Swantje Lenz
@swlenz.bsky.social
📤 201
📥 117
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PostDoc at MPI-CBG, von Appen and Toth-Petroczy groups
reposted by
Swantje Lenz
Mathilda Lennartz
about 2 months ago
I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you:
www.nature.com/articles/s41...
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Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology
Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...
https://www.nature.com/articles/s41556-026-01915-x
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reposted by
Swantje Lenz
Mihaly Badonyi
2 months ago
My first manuscript in MPI colours! With
@tothpetroczylab.bsky.social
, we show that AlphaFold PAE-derived contact probabilities are well calibrated to the fraction of true interface contacts across experimentally determined protein dimers.
www.biorxiv.org/content/10.6...
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reposted by
Swantje Lenz
André Nadler
9 months ago
Out today in
@nature.com
: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
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Happy to share the first paper of my postdoc and happy to have been part of the team!
add a skeleton here at some point
about 1 year ago
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reposted by
Swantje Lenz
André Nadler
about 1 year ago
Are lipids actively sorted during clathrin mediated endocytosis like proteins?
@mathilda95.bsky.social
addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow.
www.biorxiv.org/content/10.1...
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reposted by
Swantje Lenz
CrowDsourcing COndensate Database & Encyclopedia
about 1 year ago
🍃CD-CODE update v1.09 is here!🍃 👀Check out the new
#biomolecular
#condensates
at
cd-code.org
👀We're continuing to update
#Protein
-
#condensate
connections and resolve issues! Join us to share your
#condensate
#expertise
as a contributor:
cd-code.org/signup
#Bioinformatics
#DatabaseUpdate
#IDR
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reposted by
Swantje Lenz
André Nadler
over 1 year ago
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by
@mathilda95.bsky.social
changes that.
www.biorxiv.org/content/10.1...
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reposted by
Swantje Lenz
Toth-Petroczy lab
over 1 year ago
Our PICNIC tool predicts condensate-proteins regardless of their structural disorder across organisms
@naturecomms.bsky.social
. Congratulations to
@annaha-poetry-art.bsky.social
for developing the algorithm and to Hari
@hymanlab.bsky.social
for the experiments!
www.nature.com/articles/s41...
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PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms - Nature Communications
Here the authors report PICNIC (Proteins Involved in CoNdensates In Cells), a machine learning algorithm that predicts approximately 40–60% of proteins form condensates in various organisms, showing n...
https://www.nature.com/articles/s41467-024-55089-x
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