Department of Chemistry | University of Zurich
@chem.uzh.ch
๐ค 76
๐ฅ 61
๐ 58
Active ingredient from the bug: Oliver Zerbe from
@chem.uzh.ch
is working on an active ingredient that attacks disease-causing bacteria in a new way and kills them. Read more:
acrobat.adobe.com/id/urn:aaid:...
17 days ago
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Dynamic reconstruction of CoSeโ active sites revealed! Why this catalyst excels in both acidic and alkaline HER/OER environments. Read more about:
www.nature.com/articles/s41...
19 days ago
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Congratulation to Nina Hartrampf on receiving the Werner Prize 2026 awarded by the Swiss Chemical Society. ๐๐๐
about 1 month ago
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In this work, we present fully ab initio simulations of Fe L-edge X-ray absorption spectroscopy (XAS) for archetype single-molecule magnet tetrairon Fe4 using a linear-response TDDFT with spinโorbit coupling.
pubs.acs.org/doi/10.1021/...
about 1 month ago
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Congratulation to Momir Malis from the Luber Group on winning a SNSF Spark Grant (Spark Grants are for rapid funding of novel and unconventional ideas) for his project: Improving the variational density functional theory for excited electronic states with machine learning ๐
about 1 month ago
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Congratulation to the three winners of a Semesterpreis of the
@chem.uzh.ch
: Anita Lopes Souto (Group Fenner), Matteo Lisibach (Group Sigel), Timo Nicolas Stern (Group Helbing).
about 2 months ago
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This work offers a detailed vibrational reference for [MoโSโ]โดโบ and [MoโSโโ]ยฒโป, establishing Raman and IR spectroscopy as robust techniques for characterising MoโS molecular clusters in both fundamental and applied research:
doi.org/10.1088/2515...
about 2 months ago
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In this paper (
doi.org/10.1007/s113...
) a simple, straight-forward protocol for the determination of radiotracer distribution in excised tissue samples based on weighed standards of the injected formulation included in the activity measurement is presented.
about 2 months ago
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This paper (
doi.org/10.1016/j.jo...
) highlights the pivotal role of charge carrier-selective interface engineering in broadening the scope of available semiconductor materials for photo(electro)catalytic oxidation reactions, irrespective of the doping type of the light-absorbing material.
about 2 months ago
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This study
pubs.acs.org/doi/10.1021/...
experimentally demonstrates the manifestation of strong electronic correlations in the geometric and electronic structures of a single molecule.
2 months ago
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Our results (
doi.org/10.1063/5.02...
) reveal that surface charges significantly alter ionic conductivity and determine the direction of the electro-osmotic flow and of the diffusio-osmotic current, thereby advancing the understanding of transport at the nanoscale.
@chem.uzh.ch
3 months ago
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The
@locbp.bsky.social
@chem.uzh.ch
developed a gene expression reporter system based on the coexpression of the protein of interest BiP/GRP78 and the reporter HaloTag.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
3 months ago
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Congratulation to Lukas, former PhD student of the Spingler group
@chem.uzh.ch
๐๐๐
3 months ago
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The synergistic effect achieved by combining PDT, PTT and photocages with traditional treatment modalities represents a significant advancement in cancer treatment. New findings presented in ChemComm (
pubs.rsc.org/en/content/a...
) by Flavia Kradolfer et al.
@chem.uzh.ch
.
3 months ago
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The
@chem.uzh.ch
was the first university in Europe to admit women and the first in the world to award a doctorate in chemistry to a woman, Lydia Sesemann from Viborg. The Swiss Academy of Sciences is now honoring the UZH as an important historical site for chemistry.
www.chem.uzh.ch/en/admin/eve...
3 months ago
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Congratulations to all the Best Oral Presentation Awardees
@chem.uzh.ch
at the SCS Fall Meeting: Anton Kliuchynskyi ๐, Katarzyna Hanc ๐, Marc Fernรกndez ๐, and Sandro Fischer ๐
4 months ago
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Congratulations to all the Poster Presentation Awardees
@chem.uzh.ch
at the SCS Fall Meeting: Noah Rychener ๐, Vincent Freiburghaus ๐, Henriette Lรคmmermann ๐, Fan Liu ๐, Nanchen Dongfang ๐ and Shangkun Li ๐
4 months ago
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Wow! Bogdan Dereka
@chem.uzh.ch
receives an ERC starting grant. Congratulation to Bogdan on this huge success.๐๐๐
4 months ago
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Congratulation to Fabrizio Creazzo from the Luber group
@chem.uzh.ch
on winning the Holcim Stiftung Grant๐๐๐.
4 months ago
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Sandra Luber and her co-workers
@chem.uzh.ch
demonstrate that CP2K provides a unique and powerful toolkit for studying a wide range of excited-state phenomena in complex molecular and extended (periodic) systems.
pubs.acs.org/doi/10.1021/...
4 months ago
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The results of the
@locbp.bsky.social
and co-workers
@chem.uzh.ch
establish the hemicyanine chemical family as a promising scaffold for paraptosis research and suggest potential as a therapeutic lead for diseases where traditional apoptosis pathways are dysregulated.
pubs.acs.org/doi/10.1021/...
4 months ago
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Prof. Dr. Sarah Reismann is the Givaudan-Karrer Lecturer 2025. For more information:
www.chem.uzh.ch/en/admin/eve...
5 months ago
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reposted by
Department of Chemistry | University of Zurich
Michal Jurรญฤek
6 months ago
#ChemCup2025
Highlights โฝ๐ 6th Edition ofย ChemCup Biggest so farย withย 14 teamsย andย 180+ participants Soccer, volleyballย & ultimate splash Watch FULL video on YouTube:
youtu.be/JTCq3H00Fio?...
๐ฅย Filmed & edited byย Matรบลก Okajฤek
#ReadyToReact
@chem-uzh-ch.bsky.social
@chemsky.bsky.social
#ChemSky
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2-{FeโNiโOโ} is introduced as a new molecular platform for in-depth studies of NiFe synergisms, along with ligand engineering or polymer matrix strategies. New Paper published by the Patzke group
@chem-uzh-ch.bsky.social
and the Mougel group at ETHZ.
pubs.acs.org/doi/10.1021/...
6 months ago
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reposted by
Department of Chemistry | University of Zurich
Patrick Cieslik
8 months ago
Happy to share that my second paper from the
@hollandlab.bsky.social
is online now! We have discovered a new bioconjugation strategy and have tested it in terms of Radioimmunotherapy with Tb-161! Thanks to all authors!
doi.org/10.1021/jacs...
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Light-Induced Synthesis and Radiotheranostic Treatment of Gastric Cancer with 161Tb-Labeled Monoclonal Antibodies
Radiolabeled monoclonal antibodies (mAbs) form a major branch of nuclear medicine and are used in the development of tracers for both diagnostic imaging and molecularly targeted radio(immuno)therapy (RIT). Since treatment options for many types of late-stage cancers are limited and these diseases become refractory to classic chemotherapy, new tools are required to improve patient outcomes. The high tumor uptake and specificity of mAbs, coupled with increased therapeutic range of energetic ฮฒโ-emitting radionuclides, offers a potential solution to overcome traditional problems associated with poor tissue penetration of antibody-drug conjugates, chemotherapeutic resistance, and off-target accumulation, which can lead to adverse responses. The challenge is to develop efficient and reliable chemical methods that provide simultaneous selectivity and high stabilization of the radiometal via complexation chemistry, with rapid access to new bioconjugate bonds on protein that avoid the loss of bioactivity. Here, we designed a new octadentate bispidine-chelating system, functionalized with a light-responsive tetrazole unit, and demonstrated the chemoselective derivatization of sulfhydryl groups introduced on the protein surface. High radiolabeling and bioconjugation yields of 161Tb-onartuzumabโan engineered mAb fragment targeting the human hepatocyte growth-factor receptor (c-MET; a characteristic biomarker found in clinical samples of several diseases, including gastric adenocarcinomas)โwere obtained under ambient conditions after 5 min of light-induced coupling. Comprehensive biochemical and animal experiments including cellular binding assays, noninvasive ฮณ-ray imaging, biodistribution studies, and pharmacokinetic measurements established the viability of using 161Tb-onartuzumab to target c-MET expression in vivo. Subsequent RIT studies in MKN-45 xenograft models demonstrated that the 161Tb-onartuzumab radiotracer formed by photoradiosynthesis permitted low-dose therapy studies that led to efficient targeting and treatment of tumor models. Collectively, the new complexation and chemoselective photoconjugation chemistries overcome some of the limitations in traditional labeling approaches. Photoradiosynthesis represents an excellent platform for building future antibody-based radiotracers for applications in diagnostic and therapeutic medicine.
https://doi.org/10.1021/jacsau.5c00219
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Photoradiosynthesis represents an excellent platform for building future antibody-based radiotracers for applications in diagnostic and therapeutic medicine. Published by
@hollandlab.bsky.social
, โฌ
@chem-uzh-ch.bsky.social
together with Nick van der Meulen at PSI:
pubs.acs.org/doi/10.1021/...
6 months ago
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Congratulation to the two successful candidates of the
@chem-uzh-ch.bsky.social
on receiving an UZH Postdoc Grant ๐๐
6 months ago
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Congratulation to all successful candidates of the
@chem-uzh-ch.bsky.social
on receiving an UZH Candoc Grant ๐๐๐๐๐
6 months ago
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This study
tiny.cc/jw0o001
highlights the significance of operando spectroscopy methods for revealing transformations of metal carbodiimides under electrochemical conditions, which will facilitate their efficient applications in electrochemical syntheses of small molecules.
@chem-uzh-ch.bsky.social
6 months ago
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New Paper about Vibrational Excitations in Magnetic Triangular Nanographenes from the Juricek Lab
@juriceklab.bsky.social
@chem-uzh-ch.bsky.social
in collaboration with the Nanotech-Lab at EMPA:
pubs.acs.org/doi/10.1021/...
6 months ago
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Congratulation to Raoul Herzog from the Hamm Group
@chem-uzh-ch.bsky.social
on winning a poster prize at the 22nd International Conference on Time-Resolved Vibrational Spectroscopy
6 months ago
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Kathrin Fenner
@chem-uzh-ch.bsky.social
already signed the Stockholm Declaration on Chemistry for the Future: read and sign:
www.stockholm-declaration.org
6 months ago
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Congratulation to Sandra Luber on receiving the very prestigious 2024 Walter Thiel Award as first woman and first person from Switzerland.
@chem-uzh-ch.bsky.social
๐๐๐
7 months ago
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New insight for understanding the efficiency loss mechanisms at the semiconductorโelectrolyte interface and for interpreting the interfacial behavior of photovoltaic systems and photocatalysts in
@jacs.acspublications.org
by the Patzke Group
@chem-uzh-ch.bsky.social
โฌ
pubs.acs.org/doi/full/10....
7 months ago
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Congratulations to all the winners of this semester's CMSZH teaching assistant award. You did all an excellent job in teaching. ๐ ๐๐ to Florian, Marc, Noah, Vรฉronique, Abdul, Balint and Delia
7 months ago
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ChemCup on July 2nd
@chem-uzh-ch.bsky.social
๐๐ โฝ๐
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7 months ago
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Check out the new series on polymers by chemistry unwrapped
@chem-uzh-ch.bsky.social
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7 months ago
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Congratulations to all runners of the ChemUnited team
@chem-uzh-ch.bsky.social
who ran at the 50th SOLA. ๐๐๐
8 months ago
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Congratulation to Kaifeng Wang from the Zelder Group
@chem-uzh-ch.bsky.social
โฌ on winning a prize for the best poster at the SCS Spring Meeting 2025. ๐๐๐
8 months ago
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Congratulation to Anita Lopes on winning a Semester prize UZH for her Master Thesis ๐๐๐
8 months ago
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The new paper published by the Holland group demonstrated that photoradiosynthesis can be employed to develop a variety of rhenium based radioimmunoconjugates for future applications in tumor targeted radioimmunotherapy.
pubs.rsc.org/en/content/a...
9 months ago
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Congratulation to Kasimir, Anton and Sergio, the winners of the CMSZH Travel Award 2025 ๐๐๐
9 months ago
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The American Peptide Society is pleased to announce thatย Dr.ย Nina Hartrampf, from the Department of Chemistry at the University of Zรผrich,ย has been selected to receive theย 2025ย Early Career Lectureship.ย This Lectureshipย recognizes scientific excellence at the beginning of oneโs independent career.
9 months ago
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reposted by
Department of Chemistry | University of Zurich
Michal Jurรญฤek
9 months ago
Big thank you to all tutors who helped train young talents for the Swiss Chemistry Olympiad during the preparatory weekend at the Department of Chemistry, University of Zurich โค๏ธ๐๐๐
@juriceklab.bsky.social
#ChemSky
#PiSky
#Outreach
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New paper out by Cesare Berton and Jason Holland
@chem-uzh-ch.bsky.social
featured on the cover of ChemComm
pubs.rsc.org/en/Content/A...
9 months ago
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New video: chemistry unwrapped: CHIRALITY
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9 months ago
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ChemCup is coming soon. Prepare yourself - looking forward to meeting you all ๐
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9 months ago
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Congratulation to Nina
@chem-uzh-ch.bsky.social
๐๐
9 months ago
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chemistry.unwrapped @uzhchemistry.bsky.social
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10 months ago
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This study from the Tilley Lab @uzhchemistry.bsky.social highlights the significance of morphology control in optimizing SbโSeโ photocathodes, providing insights for future material and device design.
pubs.rsc.org/en/content/a...
10 months ago
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