Adrien Tassou
@adrtas.bsky.social
📤 25
📥 35
📝 5
Pain neuroscientist
Big news! My K99 application has been awarded 🥳🎉 I'm excited to work together with
@zenbrainest.bsky.social
and @MarkZylka to explore how distinct peripheral neuron types shape pain representation in the brain.
6 months ago
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🌟 Excited to share our new review published in RAPM ! 🌟 Happy to have worked with Cyril Rivat and Philippe Richebé on this piece of work in which we explore the mechanisms underlying chronic post-surgical pain.
rapm.bmj.com/content/50/2...
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Mechanisms of chronic postsurgical pain
Chronic pain after surgery, also known as chronic postsurgical pain (CPSP), is recognized as a significant public health issue with serious medical and economic consequences. Current research on CPSP ...
https://rapm.bmj.com/content/50/2/77
about 1 year ago
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reposted by
Adrien Tassou
Robert Gereau
about 1 year ago
A big day for pain care, and for pain science.
www.fda.gov/news-events/...
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FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain
The FDA approved Journavx (suzetrigine) 50 mg oral tablets, a first-in-class non-opioid analgesic to treat moderate to severe acute pain in adults.
https://www.fda.gov/news-events/press-announcements/fda-approves-novel-non-opioid-treatment-moderate-severe-acute-pain
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reposted by
Adrien Tassou
Matan Geron
about 1 year ago
I am glad to share our recent work, now published in Cell! A
@zenbrainest.bsky.social
and Scherrer lab collaboration developing and validating a new peripherally restricted DREADD system! Great team work with Hye Jin Kang, Brian Krumm,
@adrtas.bsky.social
, and others
www.cell.com/cell/abstrac...
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Structure-guided design of a peripherally restricted chemogenetic system
Kang et al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system.
https://www.cell.com/cell/abstract/S0092-8674(24)01275-3
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