Angela Casini
@medbioinorgchem.bsky.social
๐ค 1435
๐ฅ 146
๐ 93
Chemist, European, Academic
reposted by
Angela Casini
Royal Society of Chemistry
6 days ago
Want to discuss your latest research on imaging, biosensing and diagnostics research? Thereโs still time to join us at the Chemical Science symposium 2025 and present your work alongside peers and leading experts. Submit an abstract: rsc.li/chemscisymp2025 #ChemSky
@chemicalscience.rsc.org
#ChemSky
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Great EU COST LUCES workshop organized by Dr
@apoethig.bsky.social
and Prof
@lrraurell.bsky.social
at the CRC on supramolecular interactions and photophysical properties! Thanks for the wonderful science and discussion!
@gmalcantar.bsky.social
and Elisabeth Klaus gave excellent presentations ๐ค
6 days ago
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Thanks for this nice memory!! ๐ค
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14 days ago
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A fantastic end of the international symposium in Bioinorganic chemistry organized by Prof Ela Gumienna-Kontecka in Wroclaw!! Thanks for the wonderful time and โฆ till the next one ๐๐ค๐ฅRudi Fasan Gabriele Meloni David Giedroc Norah Barba
@borisvauzeilles.bsky.social
@giedroclab.bsky.social
15 days ago
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A great event for science and friendship ๐ค thanks to the organizers for the invite and the hospitality!
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18 days ago
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With one of my soulmates in Bioinrganic chemistry, Prof Ivana Ivanovic-Burmazovic at the 7th EuChems Inorganic Chemistry conference in Belgrade! ๐ค๐ Technical University of Munich and Ludwig-Maximilians-Universitรคt Mรผnchen rock together!! ๐
21 days ago
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The 7th EuChems Inorganic Chemistry conference is about to start in Belgrade!!! Lovely to meet Prof. Sanja Grguric-Spika again ๐ค
21 days ago
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The Fabulous 6 SMARTdrugs _ PIs Tim Witney Jason Holland Alex Poot Jordi Llop Miguel Castanho and myself in London together with one of their external advisors, Prof Kevin Brindle from Cambridge and TUM IAS fellow ๐ค๐ฅcredit to ChatGPT powered by Jordi Loop AI ๐
23 days ago
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The 2nd annual meeting of our EIC Pathfinder Open network SMARTdrugs _ is in full swing at KCL hosted by Tim Witney and featuring Jason Holland Jordi Llop Alex Poot Miguel Castanho and colleagues. All this in a sunny London ๐ Here a few pics of the evening on the terrace of the
#LIHE
24 days ago
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Kicking off the 3rd day at ISBOMC with the fantastic plenary lecture of Maria Contel
@contellab.bsky.social
on her journey through gold chemistry for anticancer drug discovery!! ๐ค I particularly loved her work on antibody-drug conjugates ๐๐ป๐๐ป๐๐ป๐๐ป๐๐ป๐๐ป
about 1 month ago
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What a day!!! ๐๐ค
@gmalcantar.bsky.social
@contellab.bsky.social
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about 1 month ago
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Excellent Start of ISBOMC in Paris! First day featuring many great presentations like the one of
@conchitagimeno.bsky.social
and get together with former PhDs and friends in organometallic chemistry! Thanks to
@gassergroup.bsky.social
and
@cariouk.bsky.social
for the organization!! ๐ค๐ฅ
about 1 month ago
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Proud of this new preprint on ML-assisted Computational Workflow to the Robust Modeling of Supramolecular Metallacages in Solution | ChemRxiv -
doi.org/10.26434/che...
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ML-assisted Computational Workflow to the Robust Modeling of Supramolecular Metallacages in Solution
We present here an integrated computational workflow to study the behavior of selected self-assembled [Pd2L4]4+ metallacages in explicit solvents (water and DMSO) and benchmark them for future in sili...
https://doi.org/10.26434/chemrxiv-2025-zt4jf?utm_campaign=shareaholic&utm_medium=bluesky&utm_source=socialnetwork
about 1 month ago
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Today is a good day for the results on organogold compounds in medicine! This paper concerns the 1st Gold-PROTAC investigated in a degradome assay developed by the group of Sam Meier-Menches! the study is in the frame of our
#UbiQancer
CRC TRR network โค๏ธ
chemrxiv.org/engage/chemr...
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A Gold-PROTAC degrades the oncogenic tyrosine kinase MERKT: insights into the degradome from a steady-state system
Targeted protein degradation is a valuable strategy to eliminate disease-relevant proteins. Among other classes, proteolysis targeting chimeras (PROTACs) are bifunctional molecules that induce the pro...
https://chemrxiv.org/engage/chemrxiv/article-details/68989f7f728bf9025edad3aa
about 2 months ago
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Our new toy ๐
@gmalcantar.bsky.social
@iiribarren.bsky.social
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about 2 months ago
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New Master student Sophia Ling starting her project on FAPi radiohybrid compounds for theranostics! ๐คโค๏ธ
about 2 months ago
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Interested in New Trends in Mass Spec Imaging of proteins in cancer tissues? Check this preprint out ;-) A small molecule drug-based Ru(II) polypyridine mass-tag for multimodal imaging of tissue samples | ChemRxiv -
doi.org/10.26434/che...
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A small molecule drug-based Ru(II) polypyridine mass-tag for multimodal imaging of tissue samples
Mass spectrometry imaging (MSI) is a powerful tool for spatially resolved multi-omics analysis of tissue samples in clinical research. However, its proteomics application is still limited due to chall...
https://doi.org/10.26434/chemrxiv-2025-hp7rl?utm_campaign=shareaholic&utm_medium=bluesky&utm_source=socialnetwork
about 2 months ago
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This! ๐
2 months ago
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Great time in Pisa at the 2025 Chemistry for the Future conference in the last few days!! And an excellent organization by the PhD students of the Department of Chemistry ๐๐ป๐๐ป๐๐ป Thanks for the invite ๐คhttps://cff.dcci.unipi.it
3 months ago
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Proud of my student Franziska Schuderer that today defended her PhD thesis achieving Magna Cum Laude for her work on BBB translocating radiotracers targeting glioblastoma. Well done Franzi!!! ๐ค๐๐ฅโค๏ธ
3 months ago
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Great to receive the visit of Prof Maria Contel
@contellab.bsky.social
and learning on her advancements on antibody/metallodrug conjugates for cancer treatment!!! We look forward to having you back next year ๐ค
3 months ago
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Check out our latest study on Pd-cages for dual-modality imaging including cool MS analysis and fancy in ovo PET imaging,
doi.org/10.1039/D5QI...
Congrats to Marike Drexler, Luisa Ronga, Ioannis Kanavos,
@gmalcantar.bsky.social
Daniela Kraus
@timwitney.bsky.social
! EIC Pathfinder
#SMARTdrugs
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Design of porous self-assembled homoleptic and heteroleptic Pd2+ cages incorporating silicon-based fluoride acceptors: the way towards nuclear imaging applications
Supramolecular self-assembly is a promising tool to develop multifunctional theranostic agents and has recently entered the field of radiochemistry. In this work, lantern-shaped [Pd2L4]4+ metallacages...
https://doi.org/10.1039/D5QI01092F
4 months ago
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This is where everything began for a real boost of my academic career as a TUM IAS fellow between 2016-19!!! Thank you for all your support and to make me part of the IAS community!
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4 months ago
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Certain days are really great ๐ค thanks Steffi Ludwig for the visit and beautiful flowers.
4 months ago
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Great to have Prof Janet Morrow as guest today! So many open questions on the host-guest chemistry of metallacages based on Fe(III) and on what makes them excellent contrast agents! โฆ But the future of self assembled imaging agents is bright ๐ค
4 months ago
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Extremely honoured to have our work on supramolecular radiopharmaceuticals highlighted in the latest news in Nature Biotechnology!!! Thank you to the EIC Pathfinder SMARTdrugs
@timwitney.bsky.social
@hollandlab.bsky.social
Alex Poot (UMCU)
@cicbiogune.bsky.social
Jordi Llop !
rdcu.be/emCW6
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Biopharma dives into tumor-seeking radioactive drugs
Nature Biotechnology - Big pharma and investors are piling into the precision radiation space as the next generation of increasingly potent targeted ฮฑ-particle therapies promises to destroy...
https://rdcu.be/emCW6
4 months ago
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At the end of a Golden conference with friends, Sophie Thomas @sophierthomas.bsky.social , Cider ๐บ and Chorizo โฆ ๐๐๐ฅ
@lrraurell.bsky.social
@conchitagimeno.bsky.social
5 months ago
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Laura
@lrraurell.bsky.social
rocking at the Gold conference 2025 ๐๐
5 months ago
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Excellent start of the Gold 2025 conference in San Sebastiรกn/ Donostia! Stay tuned if you want to know everything about gold that you always dreams of ๐
@sophierthomas.bsky.social
@reithoferlab.bsky.social
5 months ago
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It was a really great event!!! Thank you to the students for the invite to the Long Night of the Universities in Munich, where I could talk about Medicinal Inorganic Chemistry and of our EIC network SMARTdrugs _! Here a pic with students and with colleague Helge S. Stein ๐
5 months ago
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25 April, Liberation day in Italy! festa della liberazione dal Fascismo in Italia! ๐ฎ๐น This day is also dedicated to my grandfather Giovanni, a partisan!!! โค๏ธ
5 months ago
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Almost ready for the show! ๐ the Long night of the Universities is approaching ๐ค๐
gaf.fs.lmu.de/long-night-o...
5 months ago
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Happy Easter ๐ฃ๐๐ฅ
5 months ago
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reposted by
Angela Casini
Dori G Quiroga
5 months ago
www.sciencedirect.com/science/arti...
. Please enjoy Easter brake with our last contribution.
#chemistry
#chembiology
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Antiproliferative activity in breast cancer cells of PtL2: A steroid-thiosemicarbazone platinum(II) complex
Breast cancer remains one of the most diagnosed cancers in women worldwide. Metallodrugs such as cisplatin are used in advanced stages and hormone indโฆ
https://www.sciencedirect.com/science/article/pii/S0162013425001035
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A dream came true with this manuscript: we use N-heterocyclic carbene complexes to stabilise radioactive 198Au(I) for radiopharmaceutical applications! Featuring
@sophierthomas.bsky.social
Prof. Sarah Spreckelmeyer and fantastic collaborators! Happy Easter everyone ;-)
chemrxiv.org/engage/chemr...
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N-Heterocyclic Carbenes as Ligands to 198Au(I) Radiolabeled Compounds: a New Platform for Radiopharmaceutical Design
The application of Au(I) ions in pharmaceuticals, including in nuclear medicine, is limited by their instability towards reduction in vivo. The gold radionuclide 198Au with a half-life of 2.7 days emi...
https://chemrxiv.org/engage/chemrxiv/article-details/67fd4f786dde43c908e3d661
5 months ago
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Gold rocks ;-)
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6 months ago
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It a been a success our Student-led Symposium Metals in Medicine!! ๐ค๐ฅ thank you to all the invited speakers
@atenasolea.bsky.social
@boekhovenlab.bsky.social
@apoethig.bsky.social
Celia Bonnet and Stefano Leoni! Special plause to Marike Drexler who took care of all the organizational details ๐๐
6 months ago
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Completely agree ๐ค
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6 months ago
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Proud to be part if the Ubiqancer network! Check out project B03 ๐https://ubiqancer.de/
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ubiqancer | CRC/ Transregio TRR 387
https://ubiqancer.de/
6 months ago
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So proud of the highlight of our new Si-F based acceptor (SiFA) by the Editorial board of EJNMMI Radiopharmacy and Chemistry ;-) Congratulations to Sebastian Fenzl, Sandra Dominelli , Marike Drexler Prof. Shige Inoue, and
@timwitney.bsky.social
ejnmmipharmchem.springeropen.com/articles/10....
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Highlight selection of radiochemistry and radiopharmacy developments by editorial board - EJNMMI Radiopharmacy and Chemistry
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development and app...
https://ejnmmipharmchem.springeropen.com/articles/10.1186/s41181-025-00335-w
6 months ago
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Thanks to all my friends, coworkers and students for making my birthday a special day yesterday!! ๐ค๐๐
6 months ago
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Extremely proud to host a new Humboldt Fellow in our group starting in the next months! Dr Moumita Maji will work on antibody-metallodrugs conjugates bringing new chemistry ๐งช in our group ๐ค
6 months ago
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Check out our SMARTdrugs website for updates on cool supramolecular radiopharmaceutical design Folks! ;-)
@timwitney.bsky.social
smartdrugs2024.com
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smartdrugs2024.com
https://smartdrugs2024.com
6 months ago
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Thank you Max for fostering the interactions amongst us and leading us to this success!! ๐๐ป๐๐ป๐
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6 months ago
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Great dinner yesterday with
@thebabaklab.bsky.social
Nick Long, Bengang Xing and Gary in Hong Kong ๐ญ๐ฐ looking forward to the next time ๐
6 months ago
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Science talks in Hong Kong ;-)
7 months ago
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So honoured to be part of this outstanding lineup of speakers!! Thanks to the organisers for the invite! Let's talk about the future of Med Chem together!
www.lsccb-lc2025.com
7 months ago
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We have plans here in Singapore!! stay tuned folks ๐
7 months ago
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What can I say!?! I minionised them all ๐คฃ๐ซฃ๐ค
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7 months ago
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Bologna has treated me well the last days!!! Met great people and loved the city ๐ค
7 months ago
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