Very proud of our new review article on the Beta 1-Adrenergic GPCR now available on bioRxiv: www.biorxiv.org/content/10.1.... With @saureli.bsky.social @valeriorizzi.bsky.social and Nicola we used OneOPES to fully converge the free energy landscapes associated with B1AR apo/holo activation.

Told my relatives over Christmas that these are the "protein models" I work with.

Our latest @acspublications.bsky.social JCIM study unveils new insights into pre-miR21 conformational dynamics using innovative computational techniques. Potential game-changer for RNA processing inhibition. #MicroRNA #ComputationalChemistry #DrugDiscovery pubs.acs.org/doi/10.1021/...

📢 New #preprint describing our community effort to share #plumed tutorials arxiv.org/abs/2412.03595 ! Explore the tutorials at www.plumed-tutorials.org