Dr Spreckley @drmariespreckley.bsky.social leads the AMPLIFY study that seeks to understand how people experience next-generation weight loss therapies, to help identify the types of information and wrap-around support that are most meaningful and needed in real-world care. buff.ly/835YqxD (4/4)

Just 12 studies examined nutrition & diet alongside drug treatment, and as trials varied widely in their approaches to dietary advice and nutritional assessment, lacking standardised protocols and reporting, it was difficult to reach robust conclusions to inform the optimal support. (3/4)

In a systematic review published today, Dr Marie Spreckley, Dr Cara Ruggiero, and Dr Adrian Brown found a lack of robust evidence surrounding nutritional advice and support and its impact on calorie intake, body composition, protein adequacy, and patient experiences. buff.ly/Az65PyP (2/4)

New @cam.ac.uk and @ucl.ac.uk research finds people prescribed weight loss drugs such as semaglutide and tirzepatid may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss. 🧵 (1/4)

Delighted to share that our latest study examining nutritional considerations when using next-generation obesity weight management medications such as Ozempic and Mounjaro is now published in Obesity Reviews. @cararuggiero.bsky.social @adrianbrown.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Dr Marie Spreckley @cam.ac.uk leads the AMPLIFY study, exploring the lived experiences of people using, or who have recently stopped, incretin-based weight loss therapies, to better understand how to support them with information and wrap-around support. Find out more at buff.ly/AxR0QqR (2/2)

"A key strength [of the guidance] is the emphasis on combining medication with behavioural support and on the need for equitable access, rather than presenting drugs as a stand-alone solution." @drmariespreckley.bsky.social comments on new WHO guidance on weight loss drugs. buff.ly/BEypph6 (1/2)

Dr Marie Spreckley is leading the new AMPLIFY study that seeks to understand how people experience next-generation incretin-based therapies, such as semaglutide and tirzepatide, when used for weight management. Read our news post at www.mrc-epid.cam.ac.uk/blog/2025/11... (2/2)

"Nutrition must no longer remain a missing pillar in obesity management medication care." @drmariespreckley.bsky.social @cararuggiero.bsky.social & Adrian Brown on lessons from bariatric interventions on nutritional support needed for GLP-1 receptor agonist assisted weight loss therapy. 🧵(1/2)

Hot off the press 🔥 Amazing work to be a part of led by @drmariespreckley.bsky.social and @adrianbrown.bsky.social. Watch this space! www.nature.com/articles/s41...

I am delighted to share our new perspective piece in the International Journal of Obesity: “Bridging the nutrition guidance gap for GLP-1 receptor agonist therapy assisted weight loss: lessons from bariatric surgery.” www.nature.com/articles/s41... @cararuggiero.bsky.social @adrianbrown.bsky.social

AMPLIFY is a new study led by @drmariespreckley.bsky.social that seeks to understand how people experience next-generation incretin-based therapies, such as semaglutide and tirzepatide, when used for weight management. Read our news post at buff.ly/o6auZ0q 🧵 (1/3)

Fantastic day hosting the @postdocsofcambridge Research Showcase today✨ @cararuggiero.bsky.social

Congratulations to @drmariespreckley.bsky.social for securing her first independent research grant: Amplifying Meaningful Perspectives and Lived experiences of Incretin therapy use From diverse community voices (AMPLIFY) 🎉Thrilled to be collaborating with you on this!

🎭 May Ball 🎭

🎭 May Ball 🎭

The Confidence Interval – from the UN to weight loss research In the latest episode of our podcast series, @drmariespreckley.bsky.social‬ shares her journey to the University of Cambridge, along the way discussing sustainable weight loss and diversity in research. Listen - buff.ly/tEo1tDO

It was a pleasure attending the launch of The Food Foundation’s new report: “Boosting Early Years Nutrition to Support a Healthy Childhood.” Many thanks to @hannahbrins.bsky.social as well as the other organizers and speakers for a great event. I even ran into @drmariespreckley.bsky.social !

Coming soon a new episode of The Confidence Interval podcast. Dr Marie Spreckley from the MRC Epidemiology Unit shares her journey from the UN to the University of Cambridge. Listen to past episodes of our podcast series - buff.ly/npiI4fC

📢 We Are Hiring!! 📢 [Part-time remote working for the University of Cambridge @mrcepid.bsky.social] We are recruiting Intervention Facilitators for a NIHR-funded trial - perfect for health coaches/assistant psychs/student dietitians with an interest in weight management. jobs.cam.ac.uk/job/51082/

We are hiring! We're looking for two post-doc researchers to help us deliver a randomised controlled trial of group model building to address inequalities in diet in English local authorities. Two 3y posts, ideally starting in July. Closing date 4 May. Full details: www.jobs.cam.ac.uk/job/50905/

The 2025 issue 2 of the epigram newsletter is out now Reframing food and rethinking policy Transport and planetary health What is a healthy weight? Featured are @martinwhite33.bsky.social, @jeanmadams.bsky.social, Dr @cararuggiero.bsky.social, & @drmariespreckley.bsky.social buff.ly/PVk8mh2

What an honor! Thank you @mrcepid.bsky.social for the support of this work and my partner in crime, the brilliant @drmariespreckley.bsky.social. I also want to acknowledge our wonderful collaborators @cpft-nhs.bsky.social. #ChildNutrition #FoodInsecurity #FamilySystems #SPROUTStudy

(3/3) Thank you to Sonia Kumar MP and the organisers for hosting this important discussion. @HealthyChildProg #ChildNutrition #FoodInsecurity #Responsive #MRCepid #FamilySystems #SPROUTStudy

(2/3) SPROUT (Supporting Parental Responsive Feeding for Optimal Understanding of Thriving Child Development) is a new study exploring the lived experience of parents and healthcare professionals to support responsive feeding in families experiencing food insecurity.

(1/3) Dr @cararuggiero.bsky.social and @drmariespreckley.bsky.social from the @mrcepid.bsky.social, @uniofcam.bsky.social, presented evidence at Westminster yesterday to inform policy at the Cross-Party Group on a Fit and Healthy Childhood and sharing details of SPROUT.

For International Women’s Day, we celebrate the diversity of voices that drive the transformative power of science. Meet @drmariespreckley.bsky.social, Research Programme Manager, MRC Epidemiology Unit #IWD2025 #AccelerateAction

Another great @ukaso.bsky.social East of England Network Event organised by the brilliant @andreadsmith.bsky.social @cararuggiero.bsky.social & @julia-mueller-phd.bsky.social at @jesuscollegecam.bsky.social 🌟

@mrcepid.bsky.social @cambridgeuni.bsky.social Christmas Party 2024 🥳🥂

📣 New paper 📣 We used a systems thinking approach to map the key actors, structures, incentives, and dynamics that have led to the dominance of UPFs in population diets worldwide. onlinelibrary.wiley.com/doi/10.1111/... #UPFs #ultraprocessedfood #sustainablediets #sustainablefoodsystems

📢 New paper: we developed and validated two novel scales to measure aspects of food insecurity stigma @paulchristiansen.bsky.social bmcpublichealth.biomedcentral.com/articles/10....

Environmental impact and cost to the consumer of meat, milk, and meat and milk alternatives. Much lower impact of all meat and milk alternatives. Unprocessed plant-based options best for both environmental impact and cost. Paper in PNAS by Marco Springmann (link in next post).

Happy to see this paper led by AaronHengist finally published in AJCN on how variable a person's glucose responses can be to duplicate meals even under controlled conditions & implications for precision nutrition. Free access until January 21: authors.elsevier.com/a/1kCIYgSEOABD

Great work @drmariespreckley.bsky.social !

Delighted to see this published in @cellpress.bsky.social review journal Trends in Endocrinology & Metabolism (IF 11.4) 🙂 www.sciencedirect.com/science/arti... @genesandhealth.bsky.social

Great stuff from the Genes & Health team! www.nature.com/articles/s41... @moneeza-ks.bsky.social @sarahfiner.bsky.social @drmariespreckley.bsky.social And many more

GLP-1 agonists are showing promise for alcohol abuse disorder. This is good news, if it holds up in RCTs. Tx for all substance use disorders are badly needed, and the capacity of GLP-1 to modulate generalized craving response may predict benefit for other drugs. jamanetwork.com/journals/jam...

I put together a starter pack of those working in obesity and diet (and related areas) research and policy. I did it quickly this morning, so let me know if you'd like to be added! go.bsky.app/Q3xXqKM

Applications are open for an ESRC-funded PhD focusing on understanding the link between mental wellbeing and T2D self-management, addressing a societal challenge with real-world applications. Closing date: 07/01/2025. For details & applications - https://buff.ly/3BVKroA