New year, new projects — and often new tools to evaluate. If you’re curious about CryoCloud, there are two simple ways to get started: 🔷 Free academic account 🔷 30-day evaluation trial Links in the comments 👇 #cryoEM #structuralbiology

As 2025 comes to an end, thank you to the CryoCloud community. Every conversation, dataset, and piece of feedback helps us build a better platform for structural biology. From all of us at CryoCloud, wishing you a warm, restful holiday season and a great start to 2026. ✨

CryoCloud Map of the Month (Holiday Edition 🎄): Alpha‑Synuclein Fibril For December’s edition, we reprocessed EMPIAR‑12229 and generated a 2.3 Å map of the in vitro alpha-synuclein fibril using CryoCloud. 🔬 Dataset size: 5,193 movies 🧠 Compute time: 56.5 hours #CryoEM

📢 CryoCloud Newsletter: End-of-Year Edition is out! A huge thank you to our users, collaborators, and the structural biology community for being part of the journey this year 💙 👉 Read it here: connect.cryocloud.io/newsletter-d... #CryoCloud #CryoEM #StructuralBiology #DrugDiscovery

🌟 Employee Spotlight: Boy Persoon As Co-Founder and CPO of #CryoCloud, Boy has been the driving force behind turning our ambitious product vision into a functional, user-first platform. If you’ve ever used our platform and thought “this just works” – Boy probably had something to do with it 🍀

🚀 CryoCloud v2.18 is live! This release includes two new beta features designed to further automate #cryoEM workflows, along with other improvements. What’s new: 🔹 AutoClass2D – automatically select 2D classes using a reference .mrc file 🔹 Workflow Export & Import lnkd.in/eb8ic_TK #CryoCloud

🚨 New blog: GPU-accelerated motion correction Motion correction remains one of the slowest and most costly steps in #cryoEM workflows. So we rebuilt it from scratch. Our new in-house GPU-accelerated CryoCloud Motion Correction is designed for speed, scale and high throughput. lnkd.in/eiJgsYgJ

🔥 Three years ago, the CryoCloud platform went live 🎉 Today, scientists from 25+ countries rely on it every day for analysing their structural biology data – and we couldn’t be prouder of how far things have come. Thank you to all our users, collaborators, and early supporters 💙 #CryoEM

🚀 CryoCloud v2.17 is live! This release introduces Targets – a new way to organise datasets & projects around your molecule of interest. Targets make it easier to browse results, store reference files in one place and launch automated workflows. connect.cryocloud.io/release-note... #CryoEM

November Map of the Month: CDK-activating kinase (CAK), an oncology target bound to the covalent inhibitor THZ1 💊 We reprocessed EMPIAR‑11793 and produced a 2.5 Å map of the ~85 kDa CAK-THZ1 complex using CryoCloud. 🔬 Dataset size: 12,572 movies 🧠 Total compute time: 52 hours #CryoEM #CryoCloud

🚀 CryoCloud v2.16 is live! This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows. Full release notes → connect.cryocloud.io/release-note... #CryoEM #StructuralBiology

🌟 Employee Spotlight: Anna Boronina Anna brings a strong mix of ML and software engineering to #CryoCloud. She’s behind our ML-based particle picker, which has expanded since its initial release to include contamination segmentation, models for diverse targets & lightning-fast performance. #cryoEM

Back from a #PSDI2025 in Basel. Lots of good discussions and clear interest in practical ways to handle growing cryo-EM and X-ray data volumes. We shared results from our large-scale automated analysis of 53 EMPIAR datasets (key takeaways in the comment below!) #CryoEM #StructuralBiology

We’re heading to #PSDI2025! Meet the CryoCloud team and don’t miss our talks: ⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis 🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud Drop by our booth or book a chat 👇 connect.cryocloud.io/meetings/cry... #CryoEM #XrayCrystallography

October Map of the Month: GLP-1R With pharma racing to develop next-generation obesity and diabetes drugs, this #GPCR needs no introduction 💊 We reprocessed EMPIAR-10673, showing GLP-1R bound to its natural ligand GLP-1, and achieved a 2.7 Å map on CryoCloud using 40 h of compute. #CryoEM

🌟 Employee Spotlight: Tadej Satler (@tadejsatler.bsky.social) Tadej brings deep scientific and computational expertise to CryoCloud. His recent work on GPU-accelerated motion correction (MotionCorr CC) is a key step toward faster, more accessible cryo-EM. Proud to have him on the team! 🚀 #CryoEM

🚀 CryoCloud version 2.13 is here! Highlights: 🔹 Adjust map visualisation with new, easily-accessible iso-level slider ⬇️ 🔹 Create particle subsets using metadata values 🔹 Clearer dataset-import feedback 🔹 Custom browser tab names, and more Full notes: connect.cryocloud.io/release-note... #CryoEM

🚀 CryoCloud v2.12 is here! This release brings major project grid usability updates, including filtering by processing branch, so you can highlight an entire job tree and focus on one processing path at a time (preview below!) Full release notes: connect.cryocloud.io/release-note... #CryoEM

⏰ Tomorrow! Join us for the CryoCloud #XRayCrystallography webinar featuring a short introduction to the new pipeline and a panel discussion on today’s challenges and opportunities in high-throughput XRC data processing. events.teams.microsoft.com/event/6f09a4... #CryoCloud #StructuralBiology

🚀 CryoCloud MotionCorr – our new GPU-accelerated motion correction is here! Released last week as part of CryoCloud v2.11, our new GPU-accelerated motion correction algorithm delivers up to 4× faster performance than the legacy CPU-based Relion implementation. v2.11 notes: t.co/zK4YKotSWI #CryoEM

🚀 CryoCloud v2.11 is here! Version 2.11 brings up to 4x faster motion correction, contamination detection in CryoCloud Picker (see a preview below!), and major performance boosts across the platform. Full release notes: connect.cryocloud.io/release-note... #CryoEM #CryoCloud

⏳ 1 Week to Go! After introducing CryoCloud’s integration of Global Phasing’s Pipedream workflow, we’ll be joined by four experts to discuss the challenges and opportunities in high-throughput #XrayCrystallography. Register here: events.teams.microsoft.com/event/6f09a4...

CryoCloud is heading to Women in Electron Microscopy #WeM2025 this week! We’re proud to sponsor this inaugural event supporting women in electron microscopy. Our own @ievadr.bsky.social will speak on cloud-native automation to enable high-throughput #cryoEM for drug discovery. See you there!

📢 CryoCloud Newsletter – Issue #2 is here! 💎 New X-ray Crystallography pipeline 🧬 Biologics case studies: antibodies & vaccines 🚀 Platform release notes 🎤 CryoCloud at WeM 2025 👋 Team update: Welcome, Josh! 📅 Upcoming events & more Read it here: connect.cryocloud.io/newsletter-o... #cryoEM #XRC

🚀 CryoCloud Platform Release 2.10.1 is here! This is a big one – CryoCloud now supports X-ray Crystallography alongside #cryoEM 💎 📖 Read the full release notes, including other improvements and bug fixes: connect.cryocloud.io/release-note... #CryoCloud #XrayCrystallography #StructuralBiology

🚀 New in CryoCloud: Automated X-ray Crystallography Data Processing! Join our launch webinar on Oct 16 (11 AM ET | 5 PM CET) featuring a CDK2 case study + industry panel on high-throughput XRC. 👉 Register: lnkd.in/ev4e7K_h #StructuralBiology #XRayCrystallography #XRC #CryoEM

📣 Live from the Dutch Structural Biology Meeting in Delft! Robert (@riborob.bsky.social) is presenting our CryoCloud poster on accelerating #cryoEM workflows. We’re also sponsoring the Poster Prize 🧦🎉 Big thanks to Arjen Jakobi (@cryotud.bsky.social) for organising. Excited for today’s discussions!

September Map of the Month: Small Data, Big Insights ⚡️ From just 233 movies, CryoCloud delivered a 3.2 Å SARS-CoV-2 spike map in 3.5 h. Fast and efficient #cryoEM, exactly what vaccine design teams need when screening dozens of antigen variants per day. 📬 DM or [email protected] for more info!

Thrilled to welcome Dr Joshua White as Senior Application Scientist at CryoCloud! With deep expertise in single-particle analysis & end-to-end #cryoEM workflows, Josh will lead data analysis, user training & support. Excited to have his experience & energy on board! 🚀 @jbrwhite.bsky.social

The CryoCloud team just returned from a retreat in the Belgian Ardennes 🌿 For the first time, all 11 of us met in person, with colleagues from 6 countries. We had work sessions, walks, meals, spotted deer 🦌 … and launched our first edition of CryoCloud #cryoEM socks! 🚀

🌟 Employee Spotlight: Ilja Gubins ‪(@igubins.bsky.social‬) 🚀 From building CryoCloud’s multi-cloud infrastructure from scratch to leading ISO certification & security efforts, Ilja has been the driving force of our technical foundation. 🙌 We're proud to have him as our Co-Founder & CTO! #CryoEM

Tomorrow’s the day! 🚀 Join our webinar "CryoCloud: Secure & Automated Cryo-EM Data Processing in the Cloud" to learn how CryoCloud helps streamline #cryoEM workflows with automation, scalability, and cloud-native tools. Register here: events.teams.microsoft.com/event/85b6a4... #structuralbiology

August Map of the Month: Epitope Mapping edition! We reprocessed EMD-19016 and got a 2.7 Å map of PDCoV RBD in complex with two neutralising Fabs ✨ 📊 4,736 movies ⚡️ 35.5 h cloud compute 🔬 2.7 Å map from 120k particles (0.3 Å better than published) 📬 DM or [email protected] for more info! #CryoEM

📢 CryoCloud Newsletter – Issue #1 is LIVE! We’ve just launched our very first newsletter – sharing product updates, science highlights, upcoming events, team news, and more. 📰 You can read it here: connect.cryocloud.io/newsletter-a... #cryoEM #structuralbiology

🔐 Cloud Security FAQ – Part 3: ISO & Private Cloud In our final post of this series, we are covering two of the most frequent questions we get from customers: What IT certifications do we have? And can we have a private cloud setup? ☁️ 👉🏻 Click through to learn more about these topics! #cryoEM

Two weeks to go! ⏳ Join us on August 26 to see CryoCloud in action – automated, scalable, and built for cryo-EM data processing in the cloud. Register today and join the conversation 👇 #cryoEM #structuralbiology #CryoCloud #cloudcomputing

🌟 Welcome to the team, Kirill Sidelev 🇺🇦! With 12 years in software development, Kirill is focusing on the end-to-end user experience – turning complex #cryoEM workflows into intuitive, reliable tools, so scientists spend less time on software and more time making discoveries. 🚀 #NewHire #CryoCloud

🔐 Cloud Security Part 2 In this second post of our security FAQ series, we are digging into what happens behind the scenes to keep your data safe every single day. ➡️ Click through to learn more about how we manage access, monitor activity, and keep your data safe. #CloudSecurity #CryoEM

🔐 Cloud Security Part 1 We often get asked about cloud security – and rightly so. In this three-part series, we’re addressing the most common questions we hear from customers. ➡️ Click through to find out how we protect your data with end-to-end encryption and built-in redundancy. #Cloud #CryoEM

📢 Webinar announcement! CryoCloud: Secure & Automated Cryo-EM Data Processing in the Cloud Join to get a tour of the app and learn about real-world case studies of challenging targets 🔬 📅 August 26 🕓 4:00 PM CEST / 10:00 AM EDT 👉 Register here: events.teams.microsoft.com/event/85b6a4... #cryoEM

🌟 Employee Spotlight: Oleg Mikhailovskii Oleg is a Computational Structural Biologist with expertise in biophysics, MD, and data science. At CryoCloud, he designs algorithms for #cryoEM & #XRC, building high‑throughput methods that boost speed and scalability in the cloud 🚀 @oleg-phd.bsky.social

🚀 Kicking off our new Map of the Month series with MrgD‑Gi! We reprocessed EMPIAR‑11074 and got 3.1 Å from an automated workflow and 2.9 Å after polishing ✨ Interested in CryoCloud? 📧 Reach out at [email protected] 📅 Or book a meeting here: meetings-eu1.hubspot.com/ieva-drulyte... #CryoEM #GPCR

3rd year running the #UtrechtMarathon 🏃‍♀️ This year feels extra special since I now work right here on Utrecht Science Park, where the race starts and finishes! ⏱️ Back to the 10k this year (49:18) Well done to my @cryocloudio.bsky.social teammates @riborob.bsky.social & Thijmen on the half marathon!

CryoCloud is heading to #Novalix2025 in Strasbourg! Come meet us at the booth to talk #cryoEM, structural biology, and how our cloud platform speeds up data processing & storage. #DrugDiscovery #StructuralBiology #CryoCloud

We are excited to be attending the #ccpem symposium in Nottingham this week! Come to our booth to: 🖥️ get a live demo and learn more about CryoCloud‘s latest features 🍫 grab some chocolates 🧬 enter our raffle to win your 3D printed protein structure of choice #biotech #cloud #cryoEM

Welcome to the team Ieva 🎉🎉 We are excited to have you onboard!