5-years in the making this paper has been a real journey! Also, a fun collaboration with @frimanscience.bsky.social @jofoth.bsky.social Edze Westra, Simon Lovell, Aras Kadioglu #mevosky #phagesky

Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/... Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺

#phagesky www.cell.com/trends/micro...

New phage therapy publication!🦠 #phagesky We analysed an MRSA phage therapy case study, assessing how predictions made in vitro differed when using one (standard practice) or multiple bacteria isolates from the patient. Collaborative work: Exeter and Queen Astrid hospital doi.org/10.1093/jamb...

New Consensus Statement in Nature Microbiology! Working with low-biomass microbiome samples? From deep subsurface rocks to human lungs, contamination is a major challenge. We offer field-to-data analysis guidelines to help keep your results clean. 📖 doi.org/10.1038/s415...

Whoa, F-pilus dependent phage MS2 whips off it's capsid before entry into the cell?? www.sciencedirect.com/science/arti... "Extracellular uncoating of bacteriophage MS2" #phagesky

We have been working on ways to find #phage with long shelf-life and this one is a winner. 12 months freeze-thawing as much as you like, no loss of viability #phageSky #microSky rdcu.be/ewnzT

#phagesky www.biorxiv.org/content/10.1...

#phage #phagesky

#phage #phagesky www.biorxiv.org/content/10.1...

💊 Antibiotics damage the gut barrier via impaired mucus production independently of the microbiota. A consideration for those using antibiotic induced depletion of the microbiome in mice https://www.science.org/doi/10.1126/sciadv.adp4119

We're advertising a fully funded PhD to explore the PK-PD of Phage therapy being developed for the treatment of Cystic Fibrosis lung infections. The post is in the Department of Pharmacology and Therapuetics at the University of Liverpool. @livuni-ismib.bsky.social @jofoth.bsky.social

Phage DisCo can be further multiplexed with three bacterial strains in co-culture, and, when tested with characterized phages, the fluorescent signal shined! Maybe you can see where the disco ball comparison comes in here. 🪩 4/

a triangle 🔺 it’s a basic shape, but no bacteria is a triangle a clothes hanger, a slice of pizza, a dorito—all triangles just not bacteria

Please sign up, it will be fun! Open for all with an interest in AMR and genomics (in the UK and elsewhere). www.targetamr.org.uk (and please give @target-amr.bsky.social a follow!)