@almudenachaves.bsky.social
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reposted by
Leading Edge Fellows Program
8 months ago
Congratulations
@almudenachaves.bsky.social
!!!
add a skeleton here at some point
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Also honored to see our work highlighted in Nature! Huge thanks to Navdeep S. Chandel and Ram P. Chakrabarty for the thoughtful and insightful News & Views piece, describing the unexpected role of Ogdh and alpha-ketoglutarate in intestinal healing.
www.nature.com/articles/d41...
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Mitochondrial molecule has unexpected role in tissue healing
A key component of the TCA cycle, a series of reactions that occurs in energy-generating organelles called mitochondria, can dictate the fate of intestinal stem cells.
https://www.nature.com/articles/d41586-025-01583-1
8 months ago
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Thrilled to share that the last paper of my postdoc is now out in
@nature.com
! We show how metabolic rewiring through OGDH drives tissue regeneration and stem cell fate. A wild and rewarding ride—huge thanks to Scott Millman and the Scott Lowe lab!
www.nature.com/articles/s41...
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Metabolic adaptations direct cell fate during tissue regeneration - Nature
Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment and offering...
https://www.nature.com/articles/s41586-025-09097-6
8 months ago
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reposted by
Leading Edge Fellows Program
9 months ago
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines. Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
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