@shalevitzkovitz.bsky.social
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Happy to share our new preprint: Spatial Rewiring of Enterocyte Identity in Celiac Disease. We describe unexpected changes in enterocyte zonation in Celiac Disease.
27 days ago
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Happy to share our new preprint: Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics:
www.biorxiv.org/content/10.1...
We utilize VisiumHD to extract intra-cellular mRNA polarization patterns in epithelial tissues.
6 months ago
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reposted by
Igor Ulitsky
11 months ago
New preprint ๐ from @AlanMonziani in the lab โ EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology
www.biorxiv.org/content/10.1...
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EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology
Mammalian genomes are pervasively transcribed into long noncoding RNAs (lncRNAs), whose functions and modes of action remain poorly understood. EPB41L4A-AS1 is an evolutionary conserved, broadly and h...
https://www.biorxiv.org/content/10.1101/2025.04.08.647803v2
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Happy to share our new preprint: A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver:
www.biorxiv.org/content/10.1...
about 1 year ago
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reposted by
Shai Bel (The Mucus Man)
over 1 year ago
What a cool new story by
@shalevitzkovitz.bsky.social
! They show which proteins and RNAs are expressed in the apical vs basal sides of intestinal epithelial cells (mice and humans). Some really interesting phenomenons
@plosbiology.bsky.social
@npariente.bsky.social
journals.plos.org/plosbiology/...
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Intracellular polarization of RNAs and proteins in the human small intestinal epithelium
The intestinal epithelium is a polarized monolayer of cells and both proteins and mRNAs have been shown to have global basal-apical polarization in mice. These authors perform a systematic analysis of...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002942#sec027
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