Lori Koch
@lbkoch9.bsky.social
📤 51
📥 80
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Scientist. Avid book clubber. Overly enthusiastic dancer.
reposted by
Lori Koch
Andrea Musacchio
10 months ago
www.biorxiv.org/content/10.1...
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Molecular requirements for PLK1 activation by T-loop phosphorylation
Activation of PLK1, a master mitotic kinase, requires phosphorylation of its activation segment on Thr210, within a basic consensus sequence for Aurora kinases. Aurora B-dependent phosphorylation of T...
https://www.biorxiv.org/content/10.1101/2025.07.25.666769v1
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Awesome!!
#kinetochoresforever
add a skeleton here at some point
12 months ago
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reposted by
Lori Koch
Hannah Long
about 1 year ago
With many thanks to our keynote speakers - Emily Wong
@em6wong.bsky.social
, Manuel Irimia
@mirimiam.bsky.social
, Sean Munro, Sarah Teichmann, Wolfgang Baumeister and Christine Cucinotta
@chrstne.bsky.social
- what a fantastic couple of days of cross-cutting science, and a lively discussion session!
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reposted by
Lori Koch
Adele Marston
over 1 year ago
@lbkoch9.bsky.social
and I wrote a Current Opinion piece highlighting recent progress in our understanding of centromere and kinetochore function in meiosis.
www.sciencedirect.com/science/arti...
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The functional organisation of the centromere and kinetochore during meiosis
Meiosis generates gametes through a specialised cell cycle that reduces the genome by half. Homologous chromosomes are segregated in meiosis I and sis…
https://www.sciencedirect.com/science/article/pii/S0955067425000249
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