This study shows that DNA-mismatch-repair-deficient cell populations maintain high growth rates despite a high SNV burden of at least 50,000 mutations per cell. In these cells, the INDEL burden plateaus at approximately 16,000 per cell. doi.org/10.1016/j.xi... #SomaticMutations #CellularAging

This review discusses the application, challenges, and future development directions of artificial intelligence in various branches of life sciences, including zoology, plant science, microbiology, biochemistry...... doi.org/10.59717/j.x... #lifesciences #artificialintelligence #research

This review underscores the importance of a multifaceted approach to obesity management, aiming to curb the escalating trend and enhance future interventions and treatments. Read more doi.org/10.59717/j.x... #medicine #obesity #healthylifestyle

This review explores the opportunities and challenges posed by AI in modern medicine, highlighting its applications in precision healthcare, phenomics, early diagnostics, and personalized treatment. Read more doi.org/10.59717/j.x... #medicine #artificialintelligence #healthcare #research

In this review, Xiao et al. discuss recent advancements in our understanding of DC biology under homeostatic conditions and within the tumor microenvironment with a particular emphasis on insights gained through single-cell multi-omics. doi.org/10.59717/j.x... #Medicine #DendriticCells #research

This perspective summarizes the characteristics of altered follicular fluid iron content and oocyte quality in EMs-associated infertility patients, along with detection methods and correlative studies. Read more doi.org/10.59717/j.x... #medicine #research #ReproductiveHealth

In this review, Zhai et al. introduce the conditions of the gut microbiome in COVID-19 and how it gradually develops in PCS patients, and its possible mechanisms influencing the main symptoms of PCS patients. Read more doi.org/10.59717/j.x... #medicine #microbiome #postcovid

Li et al. describe the common molecular mechanisms or organelles of exosome biogenesis and autophagy in cells, as well as the potential implications of exosomes regulating autophagy in diseases after internalization by target cells. doi.org/10.59717/j.x... #lifesciences #exosome #research #TIC2025

This review will introduce the common types of sports injuries, traditional clinical strategies and explore the current application status of regenerative medicine in sports injuries. Read more doi.org/10.59717/j.x... #medicine #sportsinjury #research

Great News! On May 15, 2024, The Innovation Life (ISSN: 2959-8761) was officially indexed by the Scopus database! We extend our sincere gratitude to our dedicated authors, reviewers, editors, and incredible readers for their invaluable contributions and unwavering support. #news #Science #research

This commentary delves into the nuances the DO-HEALTH trial's findings and their broader implications for aging research and public health. Read more doi.org/10.59717/j.x... #Medicine #aging #PublicHealth #TIC2025

Check out the latest issue of The Innovation Medicine!!! Volume 3, Issue 1 is now online! www.the-innovation.org/medicine/art... #medicine #research #Clinicaltrial #obesity #Lupus #CART #artificalintelligence #diabetes #vaccines #epigenetics #EHR #diseases #inflammation #antifungal #LungCancer

In this Perspective, Zhou et al. briefly introduce the general concepts of AI and organoids/OoCs, explore their state-of-the-art applications in DDD, and discuss why and how their synergistic impacts can revolutionize the R & D of new drugs. doi.org/10.59717/j.x... #lifesciences #AI #Research

Check out the latest issue of The Innovation Life!!! Volume 3, Issue 1 is now online! www.the-innovation.org/life/article... #lifesciences #circulation #molecularbiology #microbiome #genetics #epigenetics #genomics #technology #Bioinformatics #organoid #Research

This study demonstrates that ZSH-512 effectively inhibits CSC-mediated tumorigenesis and metastasis through its epigenetically modulating stemness pathways, primarily via the RARγ-KDM3A axis. Read more doi.org/10.1016/j.xi... #medicine #research #CancerResearch

By examining the entire process of multimodal information fusion, we can gain deeper insights into AI’s working mechanisms and enhance our understanding of AI perception in complex environments. Read more doi.org/10.1016/j.xi... #ArtificialInteligence #research

In the near future, the application of single-atom catalysts is expected to extend to other photoelectrodes , further boosting the practical application of photoelectrochemical water splitting systems. Read more doi.org/10.1016/j.xi... #catalyst #research

Xu et al. commented on a recent study that explored the formation and retention mechanisms of epigenetic obesity memory at the gene expression level, offering systematic and comprehensive insights into the #epigenetic mechanisms underlying #obesity and weight cycling. doi.org/10.59717/j.x...

By leveraging advanced technologies, fostering interdisciplinary collaboration, adhering to the highest standards of evidence generation, traditional Chinese #medicine could transition from a traditional practice to a scientifically validated discipline. doi.org/10.59717/j.x... #Research #Clinical

He et al. introduced chimeric antigen receptor (CAR) T-cell therapy for #pediatric patients with refractory systemic lupus erythematosus, demonstrating promising #clinical outcomes and significant societal impact. doi.org/10.59717/j.x... #medicine #systemiclupuserythematosus #Research

Wang et al. summarize the strategies and limitations of current drug development methods and explore innovative approaches for creating effective antifungal therapies. Read more doi.org/10.59717/j.x... #Medicine #research #antifungal

This study pioneers a multi-stage deep learning model for pediatric tooth segmentation, classification, and treatment planning, with a focus on predicting tooth germ staging. Read more doi.org/10.59717/j.x... #Medicine #research #ArtificialIntelligence #pediatric

Sun et al. commented on a recent study that introduced an oriented monolayer polyhedral (OMP) membrane with a high-density arrangement of MOF particles, optimized for separating aromatic and aliphatic hydrocarbons in naphtha. Read more doi.org/10.59717/j.x... #MaterialsScience #AdvancedMaterials

No matter what the future of room temperature superconductors (RTS), the pursuing for RTS requires the spirit of exploration, endeavor and curiosity in science, it will certainly change our world and knowledge forever. Read more doi.org/10.59717/j.x... #materials #superconductors #technology

This study shows that higher glycogen deposition occurs in the liver but not in the muscle on GD 60 in low-body-weight fetuses. Abnormal deposition of glucose in the liver, which is required for fetal development at mid-gestation, may lead to retarded fetal growth. doi.org/10.59717/j.x... #research

HPV Self-Collection for Cervical Cancer: Dr. Kay’s Insights oncodaily.com/dialogues/24... #Cancer #CancerResearch #CervicalCancer #HPV #Medicine #Health #CancerPrevention #Oncology #OncoDaily

In this study, Ni et al. investigated bacterial and methanogenic community composition and methanogenic metabolic pathways in the shallow, middle, and deep depths within a 2-km profile of Quaternary saline lacustrine source rocks in the Qaidam Basin using metagenomic analysis doi.org/10.59717/j.x...

Research on Human metapneumovirus infection remains limited. While progress in vaccine development is promising, further advancements in this field will be crucial for preventing and controlling major respiratory #virus infections. doi.org/10.59717/j.x... #Medicine #vaccine #disease

This study reveals that RA not only increases the odds ratio of neuropsychiatric disorders but also impacts gray matter volume and brain activity. These findings underscore the importance of vigilant monitoring of the neuropsychiatric system in RA patients doi.org/10.59717/j.x... #Medicine #research

This review provides a systematic overview of the development understanding of BALF, discusses its possible applications in clinical diagnosis, prediction, and intervention, and highlights the role of emerging omics technologies in deciphering BALF. doi.org/10.59717/j.x... #Medicine #research

New in The Innovation Life! Merlin condensates A solid foundation for the Hippo signaling pathway. Wang et al. discuss the role of solid-like Merlin condensates in activating the Hippo signaling pathway and review other biomolecular condensates involved in this pathway. doi.org/10.59717/j.x...

New in The Innovation Life! The detection, function, and therapeutic potential of RNA 2'-O-methylation. Wu et al. provide a comprehensive overview of the methods employed to detect 2'-O-methylation in RNAs. Read more doi.org/10.59717/j.x... #LifeSciences #methylation #RNA

This study delves into the challenges of large-scale renewable energy development planning in China and explores how to leverage big data and spatial information #technologies to construct high spatiotemporal resolution models for large-scale #renewable #energy layout... doi.org/10.59717/j.x...

Yuan et al. find that the frozen duration decreased on average by 0.17 days/yr since 1990 with the highest decrease of approximately up to 1.0 days/yr in parts of Belarus and Ukraine, followed by the Yukon region in Canada and Alaska. doi.org/10.59717/j.x... #geoscience #research #environment

The current-assisted catalytic strategy will disrupt some traditional concepts in thermal #catalysis and promote a deeper understanding of the catalysis field, which provides a new approach to achieving higher performance with less #energy consumption. doi.org/10.1016/j.xi...

Had an incredible time at the 2025 Lymphoma, Leukemia & Myeloma Congress Winter Conference! 🌎🔬 Grateful for the opportunity to learn from the world’s leading experts in hematology-oncology, engage in thought-provoking discussions, & connect with inspiring colleagues.

🌟 Women in Lymphoma: Shaping the Future of Care 🌟 🎙️ Episode 2 Premieres February 25 @ 7 PM EST! Join Dr. Kerry Savage (BC Cancer) & Dr. Neha Mehta-Shah (WUSTL) for an insightful discussion on T Cell Lymphomas—covering the latest advancements, challenges, and the future of treatment.

International Childhood Cancer Day 2025 oncodaily.com/blog/241710 #Cancer #ChildhoodCancer #ChildhoodCancerAwareness #Medicine #Health #OncoThon #CancerAwareness #KidsCancer #Oncology #OncoDaily

Please help me add more journals to this list go.bsky.app/QeUyDtp

Please watch this whole video about changing your expectations. We need everyone to show up IN PERSON to nationwide protests & congressional office visits. It will take sacrifice & be uncomfortable, getting us out of our daily routines of going to work, etc. www.instagram.com/reel/DGG7x60...

Dr. Vinod Balachandran, who received the Yvonne Award 2024, was named to The Washington Post’s Next 50 oncodaily.com/blog/243480 @washingtonpost.com @mskcancercenter.bsky.social #Cancer #Researcher #Medicine #Health #YvonneAward #Oncology #OncoDaily

New in The Innovation Materials! Advancement and functionalization of PAF-1 and its derivatives. This review explores the research progresses of porous organic framework materials, PAF-1 (PAF = porous aromatic framework) and its derivatives. Read more doi.org/10.59717/j.x... #materials #research

This study aims to combine evidence from a nationwide cohort study with animal toxicology experiments to elucidate the temporal relationship and biological explanation between ozone exposure and age-related macular degeneration. doi.org/10.1016/j.xi... #medicine #ozone #eyedisease #research

Exciting news! 🎉 Articles published in The Innovation Life, The Innovation Geoscience, The Innovation Materials, The Innovation Medicine, and The Innovation Energy are now officially included in the CAS (Chemical Abstracts Service) Content Collection! #Research #Innovation

A new issue of Cell is out, featuring the 4 winners of the Rising Black Scientists Awards. Their essays bring hope, inspiration and reinforce the importance of equity in science. Do take a moment to check them out: www.cell.com/cell/current @cp-cell.bsky.social

🚨 Innovating Cancer Care 🚨 📣We’re thrilled to spotlight the pioneering work of Global Leader & Keynote Speaker, 🌟 Dr. Arturo LoAIza-Bonilla MD 🌟—Systemwide Chief of Hematology-Oncology at St. Luke's Health System & CMO of Massive Bio! Presentation: www.onclive.com/view/artific...

New in The Innovation Materials! Progress in palladium-based bimetallic catalysts for lean methane combustion Towards harsh industrial applications. Kong et al. reviewed #research advancements in Pd-based bimetallic catalysts for lean methane combustion. doi.org/10.59717/j.x... #materials

New in The Innovation! Self-calibrating multiplexed microneedle electrode array for continuous mapping of subcutaneous multi-analytes in diabetes. The discrete microneedle array facilitating real-time monitoring of complex diabetic states. doi.org/10.1016/j.xi... #medicine #research #diabetes

New in @theinnovation.bsky.social! Famitinib plus camrelizumab in patients with advanced #colorectalcancer: Data from a multicenter, basket study. Ai et al. report the results of famitinib plus camrelizumab in patients with previously treated CRC. doi.org/10.1016/j.xi... #clinical #Immunotherapy