Thanks @daniellebeckman.bsky.social for sharing our recent work of DISCO-seq 🤗

🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...

Wow, @erturklab.bsky.social team did it again! Bringing science fiction to the real world 👋👋

Such a great study, combining tissue clearing, imaging and scRNA-Seq 👏🏼

"Conventional techniques restrict molecular profiling to pre-selected 2D sections, losing systemic context and introducing anatomical bias by sampling less than 0.001% of a whole organism. To overcome these challenges, we developed DISCO-seq" www.biorxiv.org/content/10.6...

Thrilled to share our work on DISCO-seq, which combines RNA-preserving tissue clearing with whole-organ 3D imaging to enable anatomically unbiased single-cell transcriptomics, with applications in cancer and infection biology. #SpatialBiology #DISCOseq Preprint link www.biorxiv.org/content/10.6...

As of today, the main finding of my PhD is published in the European Journal for Neuroscience! 🥳🥳 Together with Gesine Müller, we looked at hemispheric asymmetries in the mouse auditory cortex. We find layer, sex, and hemispheric differences: doi.org/10.1111/ejn.... 🧵

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - @erturklab.bsky.social @hendrikdietz.bsky.social go.nature.com/4gNLjeC

Congrats to the whole community in the @erturklab.bsky.social including first author @jie-luo-lab.bsky.social starting his new Lab at Purdue just last week! Nice work y'all! Amazing contribution to this growing body of work using LightSheet microscopy for whole mouse imaging. 🧪🧵🔬

Our SCP-Nano paper is online now in Nature Biotechnology 🎉👏 Kudos to all the authors, collaborators and reviewers for bringing this important piece of work! #LNP #mRNA #nanotechnology #AAV #AI #imaging #nanocarrier

Amazing experience to share the stage with spatial biology experts @European Society of Spatial Biology (ESSB) and present our work of 3D spatial-Omics to an audience of 550 plus from 26 countries 🤩 Kudos to the founding members of @SpatialBio for putting together such a fantastic event 🎉👏 #3D #Omic

Let’s celebrate together the dawn of spatial proteomics- not just in 2D but in a groundbreaking 3D fashion, thanks to our pioneering work of DISCO-MS 🎉

Check out our latest preprint-MouseMapper- charting the intact organism at cellular resolution #obesity #AI #inflammation #neurodegeneration #proteomics

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...