Last respiratory virus season 278 children in the US died of influenza, more than any year since 2009. The majority were previously healthy, but 90% had *not* received a flu vaccine. Facts are stubborn things www.nytimes.com/2025/09/04/h...

"Once trusted experts are removed and advisory bodies are stacked, the results are predetermined. That isn’t reform. It is sabotage." Susan Monarez WSJ op-ed www.wsj.com/opinion/robe...

NIH whistleblowers say HHS manipulated the grant review process to undermine vaccines. @nytimes.com www.nytimes.com/2025/09/04/h...

Me with my recent writing

Circling back to this paper in CMGH from earlier this year on the generation & functionality of human intestinal organoids Very timely read for #GIsky as the NIH & FDA are prioritizing new approach methodologies (NAMs) like this www.cmghjournal.org/article/S235...

Incredibly upsetting and infuriating Our biomedical enterprise is being absolutely tanked by this administration

Important info for researchers and grant writers: New statement from the NIH Director discussing the priorities of the agency - these are unsurprising considering the news from the past few months www.nih.gov/about-nih/ni...

Did I miss a major NIH announcement? I was working on an R01 for a NOSI and just got word it will expire early Sept 2025 when the original expiration date was Sept 2027. I just checked funding opportunities and it looks like most (if not all) active NOSIs are set to expire this fall?

New article in Research Professional News [Sorry about the paywall] www.researchprofessionalnews.com/rr-news-usa-... 1/6

RFK Jr. Vowed to Find the Environmental Causes of Autism. Then He Shut Down Research Trying to Do Just That. Story by @fastlerner.bsky.social www.propublica.org/article/rfk-...

This year the ASH Bridge Grant is funding 25 scientists with $3.75M, 5X more than last year, to keep hematology research moving forward. Congratulations to the recipients! https://bit.ly/3HJ51Ma #HemeSky #MedSKy #ASHAwards

I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...

During acute pancreatitis, the body produces its own protective molecule - lactate💪 An unlikely protector, lactate encourages anti-inflammatory activity to facilitate pancreatic repair🛡️ 🧪 www.cmghjournal.org/article/S235...

How to recognize shoddy studies that claim to link vaccines and autism. Essay by @unbiasedscipod.bsky.social Gift link: nyti.ms/3UUNrIp

“Kennedy would be less hazardous if he decided to do cardiac surgery. Then he would kill people only one at a time,” writes former CDC Director William Foege. www.statnews.com/2025/08/18/r...

By @rickabright.bsky.social, former Director of BARDA... 🛟medsky 🧪 health policy sociology polisky idsky 😷

Dear #LiverSky #HepatoSky researchers: PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025 Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out! pscpartners.org/research/res...

❓Shifts in cell metabolism drive liver cancer - but what are the mechanisms? 🎯This study found that a pathway (hexosamine biosynthetic pathway) may play a role in liver cancer progression www.cmghjournal.org/article/S235...

Today, Bhattacharya sent a document entitled "NIH Priorities and Internal Review of Intramural and Extramural Programs" to Institute and Center Directors and other leaders. I am trying to get a clean copy. These "Priorities" will likely be "Agency Priorities" for grant funding and termination.

Please sign and share our petition to remove RFK Jr. www.change.org/p/rfk-jr-mus...

🚨23% of ulcerative colitis patients w/ total abdominal colectomy w/ ileal pouch-anal anastomosis have pouch failure ❓Why? 🎯Post-procedure chronic inflammation & immune cell activity may be risk factors @aga-cmgh.bsky.social #GIsky www.sciencedirect.com/science/arti...

"NOFOs will no longer be included in the weekly NIH Guide Table of Contents subscription emails. You can use Grants.gov subscription services to receive notifications of new NIH funding opportunities." 🧪 grants.nih.gov/grants/guide...

New RFPs from AGA: $40k over 1 yr for an ECI (with a CDA, e.g., NIH K) studying the pathogenesis, prevention, diagnosis, or treatment of digestive cancer gastro.org/research-and...

“The AI in the study probably prompted doctors to become over-reliant on its recommendations, ‘leading to clinicians becoming less motivated, less focused, and less responsible when making cognitive decisions without AI assistance,’ the scientists said in the paper.”

I obtained an early copy of the government's new food pyramid

RFK has announced that he is developing a vaccine against all viruses. Yes, every single one. The whole, uh, "phylum"

#GIsky Pfizer and the AGA are offering a new grant opportunity that will support IBD research Areas of interest: 🌎Real-world data to model IBD 🧬S1P receptor modulators 🖥️Novel methods of diagnosis & monitoring philanthropynewsdigest.org/rfps/rfp1813...

NIH Director Jay Bhattacharya claims that he wants science to be open to all ideas. Today’s executive order requires a Trump political appointee to review and decide which research projects should be funded. They are desperate to kill science.

Transcellular, interorgan, & host-microbial communication - oh my! Read more about these communication styles in metabolic homeostasis in a new @aga-cmgh.bsky.social special collection 👇Read online here www.cmghjournal.org/article/S235...

I had my physical on Friday. My doctor told me I was up to date on all my vaccinations, but there was a recommen-- "I'll take it. Whatever you've got before they take them all away."

BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.   How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?  Trump must end this illegal funding freeze.

Senators push to protect NIH funding, rejecting Trump’s plan to cut funding by 40% An encouraging move, but there is still lots of uncertainty www.nature.com/articles/d41...

Big NIH news: Starting in FY 2026, allowable publication costs will be capped in an effort to make more science open and accessible What is the cap? TBA. This is a critical step to see if any significant changes will be made and what publisher reactions will be. www.nih.gov/news-events/...

#LiverSky #HepatoSky Bile acids (BAs) rise after high fat diet (HFD) to aid in fat digestion, but this may fuel gastroesophageal cancer (GEAC) However, controlling BA levels by boosting FXR activity (receptor that regulates BAs) can reverse GEAC features www.cmghjournal.org/article/S235...

📖Editors Essential Reading In primary sclerosing cholangitis (PSC), some ductal cells grow (proliferate) while others die off (senescence) Why? The MYC protein acts like a switch to decide the fate of these cells 🧪#LiverSky read below www.cmghjournal.org/article/S235... @aga-cmgh.bsky.social

The NIH is dismissing dozens of vetted scientific reviewers to install politically-aligned replacements This compromises US research by invoking a political takeover of the funding process - ensuring MAGA/MAHA loyalists fill these spots to push their biased agenda www.nature.com/articles/d41...

1. We interrupt this programming for some LEGITIMATELY GOOD NEWS Violent crime in Baltimore has PLUMMETED to historic lows How did the city do it? Baltimore adopted a comprehensive set of "woke" policies, treating violence as a public health issue

The NIH is dismissing dozens of vetted scientific reviewers to install politically-aligned replacements This compromises US research by invoking a political takeover of the funding process - ensuring MAGA/MAHA loyalists fill these spots to push their biased agenda www.nature.com/articles/d41...

Update on funding curves and late non-competitive renewals. First, funding curves for new and competitive renewals. 1/n

I’m trying to figure out how #COVID and #LongCovid can affect women's periods (by disrupting brain circuitry involving the hypothalamus) for a big project. Do you or anyone you know have had disruptive changes in the menstrual cycles after getting COVID or any of the symptoms below?

Big NIH news: Starting in FY 2026, allowable publication costs will be capped in an effort to make more science open and accessible What is the cap? TBA. This is a critical step to see if any significant changes will be made and what publisher reactions will be. www.nih.gov/news-events/...

🧪The U.S. is becoming a #ScienceDesert. Our loss will be their gain. www.cbsnews.com/news/france-...

Senate committee on appropriations markup meeting is starting now. They'll be discussing a lot of stuff, but in particular, science agencies like NSF & NASA. Yesterday Sen. Moran indicated funding would be 33.9 billion, preserving FY '24 numbers. www.appropriations.senate.gov/hearings/ful...

RIGHT NOW: The full Senate appropriations committee is meeting today (now!) to deliberate on yesterday's subcommittee recommendations. New detail: Cuts for NSF going from... 56% (President's request) --> 0.67% (Senate subcommittee proposal, NOT 67%) Long road still ahead, but HOPE!!

FDA and NIH further promote their initiative to replace animal testing with non-animal models NIH announced that they will no longer fund proposals that rely exclusively on animal testing www.drugdiscoverytrends.com/nih-announce...

I did this before in German but I guess today is a good day to compile English resources on why AI isn‘t actually intelligent and also a real danger: 🧵

🆕Study on the role of Piezo1 in IBD ⬆️In IBD, Piezo1 is increased in intestinal macrophages and promotes inflammation 🧬Piezo1 signals through NLRP3/NFkB 🎯Blocking Piezo1 protects mice from IBD-like damage 🔗 www.cmghjournal.org/article/S235...