Terry R Suk (@terryrsuk.bsky.social)

We’re happy to share that our labs first #ALS and #FTD study “A stress-dependent TDP-43 SUMOylation program preserves neuronal function” is now online at Molecular Neurodegeneration! doi.org/10.1186/s130...

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A stress-dependent TDP-43 SUMOylation program preserves neuronal function - Molecular Neurodegeneration Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are overwhelmingly linked to TDP-43 dysfunction. Mutations in TDP-43 are rare, indicating that the progressive accumulation of exo... https://doi.org/10.1186/s13024-025-00826-z