Victoria Aranda
@vicaranda.bsky.social
📤 2525
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Deputy Editor at Nature, Cancer, Biomedicine, Genetics and Biotechnology. All views my own.
reposted by
Victoria Aranda
Magdalena Skipper
6 months ago
154 million lives and counting: 5 charts reveal the power of vaccines - a timely news explainer/reminder by
@heidiledford.bsky.social
@nature.com
🧪
#MedSky
www.nature.com/articles/d41...
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reposted by
Victoria Aranda
Magdalena Skipper
6 months ago
Meet the MitoBrainMap! The first map of mitochondrial phenotypes provides a foundation for exploring the molecular energetic landscape of a normal brain. It turns out that the human brain contains diverse mitochondrial phenotypes driven by topology & cell types 🧪
www.nature.com/articles/s41...
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A human brain map of mitochondrial respiratory capacity and diversity - Nature
The ability to physically partition the human brain at a spatial resolution comparable to neuroimaging methods enabled the development of a brain-wide atlas of mitochondrial content, specialization an...
https://www.nature.com/articles/s41586-025-08740-6
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reposted by
Victoria Aranda
Magdalena Skipper
7 months ago
Our
#Scientistsatwork
photo competition is open for submissions. This is a competition for scientists themselves. Winners will receive £500, a subscription to Nature & have their photo featured alongside an interview in Nature. Deadline - March 28th
@nature.com
www.nature.com/immersive/sc...
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#ScientistAtWork photo competition
A celebration of the striking and colourful work that scientists do around the world.
https://www.nature.com/immersive/scientistatwork/index.html
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Victoria Aranda
Magdalena Skipper
7 months ago
How the NIH dominates the world’s health research — in charts (and what we stand to lose)
@nature.com
@natureportfolio.nature.com
🧪
www.nature.com/articles/d41...
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Victoria Aranda
Barbara Marte
7 months ago
new out in
@nature.com
www.nature.com/articles/s41...
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Clonal dynamics and somatic evolution of haematopoiesis in mouse - Nature
Isolating and studying haematopoietic stem cells in young and aged mice demonstrates evolutionary processes related to blood production and provides a framework for interpreting future work using labo...
https://www.nature.com/articles/s41586-025-08625-8?linkId=13271206
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Today in Nature, integrating AI in smart watches for loss of pulse detection:
www.nature.com/articles/s41...
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Automated loss of pulse detection on a consumer smartwatch - Nature
Nature - Automated loss of pulse detection on a consumer smartwatch
https://www.nature.com/articles/s41586-025-08810-9
7 months ago
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We at Nature denounce this assault on science 🧪
www.nature.com/articles/d41...
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Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
https://www.nature.com/articles/d41586-025-00562-w
7 months ago
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Victoria Aranda
Magdalena Skipper
7 months ago
Breast cancer is on the rise: data reveal drastic gap in survival rates Lack of screening and limited treatment options mean that low- and middle-income countries face higher death rates despite having fewer cases than wealthier nations 🧪
#MedSky
@nature.com
www.nature.com/articles/d41...
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Breast cancer is on the rise: data reveal drastic gap in survival rates
Lack of screening and limited treatment options mean that low- and middle-income countries face higher death rates despite having fewer cases than wealthier nations.
https://www.nature.com/articles/d41586-025-00265-2
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And renal cancer, too! Cancer vaccines this month in Nature
www.nature.com/articles/s41...
🧪
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A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature
A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patie...
https://www.nature.com/articles/s41586-024-08507-5
8 months ago
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And more clinical exploration of cancer vaccines this week in Nature:
www.nature.com/articles/s41...
🧪
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Clonal driver neoantigen loss under EGFR TKI and immune selection pressures - Nature
We show the evolution of a case of EGFR mutant lung cancer treated with a combination of erlotinib, osimertinib, radiotherapy and a personalized neopeptide vaccine targeting somatic mutations, includi...
https://www.nature.com/articles/s41586-025-08586-y
8 months ago
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This week in Nature, important (in more than one sense ) results about mRNA vaccines long term effects in pancreatic cancer:
www.nature.com/articles/s41...
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RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - Nature
In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked lo...
https://www.nature.com/articles/s41586-024-08508-4
8 months ago
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reposted by
Victoria Aranda
Magdalena Skipper
8 months ago
Simply inexplicable! Trump administration to cut billions in medical research funding 🧪
#AcademicSky
www.theguardian.com/us-news/2025...
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Trump administration to cut billions in medical research funding
National Institutes of Health said the $4bn loss will affect ‘indirect’ funding of buildings, equipment and staff
https://www.theguardian.com/us-news/2025/feb/08/trump-administration-medical-research-funding-cuts
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reposted by
Victoria Aranda
Mary Elizabeth Sutherland
8 months ago
Do you ever wonder whether teaching children math in a classroom translates to applied skills? or if those kids that can do applied math would perform well in a classroom setting? A new
@nature.com
paper shows that these skills do not translate 🧪
www.nature.com/articles/s41...
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Children’s arithmetic skills do not transfer between applied and academic mathematics - Nature
Children who learn maths working in markets and children who learn maths only from school were both unable to transfer their skills to new contexts, highlighting a need to reconsider how maths is...
https://www.nature.com/articles/s41586-024-08502-w
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reposted by
Victoria Aranda
Magdalena Skipper
8 months ago
Nearly half the world’s population speaks at least one of the roughly 400 Indo–European languages. Now ancient genomes tell us how it came to pass
@nature.com
🧪
www.nature.com/articles/d41...
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How one language family took over the world: ancient DNA traces its spread
Millennia-old genomes suggest Indo–European tongues originated from the Caucasus mountain region.
https://www.nature.com/articles/d41586-025-00382-y
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reposted by
Victoria Aranda
Francesca Cesari
8 months ago
www.nature.com/articles/d41...
🧪
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Out of Africa: celebrating 100 years of human-origins research
A landmark study reporting the discovery of Australopithecus africanus one century ago put the African continent at the centre of the story of humanity.
https://www.nature.com/articles/d41586-025-00282-1
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reposted by
Victoria Aranda
Christina (Chris) Tobin Kahrstrom
8 months ago
Out now in
@nature.com
: Gut microbiome diversity across African populations - a valuable resource for further research and foundational for global health equity. 🧪
www.nature.com/articles/s41...
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Expanding the human gut microbiome atlas of Africa - Nature
A cross-sectional study from four African countries shows the importance of investigating the gut microbiome in previously under-represented populations and provides a framework for equitable microbio...
https://www.nature.com/articles/s41586-024-08485-8?linkId=12710137
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reposted by
Victoria Aranda
Christina (Chris) Tobin Kahrstrom
8 months ago
Out now in
@nature.com
: Elegant work demonstrating CARD-dependent activation of bacterial gasdermins. 🧪
www.nature.com/articles/s41...
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CARD domains mediate anti-phage defence in bacterial gasdermin systems - Nature
Caspase recruitment domains (CARDs) are present in defence systems that protect bacteria against phage, where the bacterial CARD domain is essential for protease-mediated activation of bacte...
https://www.nature.com/articles/s41586-024-08498-3
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reposted by
Victoria Aranda
Mary Elizabeth Sutherland
8 months ago
How can we stop genetic diversity loss? A meta-analysis in
@nature.com
finds the conservation strategies designed to improve environmental conditions, increase growth rates, and introduce new individuals can maintain or increase genetic diversity🧪https://www.nature.com/articles/s41586-024-08458-x
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Global meta-analysis shows action is needed to halt genetic diversity loss - Nature
A comprehensive meta-analysis of global terrestrial and marine genetic diversity covering more than three decades of research demonstrates rapid loss of genetic diversity and identifies conservation i...
https://www.nature.com/articles/s41586-024-08458-x
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This week in Nature, translational and clinical cardiac stem cell engineering: “Engineered heart muscle allografts for heart repair in primates and humans”
www.nature.com/articles/s41...
🧪
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Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading ...
https://www.nature.com/articles/s41586-024-08463-0
8 months ago
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Victoria Aranda
Sadaf Shadan
8 months ago
Crops face a variety of challenging conditions, including alkaline soil and global warming. @nature, scientists gain molecular insights and apply them to not only make rice both alkali- and temperature-tolerant, but also to further increase its yield.
www.nature.com/articles/s41...
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Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield - Nature
Precise regulation of the phytohormone gibberellin to optimal levels may not only confer alkali–thermal tolerance to Green Revolution rice varieties but may also further enhance their yield, and ...
https://www.nature.com/articles/s41586-024-08486-7
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reposted by
Victoria Aranda
Nature
8 months ago
Analyses of 45,000-year-old bones from Europe allow scientists to pin down when modern humans interbred with Neanderthals, shedding light on the histories of populations with no present-day descendants
https://go.nature.com/4h7FCbA
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Ancient human genomes offer clues about the earliest migrations out of Africa
Oldest Homo sapiens genomes point to dates of mixture with Neanderthals.
https://go.nature.com/4h7FCbA
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reposted by
Victoria Aranda
Magdalena Skipper
8 months ago
To celebrate its 30th anniversary, Nature Medicine launches a new series to spotlight key challenges & opportunities over the next 30 years of biomedical innovation 🎉 🧪
@natureportfolio.bsky.social
www.nature.com/collections/...
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30th Anniversary Series on the Future of Medicine
As Nature Medicine celebrates the 30th anniversary of it’s launch, we reflect on what the future holds for medicine and for our journal.
https://www.nature.com/collections/jcdefebijj
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reposted by
Victoria Aranda
Francesca Cesari
8 months ago
A study in Nature confirms that the phenomenon of mitochondrial transfer can occur bidirectionally between cytotoxic T cells and cancer cells within the tumour microenvironment. This leads to senescence of the T cells and impaired antitumour immunity.
www.nature.com/articles/s41...
🧪
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Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
https://www.nature.com/articles/s41586-024-08439-0
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Victoria Aranda
Nature Portfolio
8 months ago
A study in Nature used deep learning methods to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible antivenom treatments.
https://go.nature.com/4aDxmxK
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Victoria Aranda
Nature
8 months ago
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X
https://go.nature.com/42tH8Ai
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Bluesky’s science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
https://go.nature.com/42tH8Ai
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This week in Nature, how a platform of cardiac organoids can accelerate ASO therapeutic development in DMD: “Rapid and scalable personalized ASO screening in patient-derived organoids” 🧪
www.nature.com/articles/s41...
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Rapid and scalable personalized ASO screening in patient-derived organoids - Nature
A scalable platform for generating patient-specific organoids for testing personalized oligonucleotide therapeutics is described.
https://www.nature.com/articles/s41586-024-08462-1
8 months ago
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More disease modeling technology this week in Nature, through optimization of mitochondrial base editing: “Precise modelling of mitochondrial diseases using optimized mitoBEs” 🧪
www.nature.com/articles/s41...
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Precise modelling of mitochondrial diseases using optimized mitoBEs - Nature
A study reports optimized mitochondrial base editors with reduced off-target effects to facilitate the generation of mouse models of human mitochondrial diseases.
https://www.nature.com/articles/s41586-024-08469-8
8 months ago
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reposted by
Victoria Aranda
Magdalena Skipper
9 months ago
Promising results from a phase I clinical trial of GD2-CAR T cells (immune cells engineered to target the molecule GD2) in children & young adults with diffuse midline gliomas — incurable cancers of the CNS 🧪 A clinical briefing on a new
@nature.com
paper
www.nature.com/articles/d41...
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The road to CAR-T-cell therapy for lethal childhood brain tumours
A phase I trial in young people with a form of glioma tests immune cells engineered to target cancer cells.
https://www.nature.com/articles/d41586-024-04156-w
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reposted by
Victoria Aranda
Magdalena Skipper
9 months ago
Remember Bable Fish from The Hitchhiker’s Guide to the Galaxy? A single model that supports speech-to-speech translation, speech-to-text translation, text-to-speech translation, text-to-text translation & automatic speech recognition is here! 🧪
@nature.com
www.nature.com/articles/s41...
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Joint speech and text machine translation for up to 100 languages - Nature
SEAMLESSM4T is a single machine translation tool that supports speech-to-speech translation, speech-to-text translation, text-to-speech translation, text-to-text translation and automatic speech recog...
https://www.nature.com/articles/s41586-024-08359-z
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reposted by
Victoria Aranda
Magdalena Skipper
9 months ago
Join our news team as a science reporter based in Berlin or Sydney! Applications close January 20th👇🏻 Please help spread the word
@nature.com
@natureportfolio.bsky.social
add a skeleton here at some point
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And lots of cool cancer genomics/genetics this week in Nature too,
www.nature.com/articles/s41...
🧪
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Complex rearrangements fuel ER+ and HER2+ breast tumours - Nature
A study identifies three dominant genomic archetypes of breast cancer induced by discrete mutational processes, describing a continuum of genomic profiles and detailing the mechanisms underlying the p...
https://www.nature.com/articles/s41586-024-08377-x
9 months ago
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Lots of cool AI in Nature this week, including VLM for precision oncology
www.nature.com/articles/s41...
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A vision–language foundation model for precision oncology - Nature
Trained on unlabelled, unpaired image and text data, the Multimodal transformer with Unified maSKed modeling excelled in outcome prediction, image-to-text retrieval and visual question answering, pote...
https://www.nature.com/articles/s41586-024-08378-w
9 months ago
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Victoria Aranda
Flora Graham
9 months ago
The Nature Briefing is back for 2025, and already I'm learning that the Cucuteni–Trypillia culture built giant egalitarian cities in Europe with no temples or palaces and everyone got lots of nice pottery? Then they all disappeared? 🤯
us17.campaign-archive.com?u=2c6057c528...
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Victoria Aranda
Nature Portfolio
9 months ago
Join us for a webinar in which leaders of the Human Tumor Atlas Network will discuss their latest research that was published across Nature Portfolio journals and the work ahead. Register here:
https://go.nature.com/406Dud5
Browse the collection:
https://go.nature.com/41DXk1y
#AcademicSky
🧪
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reposted by
Victoria Aranda
Magdalena Skipper
9 months ago
Fascinating - why do we run as well as we do 3D digital model of the ‘Lucy’ skeleton – a near-complete 3.2-million-year-old A. afarensis - suggests that adaptations in the Achilles tendon & surrounding muscles enable modern humans to run for extended periods 🧪
www.nature.com/articles/d41...
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Humans evolved for distance running – but ancestor ‘Lucy’ didn’t go far or fast
3D models of Australopithecus afarensis suggest the muscular adaptations that made modern humans better runners.
https://www.nature.com/articles/d41586-024-04194-4
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Victoria Aranda
Nature
10 months ago
We've just joined Bluesky 🎉 Follow us for research, news, comment and opinion from Nature journal 🧪
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Today in Nature: “Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours”. A Phase 1/2a trial testing combination of visugromab and nivumab in advanced cancer patients
www.nature.com/articles/s41...
🧪
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Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours - Nature
A study reporting the results of a clinical trial co-administering the GDF-15-blocking antibody visugromab with the anti-PD-1 antibody nivolumab demonstrates that neutralizing GDF-15 can overcome resi...
https://www.nature.com/articles/s41586-024-08305-z
10 months ago
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reposted by
Victoria Aranda
Magdalena Skipper
10 months ago
It’s this time of year again - Nature’s 10 - Ten people who helped shape science in 2024…
@natureportfolio.bsky.social
www.nature.com/immersive/d4...
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Nature’s 10: the people who helped shape science in 2024
A fraud buster, a nuclear-clock maker and a virus hunter. These are just a few of the remarkable people chosen for this year’s Nature’s 10.
https://www.nature.com/immersive/d41586-024-03890-5/index.html
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reposted by
Victoria Aranda
Ulrike Harjes
10 months ago
ICYMI: To celebrate 100+ years of the
#WarburgEffect
, editors from across Springer Nature put together a collection of clinical, translational and preclinical studies as well as commentaries of
#CancerMetabolism
research.
www.nature.com/collections/...
@natureportfolio.bsky.social
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Cancer Metabolism 2.0
The field of cancer metabolism research is entering its 2nd century since the first description of the changes in metabolism of cancer cells by Otto Warburg ...
https://www.nature.com/collections/djjgbfahdf
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reposted by
Victoria Aranda
Mary Elizabeth Sutherland
10 months ago
How do we keep global consumption within what our planet is capable of sustaining? A recent
@natureportfolio.bsky.social
paper finds that focusing on reductions to the food and service sectors could be feasible🧪
www.nature.com/articles/s41...
?
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Keeping the global consumption within the planetary boundaries - Nature
An analysis of the environmental footprints of consumption finds that planetary boundary transgressions can be mitigated by following an effective mitigation pathway focused on the food and services s...
https://www.nature.com/articles/s41586-024-08154-w
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reposted by
Victoria Aranda
Magdalena Skipper
10 months ago
Is COP29 climate deal a historic breakthrough or let-down? A last-minute deal that rescued the COP29 climate talks in Baku, Azerbaijan, is a “fragile consensus”, researchers who study climate finance have told Nature. 🧪
@natureportfolio.bsky.social
www.nature.com/articles/d41...
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Is COP29 climate deal a historic breakthrough or let-down? Researchers react
Rich countries will ‘take the lead’ in finding US$300 billion annually in climate finance to poor countries.
https://www.nature.com/articles/d41586-024-03875-4
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Do reach out if you have any questions about being a Nature editor!
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10 months ago
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reposted by
Victoria Aranda
George Caputa
10 months ago
Sleeping is one of my fav activities. Very excited that we got to share this study by
@mcalpinelab.bsky.social
showing that cardiac inflammation after a heart attack dictates sleep patterns and promotes healing/recovery.
www.nature.com/articles/s41...
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Myocardial infarction augments sleep to limit cardiac inflammation and damage - Nature
Studies in humans and mice show that myocardial infarction recruits monocytes to the brain’s thalamus, promoting sleep, which in turn restricts cardiac inflammation and sympathetic sign...
https://www.nature.com/articles/s41586-024-08100-w
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Blueskying (?) my first paper! This week in Nature, an interesting take on hijacking the developmental pathways of breast involution to target weak links in Triple Negative Breast Cancer:
www.nature.com/articles/s41...
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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution - Nature
AKT inhibitors synergize with agents that suppress the histone methyltransferase EZH2 and promote robust tumour regression in multiple triple-negative breast cancer models in vivo by triggering a...
https://www.nature.com/articles/s41586-024-08031-6
11 months ago
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Victoria Aranda
Mary Elizabeth Sutherland
11 months ago
This month's issue of
@naturehumbehav.bsky.social
covers such an important - and under-discussed and researched - topic. For more, see the collection here:
www.nature.com/collections/...
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Menstruation Matters
Menstruation is part of human life, yet we hide it behind stigma and taboos. In this Focus, our authors discuss why menstruation matters. Tackling significant ...
https://www.nature.com/collections/dfecidfcac
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Victoria Aranda
Henry Gee
11 months ago
go.bsky.app/3WDYs4r
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It’s great to be back to following cool science on social media with my lovely Nature colleagues. Thank you
@endofthepier.bsky.social
for shepherding us to the Nice Place!
11 months ago
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Victoria Aranda
Nature Portfolio
11 months ago
A collection published across Nature Portfolio journals presents early draft maps of cells in the human body from the Human Cell Atlas initiative. The research leverages new data and analytical tools to aid our understanding of human health and disease at a cellular level. 🧪
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The Human Cell Atlas: towards a first draft atlas
In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.
https://go.nature.com/4hW7joE
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