🧵1/ We’ve just published a new paper in Science Advances looking at why influenza can become so dangerous during pregnancy. A lot of people think this is simply because pregnancy suppresses the immune system. Our data suggest the story is more complicated than that.

Our new paper in Science Advances shows that TLR7, a viral RNA sensor, reshapes the maternal immune response to influenza in pregnancy, amplifying vascular inflammation and adverse maternal and foetal outcomes. @oxibgroup.bsky.social #pregnancy #influenza #TLR7 www.science.org/doi/10.1126/...

TLR7 signaling drives systemic maternal and fetal pathology during gestational influenza infection www.science.org/doi/10.1126/... @stellaliong.bsky.social