Alex Lercher
@alercher.bsky.social
📤 581
📥 889
📝 22
Immunologist | HFSP Postdoctoral Fellow @RiceLaboratory | PhD @bergthalerlab | opinions are my own.
pinned post!
How do past viral infections influence future viral diseases? We found that SARS-CoV-2 recovery protected from severe influenza A virus disease. But how come? There seemed to be some antigen-independent immunological memory going on.. Paper at Immunity:
www.sciencedirect.com/science/arti...
12 months ago
1
16
2
Thank you very much
#ASciNA
and
@fwf-at.bsky.social
for the ASciNA Young Investigator Award! Link to publication
@cp-immunity.bsky.social
:
www.cell.com/immunity/abs...
add a skeleton here at some point
25 days ago
2
5
1
reposted by
Alex Lercher
Stephanie Flores
29 days ago
Innate immune memory is wild 🧠 Alexander Lercher from Rockefeller dives into how cells remember past infections and prep for future ones. Type I interferon doing way more than just fighting viruses! Full interview:
buff.ly/5TKEJ9o
#CytokineSociety
#ImmuneMemory
#TypeIInterferon
#CellsHaveMemoriesToo
loading . . .
Member Highlight: Alexander Lercher on Innate Immune Memory and Real-World Microbe Responses - Biweekly newsletter of the International Cytokine & Interferon Society
My name is Alexander Lercher, and I am currently a Postdoc in the lab of Charlie Rice at Rockefeller University in New York, and I am particularly excited about studying immune responses in the context...
https://signals.cytokinesociety.org/2025/09/28/member-highlight-alexander-lercher/
0
6
3
Thank you for the member highlight
@cytokinesociety.bsky.social
and see you all in Seattle for Cytokines 2025!
signals.cytokinesociety.org/2025/09/28/m...
loading . . .
Member Highlight: Alexander Lercher on Innate Immune Memory and Real-World Microbe Responses - Biweekly newsletter of the International Cytokine & Interferon Society
My name is Alexander Lercher, and I am currently a Postdoc in the lab of Charlie Rice at Rockefeller University in New York, and I am particularly excited about studying immune responses in the context of real-world microbe exposure. Out from the lab, my biggest hobby for the past years has been to explore the
https://signals.cytokinesociety.org/2025/09/28/member-highlight-alexander-lercher/
about 1 month ago
0
2
0
Extremely happy to be awarded the Sidney & Joan Pestka Post-graduate award! Thank you
@cytokinesociety.bsky.social
and all my mentors, colleagues and collaborators throughout my career so far!
add a skeleton here at some point
4 months ago
1
11
1
Location, infection history, antigen persistence shape the phenotype of tissue-resident T cells (Trm), challenging the idea of a universal framework for Trm identity across organs and diseases. High/low antigen immunogenicity may add another layer...
@cp-immunity.bsky.social
tinyurl.com/49dkc3j7
11 months ago
0
6
1
A commensal bacterium triggers systemic antibody responses via skin lymphoid structures and can be engineered as a topical vaccine – great therapeutic potential! Two studies in
@nature.com.web.brid.gy
by the Fischbach and Belkaid labs
tinyurl.com/5yahn47t
tinyurl.com/4n4btxap
11 months ago
1
16
4
Great Spotlight by
@virusesimmunity.bsky.social
and
#SashaTabachnikova
on our recent publication in
#Immunity
, where we studied antiviral innate immune memory in alveolar macrophages in the context of respiratory viral infections!
www.cell.com/trends/immun...
loading . . .
SARS-CoV-2 reprograms murine alveolar macrophages to dampen flu
Innate immune cells that are epigenetically reprogrammed by infection can modify host responses to subsequent infections. Lercher et al. have identified epigenetic reprogramming of murine airway-resid...
https://www.cell.com/trends/immunology/fulltext/S1471-4906%2824%2900273-4
12 months ago
1
15
5
If you are rather an auditory person than a reading person – TWIV discussed our recent paper on antiviral innate immune memory in sequential respiratory viral infections. Paper review starts at 37:00, more general discussion and broader implications at 1:10:00.
open.spotify.com/episode/777w...
loading . . .
TWiV 1165: What doesn't kill us primes our macrophages
This Week in Virology · Episode
https://open.spotify.com/episode/777wxTXydhZkTWDYAhHPEj?si=646e93589cb74216
12 months ago
0
10
3
How do past viral infections influence future viral diseases? We found that SARS-CoV-2 recovery protected from severe influenza A virus disease. But how come? There seemed to be some antigen-independent immunological memory going on.. Paper at Immunity:
www.sciencedirect.com/science/arti...
12 months ago
1
16
2
Chronic autoimmunity rewires metabolism in progenitors, correlating with innate immune memory formation in macrophages that increases antibacterial activity but might also aggravate autoimmune diseases?
shorturl.at/SZ1Ww
#CellStemCell
12 months ago
0
10
4
Curious how commonly circulating respiratory viruses affect respective disease? Past SARS2 infection ameliorates disease caused by secondary influenza virus via innate immune memory in airway-resident macrophages.
@biorxivpreprint.bsky.social
link below.
www.biorxiv.org/content/10.1...
almost 2 years ago
1
5
3
you reached the end!!
feeds!
log in
