Another Oral small-molecule GLP-1 RA, HRS-7535, being studied for Type 2 Diabetes - phase 2 trial in those Inadequately Controlled With Metformin jamanetwork.com/journals/jam...

Universally Screening Children for Early-Stage Type 1 Diabetes may be appropriate based upon this population trial. What do you think? jamanetwork.com/journals/jam...

A comparison of the effects of tirzepatide and dulaglutide on major kidney events in people with type 2 diabetes: pre-specified exploratory analyses of the SURPASS-CVOT trial - The Lancet Diabetes & Endocrinology www.thelancet.com/journals/lan...

Happy Mother’s Day 💐 This day is still a tough one for us after losing our mom—but it’s also a reminder of how much moms give, every single day. @drnadolsky.bsky.social

Causes of Excess Deaths in the US Compared With Other High-Income Countries: 1️⃣circulatory diseases (ie heart disease) ➡️Drug poisonings, alcohol, and suicide accounted for 24% of the increase in excess US deaths overall and #1 for ages 0 to 44 years. jamanetwork.com/journals/jam...

Replace Yourself With AI, CEO Katz www.medpagetoday.com/opinion/seco... In 1970, there were far more physicians in the U.S. than healthcare executives or managers. By 2009, administrators outnumbered physicians by more than 10 to one.

In this post hoc analysis of participants in the SURMOUNT-1, -3, and -4 trials receiving at least 1 concomitant weight-inducing medication (17.3%-20.0%), tirzepatide treatment was associated with comparable weight loss to the primary study results. jamanetwork.com/journals/jam...

Obesity and Cancer: A Translational Science Review url: jamanetwork.com/journals/jam...

Throwback to origins of #DocsWhoLift Brothers Live Lifestyle Medicine www.medpagetoday.com/primarycare/... @DrNadolsky

In this cohort study of 17 288 patients, the use of GLP-1 RAs was associated with significantly lower risks of limb events, amputation, cardiovascular events, progression to dialysis, and all-cause mortality compared with DPP-4 inhibitors. : jamanetwork.com/journals/jam...

Politics used to be about debating different and/or opposing views, ideas and principles of governance. These day, it feels more like tribalism—where loyalty to team matters more than honor, consistency, truth, facts or even obvious right and wrong.

Water no better than diet beverages in head to head trial for type 2 diabetes (trended worse actually) PMID: 41369640

Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies - The Lancet www.thelancet.com/journals/lan...

Menopause hormone therapy and risk of mild cognitive impairment or dementia: a systematic review and meta-analysis - The Lancet Healthy Longevity www.thelancet.com/journals/lan...

Discordance Between Online Information and Male Hypogonadism Clinical Guidelines: A Global Multilingual Content Analysis url: academic.oup.com/jcem/article...

Nutrition Policy Rang Hollow in 2025 www.medpagetoday.com/opinion/seco...

Dr. Garvey & I had a nice discussion about our recently published AACE consensus algorithm on medical evaluation and management of obesity with @physicianswkly. Check it out here! www.physiciansweekly.com/podcast/insi....

Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes | @nejm Superior weight and glycemic benefits Not quite statistically significant superior MACE benefits (non-inferior) Lower incidence of death www.nejm.org/doi/full/10....

#CGM use was associated with a significantly lower risk of all-cause hospitalization and mortality, while associations with glycemic outcomes varied in this cohort of insulin-treated older adults with #Alzheimer disease and related dementias (ADRD) and #diabetes jamanetwork.com/journals/jam...

We all recommend reducing restaurant food, but that’s not good politics. “Restaurants have typically escaped scrutiny, despite providing roughly 1 in 4 calories consumed and having the worst average nutritional quality of any food source in the US” MAHA jamanetwork.com/journals/jam...

Non-coeliac gluten sensitivity - The Lancet www.thelancet.com/journals/lan...

The effects of antidepressants on weight, cardiometabolic and other physiological parameters: a systematic review and network meta-analysis - The Lancet www.thelancet.com/journals/lan...

Continuous Glucose Monitoring Frequency and Glycemic Control in Type 2 Diabetes CGM may be unhelpful for healthy people without blood sugar dysregulation, but VERY helpful for type 2 #diabetes jamanetwork.com/journals/jam...

Good news: Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 | @nejm.org www.nejm.org/doi/full/10....

Liraglutide and Weight Loss Among Suboptimal Metabolic Bariatric Surgery Responders: jamanetwork.com/journals/jam...

The premise of #MAHA has always retained widespread support but, unfortunately, political agendas seem to prevail. #health

Cardiometabolic Outcomes Among Adults With Abdominal Obesity and Normal BMI: jamanetwork.com/journals/jam...

Wonder why people are so disenfranchised by partisan politics? Just watch @SpeakerJohnson & @RepJeffries on @ThisWeekABC Health insurance does NOT 🟰 healthcare and is actually the racket/scam driving healthcare dysfunction

Be careful this #Halloween! 1️⃣ Yes, observational data still correlate diet soda with obesity and related disease. Correlation does NOT equal causation 2️⃣ Interventional trials consistently show benefit of diet soda replacing sugary soda for #WeightLoss and #health - meaningful data PMID: 34481971

I honestly don’t understand how the politicians can just fight about access to health insurance when it seems to me that the U.S. healthcare system’s dysfunction is rooted less in access to insurance and more in how the insurance system itself operates. ⸻

Another trial supporting artificial sweeteners over sugary consumption; after weight loss, randomized showing better maintenance with prolonged consumption of S&SEs in a healthy diet is a safe strategy for obesity management. doi.org/10.1038/s422...

Health insurance - they don’t just deny coverage of necessary therapy for patients. ➡️Referral to endocrine for elevated estrogen in a male. 👌We eval and submit claim 🖕insurance denies paying us because males don’t have high estrogen 🤦🏼

Tylenol's Tweet on Pregnancy Use Shared by the White House Out of Context The 2017 tweet appears to be a canned customer service response to a since-deleted post from a presumed customer." www.medpagetoday.com/obgyn/pregna...

The United States has swiftly retreated from global health leadership. In @lemonde.fr, I share why this retreat will have serious repercussions worldwide.

Dr Robert Lustig gets Fact-checked by MD PhD Doctor Lustig´s views on sugar, saturated fat, heart disease, LDL and much more get examined for their scientific accuracy https://youtu.be/vdoDx9dIuNE

Exercise: consistency over complexity. Most people just need to stick with the fundamental on a consistent basic for health benefits from aerobic (ie walking, swimming, biking) and resistance training. 💪🏽❤️

FDA Takes Aim at Hims & Hers, Weight-Loss Drugs in New Advertising Blitz www.medpagetoday.com/practicemana...

The US is one of only 2 countries worldwide that permits direct-to-consumer pharmaceutical advertising. The patient-doctor relationship has been distorted, creating increased demand for medications regardless of clinical appropriateness.

Posting about health/wellness & medical information feels futile after the assassination + another school shooting yesterday. Fighting online misinformation triggers people in this divisive political environment these days too so let’s spread love. We are all human ❤️

Compared with Roux-en-Y gastric bypass, single anastomosis duodeno-ileal bypass with sleeve gastrectomy was superior for weight lossopens in a new tab or window after 2 years, a randomized trial found. www.thelancet.com/journals/lan...

@RFKJr_Official- “Trusting the experts is not a feature of either a science or democracy.” 🤦🏼 You wouldn’t board a plane and say, “I don’t trust pilots, I’ll fly it myself.” Why should public health, engineering, or climate be any different?

Patients initiating semaglutide or tirzepatide had a more than 40% lower risk of hospitalization for heart failure or all-cause mortality compared with sitagliptin (DPP-4inh). jamanetwork.com/journals/jam...

Teva Pharmaceutical Announces FDA Approval and Launch of Generic liraglutide (“Saxenda®) injection– First Generic GLP-1 Indicated for obesity ir.tevapharm.com/news-and-eve...

Secondary Prevention of Atherosclerotic Cardiovascular Disease | review

Since influencers (and sadly, docs) are selling creatine in pink packaging upselling to women 👛, I’ve decided to make special packages of creatine at higher cost for type 1 diabetes and other endocrine disease states 😂

In type 2 #diabetes + #kidney disease, benefits of semaglutide (#ozempic) on kidney outcomes, #heart outcomes, & death were observed regardless of baseline mineralocorticoid antagonist use (meds that block the adrenal blood pressure hormone, aldosterone). doi.org/10.2337/dc25...

I don’t know who needs to hear this, but organic shit is still, “shit.”

My simple way of explaining to patients of why exercise is so important metabolic health, including #diabetes, etc, is describing your muscle cells as sugar/fat burning factories. Building and exercising your muscles is key for metabolic #health #exercise #muscle #DocsWhoLift

“I feel like myself again!” Common quote from patients in endocrinology clinics after starting menopausal hormone therapy (MHT) or other hormone replacement therapies (#HRT) for deficiencies (ie #thyroid, #adrenal, #testosterone, etc).

If it tastes better, fine, but if we want to make it healthier, make it a diet. #maha #health #sugar