Frederik Post
@freddyomics.bsky.social
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Deep Visual Proteomics in the Mann Lab, Copenhagen
My first PhD paper on the spatial characterization of colon organoids is finally out! Thanks to
@hausmannannika.bsky.social
for spearheading this collaboration with me. Read more about the study in the post by
@mannlab.bsky.social
.
add a skeleton here at some point
20 days ago
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reposted by
Frederik Post
Annika Hausmann
21 days ago
Very happy to share that part of my postdoc work
@ucph.bsky.social
@kimbakjensen.bsky.social
lab is out now in
@cp-cellsystems.bsky.social
! In close collaboration with
@freddyomics.bsky.social
@mannlab.bsky.social
we show that orthotopically transplanted organoids recapitulate in vivo phenotypes 👇🏼
add a skeleton here at some point
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reposted by
Frederik Post
Mann Lab
6 months ago
Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution. Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time.
www.nature.com/articles/s41...
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Deep Visual Proteomics maps proteotoxicity in a genetic liver disease - Nature
High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing e...
https://www.nature.com/articles/s41586-025-08885-4
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reposted by
Frederik Post
Mann Lab
7 months ago
Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood.
nature.com/articles/s41588-025-02089-2
#PediatricProteomics
#pQTL
First author
@liliniu.bsky.social
explains ⬇️
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Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics
This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.
https://nature.com/articles/s41588-025-02089-2
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