Time to try something new.

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

Professors please pull up a chair. I’ve been talking to my classes about what has been going on. I explained indirect costs to them. I talked to them about what a probationary employee is in the government. At the end of class they asked if we could talk about it more. (1/)

We’re #hiring a Director for Studio D3, our center for data-driven discovery at the @alleninstitute.bsky.social. 🧪 www.linkedin.com/jobs/view/41...

Mental health treatments should be guided by science, not misinformation. With 13% of American adults relying on SSRIs to manage depression and anxiety, the new HHS Secretary’s unscientific claims about these medications are cause for outrage 🧪 www.motherjones.com/politics/202...

Oh. My. God. grants.nih.gov/grants/guide...

Seeing a lot of hype about AI models trained for “under $50.” Let’s be real—these models are distilled from much larger models trained with massive resources. Distillation is useful, but calling it “cheap training” seems misleading. What am I missing? www.theverge.com/news/607341/...

Aptly put: Tom Frieden, a former CDC director, compared the halting of outbreak updates to “finding out that your local fire department has been told not to sound any fire alarms”. www.ft.com/content/6067...

When the Trump administration took a key climate justice tool offline, a coalition of data scientist heroes restored it within 48 hours. 🧪 www.ehn.org/scientists-r...

What AI should exist — but doesn’t yet — to transform biology? The Paul G. Allen Frontiers Group has launched the Ask Anything, Change Everything campaign to gather bold ideas on how AI can revolutionize our understanding of fundamental biology. alleninstitute.org/ask-anything...

Aviary from FutureHouse provides a new framework for training language agents on real-world scientific challenges, including protein stability, DNA engineering, and literature-based question answering. 🧪 arxiv.org/pdf/2412.21154

Merry Christmas (to those who celebrate) Photo credit: Grok

Inside me are two wolves: one wants to make cinnamon rolls from scratch and the other doesn't want to go to the grocery store Okay they're not wolves more like sloths

The Allen Institute and the University of Washington have released a new AI search tool to answer scientific queries of OpenAccess content Preprint released in @arxiv-cs-cl.bsky.social OpenScholar: Synthesizing Scientific Literature with Retrieval-augmented LMs arxiv.org/abs/2411.14199

Meet ACE - a new tool for comparing annotations across Allen Institute transcriptomic taxonomies! Join us for a webinar on how to use it in your #neuroscience research, incl. studies using our Alzheimer's datasets. 📆 Dec. 18, 9:30am PT 💻 Webinar 🎟️ alleninstitute.org/events/cell_... #neuroskyence

alleninstitute.org/careers/inte... Internships and Postbac opportunities open at the Allen Institute, applications close January 7th 2025. Great opportunity for anyone interested in life sciences research or science-support careers. Spread the word!

Cool Yule read: this article highlights how behavioral diversity in artificial intelligence “teams” can significantly enhance problem-solving & adaptability, something that could change how we approach challenges in (AI) research. 🧪 arxiv.org/abs/2412.16244

Whoa: 9 sea snake species have regained the genetic requirements for advanced color vision, showing that complex traits lost to evolution can be regained. phys.org/news/2024-12...

I’m so stealing this idea. Such a cool way to ensure #deib is built into a team’s mindset. Thanks for sharing, @sarahstern.bsky.social

The Washington Post nails it: AI is transforming healthcare, from diagnostics to personalized treatments. 2025 will be the year of AI in life sciences—thoughtful integration is critical. 🧪 Read more: www.washingtonpost.com/opinions/202...

🧪Abhishaike Mahajan examines Recursion’s shift from cell painting to brightfield microscopy. The piece highlights how #ml has unlocked brightfield imaging as a label-free alternative, addressing challenges of cell painting. A must-read: www.owlposting.com/p/why-recurs...

I used to spend about half my time thinking about ways we can better understand how to use AI in #biology — but increasingly, I’m worried about how about how we scale platforms to cope with data volumes 🧪🧵

Predicting the results of experiments is challenging, especially in fields like neuroscience. This recent study shows that fine-tuned LLMs, like BrainGPT, can predict neuroscience results more accurately than human experts on benchmarks. 🧪 https://www.nature.com/articles/s41562-024-02046-9.pdf

@jshendure.bsky.social and team continually blow me away

Moravec’s Paradox is such a fascinating concept: today’s AI can tackle complex tasks like reasoning or drug discovery—things that push human limits. But it still struggles with what humans find simple, like picking up a coffee cup. Biology & AI remind us how differently intelligence can evolve. 🧪

This is a great fellowship for any postdoc who wants to work with #neuro data in a nurturing environment at @alleninstitute.bsky.social. Deadline is approaching!

This is the best take on the potential of predictive biology I’ve come across 🧪 open.substack.com/pub/creode/p...

Tom suggests replacing the logic of prereg -> confirmation with the logic of train/validation/test splits. The place this approach is really, really needed is in historical data — where we can never get another equivalent sample! Our ordinary understanding of replication is broken there.

I ran nearly 8,900 of my tweets through ChatGPT to analyze patterns in my digital footprint. It revealed insights into my political affiliation, career history, and personal life. Here’s what I learned. 🧵🤖

I like this article, despite its clickbaity title — largely because there’s stuff for us to do as regular scientists 🧪 www.nature.com/articles/d41...

Framing AI as a threat to human agency oversimplifies its role and potential. We need to focus on how AI can complement human decision-making — especially in fields like life sciences, where it’s accelerating discoveries 🧪 www.journals.uchicago.edu/doi/10.1086/...

This idea is still good

Pew’s latest report on public trust in scientists is a must-read: Public Trust in Scientists and Views on Their Role in Policymaking. Trust is strong, but transparency and inclusivity are key to keeping it. 🧪🧵 www.pewresearch.org/science/2024...

Been away for a few days; big storm knocked out power and Internet at home. Won’t be restored til Sunday. Sigh…

I’m finding myself thinking more and more about how we can continue to advance state of the art in science despite a funding climate that is likely to change 🧪🧵 www.instagram.com/p/DCUUYoBuiS...

The first known use of singular “they” is so old that not only does it pre-date singular “you,” it wasn’t even spelled with a “th” When William and the Werewolf, in 1375 CE, used singular “they,” it was spelled with a Thorn

This is cool: Boltz-1 by the MIT Jameel Clinic supports biomolecular interaction modeling, offering an open-source tool that matches the accuracy of leading proprietary models 🧪

Work (or play) with multimodal data from thousands of cells across three species using the Cell Type Knowledge Explorer from @alleninstitute.bsky.social knowledge.brain-map.org/celltypes 🧪

Dan Goodwin and @homeworld.bsky.social get it — fabulous and wide-ranging conversation with George Church

Froyo good. (Science still good, if you are wondering…)

This would be much more fun to read if the stakes weren’t so high techcrunch.com/2024/11/15/o...

No surprise: AI in genome studies is running into problems like biases and false positives, often due to incomplete or unbalanced datasets. So, what can be done? 🧪🧵 www.the-scientist.com/ai-assisted-...

spot on: “If we can’t simulate the whole dynamic process in a computer, we have to experiment with it in reality. This is Amdahl’s Law: a process is only as fast as its slowest required step. To break through, we need to solve fundamental wet lab bottlenecks, not just improve code.” bit.ly/3CGMb5t 🧪

Having flashbacks to the Biden debates

What I’m reading: RNA-GPT aligns RNA sequences with natural language for better research insights. Wonder if it can generalize well across diverse RNA types and tasks? 🧪 arxiv.org/abs/2411.08900

I wouldn’t be surprised if this post was written by an AI agent dreaming of one day ”going rogue” metr.org/blog/2024-11...

My best received thread was me responding to @scrippsocean.bsky.social who profoundly posted “science good”. It is indeed good.

This is hard to hear. A lot more cuts to Federal science funding are likely in the offing. We need to find new/better/more ways to drive interdisciplinary collaboration and cooperation in science 🧪

Science needs Englebart’s notion of IA (intelligence augmentation) as opposed to McCarthy’s AI — don’t tell me an answer, help me find answers that I wouldn’t have thought of myself 🧪

#TeamScience is one of our core tenets at @alleninstitute.bsky.social, but sometimes it’s hard for humans to break through prejudices/pride related to disciplines. Important to remember that **no one is “science adjacent”** (not finance, admin, or any other role)