’s and student health center's perspectives. https://loom.ly/7DZZCHM

This study hoped to better understand the experiences of college students with and without food allergy (FA) to determine ways to improve safety and quality of life for those with FA. Were they successful? Find out: https://loom.ly/LRKese4

Childhood asthma is more common in boys; however, its prevalence decreases more significantly in boys than in girls during puberty. Sex differences in urinary mast cell mediators remain unreported despite known sex-specific variations in eicosanoid pathways. https://loom.ly/exA7i_g

Other viruses beyond respiratory syncytial virus (RSV) and rhinovirus play a significant but underappreciated role in asthma inception and exacerbations. Learn more about these other respiratory bandits and earn CME: https://loom.ly/Dj3KirY

Wonder what your colleagues are reading in Annals? Take a look at the Most Read (Last 30 Days) section of the Annals homepage and find out! www.annallergy.org

Peanut has been implicated as the leading or among the leading causes of fatal anaphylactic reactions. Guidance emphasizes the importance of individualizing treatment and the potential for immunotherapy and omalizumab. www.annallergy.org/article/S108...

The September 2025 issue of Annals of Allergy, Asthma & Immunology focuses on respiratory viruses and asthma. Read the highlights: college.acaai.org/the-septembe...

The inclusion of tahini lip dose challenge may help improve diagnostic accuracy in the evaluation of sesame allergy, particularly in identifying patients at high/low risk. Learn more: www.annallergy.org/article/S108...

Decreasing long-term air pollution exposure and increasing allergen sensitization are associated with higher type 2/non-type 2 CRSwNP ratio, highlighting the role of environmental factors in endotype shifting. www.annallergy.org/article/S108...

Any therapy should meet 3 criteria—necessity, safety, and effectiveness. Only by continuing to revisit these are we able to provide the right care, at the right time, every time. Read "Your Money or Your Life!" www.annallergy.org/article/S108...

School season = respiratory virus season. Annals of Allergy, Asthma & Immunology focuses on respiratory viruses and asthma providing up-to-date info as the fall viral season (and asthma exacerbations) "falls" upon us! www.annallergy.org/current @annalsacaai.bsky.social #Medsky #asthma #virus

The most recent consensus guidelines recommend treating eosinophilic esophagitis with either proton pump inhibitors, swallowed topical steroids, diet elimination, or dupilumab. Learn more/earn CME: www.annallergy.org/article/S108...

Allergic symptoms, including food allergy and AD, frequently present early in IEIs and may precede infection susceptibility. Recognition of these pathways has enhanced diagnosis and led to targeted therapies. www.annallergy.org/article/S108...

The intranasal Schirmer test is a quick and inexpensive approach to determine secretion of the nasal mucosa. It is a promising tool for future integration into clinical practice to objectify nasal wetness or dryness. www.annallergy.org/article/S108...

After receiving venom immunotherapy (VIT), does the quality of life get better or worse for children with a potentially life-threatening allergy to honeybees and yellow jackets? Read more: www.annallergy.org/article/S108...

Although patients with severe asthma make up a fraction of the patients with asthma, severe asthma treatment contributes a high proportion to the total economic burden. Understanding patient characteristics and factors underlying severe asthma is a key priority. www.annallergy.org/article/S108...

In addition to pharmaceutical-grade options, the creation of standardized real-food sublingual immunotherapy protocols for use in real-world settings may allow more allergists to consider incorporation of SLIT in their own clinical practice. www.annallergy.org/article/S108...

Ethical considerations in food allergy management include addressing unknowns associated with long-term treatments, whether a child will outgrow their allergy, and the safety in using biologics. Learn more. www.annallergy.org/article/S108...

Oral Immunotherapy has exhibited great potential in the treatment of food allergy. There is no global consensus on best practices of OIT education. This study assesses ChatGPT accuracy as a self-guided educational resource for parents with children undergoing OIT. www.annallergy.org/article/S108...

The August issue of Annals of Allergy, Asthma & Immunology is here! Everything about #EosinophilicEsophagitis #EoE -- check it out and provide your patients with the most up-to-date care in #allergy and #immunology! @annalsacaai.bsky.social #MedSky #eosinophils #ImmunoSky www.annallergy.org/current

This yardstick provides the clinician with a review of available therapies to treat mast cell activation syndrome and indolent systemic mastocytosis and an evidence-based expert opinion approach regarding how best to utilize these therapies. www.annallergy.org/article/S108...

If you are a Fellow-in-Training who has published a print article in Annals of Allergy, Asthma & Immunology between 7/1/24-6/30/25, you are eligible for the FIT Awards! You must be nominated - find out more here: loom.ly/r741zkw

The choice of a biologic may be based on administration frequency, safety, and comorbidity treatment but is often heavily influenced by phenotype- and biomarker-directed clinical efficacy. Learn how weighing real-world studies can accurately reflect outcomes in clinical practice. bit.ly/4nZu3ad

If you are a Fellow-in-Training who has published a print article in Annals of Allergy, Asthma & Immunology between 7/1/24-6/30/25, you are eligible for the FIT Awards! You must be nominated - find out more here: loom.ly/r741zkw

Patients with chronic rhinosinusitis with nasal polyps comorbid with asthma often experience poor outcomes after endoscopic sinus surgery. Learn how this study evaluated the impact of asthma severity on the long-term outcomes after surgery in these patients. www.annallergy.org/article/S108...

Nominate a Fellow-in-Training author for a FIT Award! If you know a FIT who has published a print article in Annals between 7/1/24-6/30/25, they are eligible for the FIT Awards. Find out more here: college.acaai.org/acaai-annals...

A study investigates the association between body fat percentage and steroid sensitivity in patients with asthma and clarifies the potential mechanisms underlying this association. Is there a potential therapeutic approach for this population? Learn more: www.annallergy.org/article/S108...

Annals provides state-of-the-art recommendations on the use and interpretation of serum tryptase in clinical practice. This review explains the basic, clinical, and technical context of tryptase and how new research is driving clinical utility. www.annallergy.org/article/S108...

If you are a Fellow-in-Training who has published a print article in Annals between 7/1/24-6/30/25, you are eligible for the FIT Awards! You must be nominated - find out more here: college.acaai.org/acaai-annals...

On Instagram, @farah.khan.md posted about Annals' article on Ethics in Food Allergy Management. "But just like there is no one single perfect diet for everyone, there is no single right way to manage everyone with a food allergy. We have a menu to pick from now." www.instagram.com/p/DLYVodfvG7...

The July issue of @annalsacaai.bsky.social (Annals of Allergy, Asthma & Immunology) is now available. Our focus is an update on rhinitis -- learn new and impactful information to provide the best care to your patients. #MedSky #Allergy www.annallergy.org/current

Chronic cough (CC) in adults is defined as a cough lasting more than 8 weeks, with a global prevalence of approximately 10%. Learn about potential causes, different types of CC, management and treatment in this new review. www.annallergy.org/article/S108...