"Springer Nature was nevertheless still selling the empty PDF for $39.95 until this story was published" www.science.org/content/arti...

The #OpenSource in the Age of #AI panel will be the second of two panels at #BOSC2026. Find more info, including names and bios of panelists, here: www.open-bio.org/events/bosc-...

The Longitudinal Assessment of protein Function Annotation (LAFA) is live! LAFA compares contributed models to each other and to baselines. If you have a model you would like to upload to LAFA, please let us know! FunctionBench.net

Nethack 5.0 dropped last month. I think I'll take a sabbatical.

Metabullshit 👇

As I'm going to see the Mandalorian & Grogu tonight, here's my take on the rest of the Star Wars franchise: 1977: the best. Han shot first ESB: Excellent. ROTJ: where things started to go bad.

Congratulations to Dr. Parnal Joshi! Onward to your next adventure!

Want to find #prophage in your #bacteria genomes? We built PhiSpy a long time ago, and now we've created a new web page for it: linsalrob.github.io/PhiSpyWeb/ Best of all, the data never leaves your computer! #phage #phagesky

Excited to share: Advances in Protein Function Prediction from the Fifth CAFA Challenge. 📈huge increase in participation, due to @kaggle.com 🤔 New "partial-knowledge" score reveals major open challenges 🗨️ Protein language models are driving progress doi.org/10.64898/202...

Doodle now have an infinity symbol in their logo, to underscore how long it takes to coordinate a meeting.

I forgot that yesterday was World DNA Day. At least I didn't forget my DNA.

When writing the NIH Current & Pending (CPOS Common Form) via SciENcv it omits the "in kind" section when I try to fill it out. Has anyone else experienced this? Is there a way around it?

Have you developed a new #bioinformatics tool to understand #phage or #virus? Make sure you add it to #awesome-virome github.com/shandley/awe...

It does make space flight very relatable, though... www.404media.co/artemis-2-as...

Want to annotate a bacterial genome with structures? @oschwengers.bsky.social bakta and @gbouras13.bsky.social phold got together, and the result is Baktfold: protein annotation across the microbial tree of life using structures www.biorxiv.org/content/10.6... #phagesky #microsky #microbiomesky

חג שמח!

X-post from Bluesky: 🧑‍💻Satellite Hackathon at #ViBioM2026! Join the #Virus #Bioinformatics + @nf_core Hybrid Collaborative #Hackathon & collaborate on bioinformatic tools and ideas & contribute to reproducible workflows & research infrastructure. Want to […] [Original post on genomic.social]

That's relatively new...

Large language models

How Not to be Seen: Predicting Unseen Enzyme Functions using Contrastive Learning https://www.biorxiv.org/content/10.64898/2026.02.23.707489v1

Call for the first 2026 round of the OBF Event Fellowship & overview of the overall round of 2025 www.open-bio.org/2026/03/05/e...

"This phosphodiesterase from E. coli has presented us with a poser. We do not know which node on the EC tree it is on. But we will soon find out." How Not to be Seen: Predicting Unseen Enzyme Functions using Contrastive Learning www.biorxiv.org/content/10.6...

I love curling. curl -X POST -L -H "Content-Type: application/json" -H "Authorization: Bearer <token>" -d '{"key":"value"}' api.example.com/data -o response.json --verbose

The AI of wordle as a grant reviewer: "This proposal isn’t one of the projects I think will be funded based on what I’ve learned from doing science".

New @kaggle.com competition, which I am happy to co-host Can you extract the metadata of mass-spec experiments from scientific papers? Thanks to the NSF National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) for sponsoring. www.kaggle.com/competitions...

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

You made the right choice by opting for Linux and I am proud of you for that. 🥹

We are deeply saddened to share the passing of Amos Bairoch, pioneer of bioinformatics and co-founder of SIB. His lifelong commitment for high-quality, open data transformed global research. We honour his legacy by continuing to build the future of bioinformatics.

My quote of the day For every complex problem there is an answer that is clear, simple, and wrong. H. L. Mencken

Happy There Is A Circulatory System Walking Through The Kitchen Day to all who celebrate.

Academics in Assyria in the 7th c BC complain that admin is preventing them from doing research and teaching

Physicist Lise Meitner died on this day in 1968 just before her 90th birthday, having discovered fission, having been excluded from the Nobel Prize for her own discovery, and having paved the way for women in science anyway. This is her remarkable story: www.themarginalian.org/2016/10/27/l...

🧬The 6th Critical Assessment of protein Function Annotation #CAFA6 #CAFA is growing fast! We now have 295 participants! Join for the love of science🧬machine learning, and 🏆 💵. Please repost. #BIOINFORMATICS #machinelearning www.kaggle.com/competitions...

🧬The 6th Critical Assessment of protein Function Annotation #CAFA6 #CAFA is growing fast! We now have 295 participants! Join for the love of science🧬machine learning, and 🏆 💵. Please repost. #BIOINFORMATICS #machinelearning www.kaggle.com/competitions...

📣 Competition Launch Alert! CAFA 6: Protein Function Prediction hosted by @iastateresearch.bsky.social 🎯 Predict protein function from amino acid sequences 💰 $50,000 Prize Pool ⏰ Entry Deadline: Jan 26, 2026

We just launched the 6th Critical Assessment of protein Function Annotation: CAFA 6 on @kaggle.com CAFA is an ongoing community-driven experiment designed to evaluate computational methods for protein function prediction. www.kaggle.com/competitions...

An open letter about the recent cuts at GigaScience: www.open-bio.org/2025/09/30/2... (open for signatures until the end of October) #OpenScience #OpenData #GigaScience

The Jane Goodall Institute threatened to sue Gary Larson over this cartoon. Goodall told them not to be so stupid, sold it on a tshirt, and wrote the introduction to The Far Side Gallery 5. Absolute legend.

Unannotated translation products are widespread in model E. coli www.biorxiv.org/content/10.1...

This may be the most important paper ever published about NIH funded research. www.science.org/doi/10.1126/...

Obviously not a biochemist.

Welcome @isvm-society.bsky.social to bsky, the International Society for the Viruses of Microorganisms. Check the new look website isvm.org and become a member for free! #phagesky #microsky

Huge opportunity, Josie is amazing

The @scilifelab.se ancient DNA unit is looking for an bioinformatician placed at Uppsala University. This is a great way to be part of diverse #aDNA research projects as a staff scientist with permanent (!!) employment: www.uu.se/en/about-uu/...

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

Slightly diminish a band: Manganese Maiden

I think this should act as a cautionary tale for anyone thinking of using ChatGPT for anything even remotely important. They probably asked “PhD level” ChatGPT 5 to create this joke of a graph, and, predictably, it failed in a miserable and misleading way.

"I asked the AI" is not research. clauswilke.substack.com/p/i-asked-th...

Happy RNA Day to those who celebrate! 🧪 It’s AUG 1: the day we Met 🤓

I was today years old when I learned there is an Uncle Fester protein. Lol. www.uniprot.org/uniprotkb/F5...