A great reminder that Boston's economic competitiveness begins with "talent density" www.masslive.com/news/2026/06...

AI tools like AlphaFold have transformed the landscape of protein design in less than a decade. Meanwhile, organic chemists are still waiting for their own “AlphaFold moment” for predicting reaction recipes and routes for small-molecule synthesis. cen.acs.org/synthesis/ca... #chemsky 🧪

Sounds promising innovativegenomics.org/news/crispr-...

AI is less immediately threatening in China, but still unpopular because it cuts off the chance for advancement into white collar jobs. Another great article by ChinaTalk open.substack.com/pub/chinatal...

This is the legacy of Pete Hegseth. Scores Fall Ill at Air Force Base After Hegseth Makes Flu Vaccine Optional www.nytimes.com/2026/06/18/u...

VCs expect pitches to come straight from CEOs in a personalized very short note. Anything else suggests a dysfunction.

Bostonians love the Scots even though they are drinking all our beer. #WorldCup

He's created a literal swamp.

This hadn't been high on my radar, but maybe it should be. open.substack.com/pub/larrykot...

More media consolidation 😒

If someone asks what Harvard is doing for the world, show them this list. It's spectacular. news.harvard.edu/gazette/stor...

It sounds crazy, but I guess when somebody tells you their only mistake was a Nazi tattoo, its possible they actually made a series of other mistakes that did not happen to produce a Nazi tattoo.

Last day - thank you

There I was using Claude and all of a sudden it jumped from 4.7 to 4.8! Nice!

If the US had a sensible immigration policy, this Chinese blunder would be a huge opportunity www.bloomberg.com/news/article...

Gift link next 7 days - this moved so fast that the Indian government made X ban the account "as a matter of national security"

Do better Driscoll's! www.al.com/news/2026/05...

"David Sacks, Elon Musk, and Mark Zuckerberg spoke with Trump to derail the AI executive order by warning even a voluntary system for previewing frontier models could become a de facto approval regime" Seems Grok and Meta intend to cut corners on AI safety as they rush to catch up. Shame on them.

Ending of Colbert was really well done youtu.be/zG0HFw0edXY?...

The main thing we are seeing in these GOP primaries is the power of right-wing media to distort reality. Any road to sanity must begin with media reform.

Anthropic acquires NYC-based Stainless, which generates SDKs from APIs, and plans to wind down its hosted products, after reportedly discussing a $300M+ deal (Kirsten Korosec/TechCrunch) Main Link | Techmeme Permalink

"hits hard" is the latest AI driven catchphrase, right up there with "this changes everything"

Quite the chart #Econsky

Read that 32% of NeurIPS papers this session are from USA and 51% are from China.

Funny

The Red Sox coaches leaving town after they were fired en masse. Time will tell if they were the issue or just the scapegoat but either way, I like seeing them here with heads held high.

Clicking a link and hitting a paywall for a publication to which you ALREADY subscribe is not the most annoying thing in the world. But close.

Yvonne Hao calls for optimism, scrappiness, and convergence of tech and bio in Boston (paywall BBJ) www.bizjournals.com/boston/news/...

#Econsky gift link www.bloomberg.com/news/article...

Has there ever been a less difficult decision than Trump or Pope?

The most disappointing rhetorical phrase in Washington these days is "Let me be clear...." followed by some kind of wishful half truth. Please strike both the phrase and the propaganda.

We are nearly one-third done with this calendar year. Moving at warp speed.

The future will look upon touch-tone call trees with the same sick fascination we currently reserve for medical leeches.

The wealthy would do better to give something sane now than to suffer something insane later.

Guessing that what the Dept of Defense was asking Anthropic to do in past was a lot of cyberhacking and that is what led to Mythos. Once Dario saw it work so well, he decided to warn the world about it, rather than secretly put that power in Trump's hands. If so he is a first order hero.

The American president counts Vladimir Putin and Kim Jong-Un as his friends while denouncing the Pope.

Who was the most recent king to be excommunicated by the Pope for moral failings? Hint: he was unfaithful to multiple wives Hint: he became excessively paranoid, anxious, and narcissistic with age -> Did you guess King Henry VIII? Yes that is correct for now. But... stay tuned.

So happy

Lololololol

These are lasting somewhat longer than we expected.

Less two countries and more two realities. In rural areas, an extractive cabal owns the media (Fox, Sinclair, Meta, X, Megachurches) and deliberately creates wedges for political power. The populace is bamboozled. Democracy dies. Any road to sanity must begin with media reform.

When "Gulf Funds back Paramount $81B takeover of Warner" (WSJ) we are watching our domestic news media sold out to biased foreign interests. Democrats should be aggressively blocking and promising to bust up any such deals. The road to sanity starts with media ownership reform.

No war crimes

Christianity is the biggest, most profitable scam in America.

That’s one hell of a cover…..

The rich are smarter to give something rational now than suffer something irrational later. www.theguardian.com/commentisfre...