Modern proteins are built from a set of 20 amino acids, but “early Earth” likely had only about 10 of them. Using AI-based protein design tools, researchers show it is possible to build stable, well-folded proteins from just this simpler set.

New research shows that stress biases the hippocampus toward spotting patterns rather than storing detailed memories. This shift helps the brain anticipate what’s coming next, but at the cost of recalling precise details.

Researchers report the first evidence that immune cells from the blood and skull can enter the brain without a clear blood-brain barrier leak while remaining molecularly distinct from microglia. This hints at gentler brain immune therapies compared to irradiation or heavy chemo.

The 3 best-performing peer reviewers on ResearchHub in Q3 2025.

30 days until SciCon 2025. ResearchHub’s 4th annual conference bringing top scientists, founders, and funders together for a full day of discussion and open networking.

A new preprint shows that a common enzyme can “unzip” polyurethane foams (used in furniture and insulation) into its original components to remake fresh foam. If this scales, it points to true closed-loop foam recycling, less landfill, and less need for new petrochemicals.

A new preprint establishes the theoretical foundation for photonic extreme learning machines that compute by propagating light through diffusive media.

What are the highest-potential areas of research that are underfunded today? We asked AI to imagine the answers discussed by researchers on ResearchHub.

Intermittent fasting leads to changes in metabolism, immunity, epigenetics, and the microbiome. This preprint followed 114 women for 6 months, providing molecular evidence behind this popular practice. Iron balance and immune remodeling are key to its health benefits.

$5000 Bioinformatics and Genomics Proposal Spotlight 📅 Sept 25| 🕒 1 PM PDT | 📍 LinkedIn Live You’ll hear 3-min pitches, ask questions, and help decide who gets the $5K grant.

$5000 Bioinformatics and Genomics Proposal Spotlight 📅 Sept 25| 🕒 1 PM PDT | 📍 LinkedIn Live You’ll hear 3-min pitches, ask questions, and help decide who gets the $5K grant.

Our 4th annual conference, SciCon, takes place on December 4, 2025 with the leading minds in science and tech. 🎥 It’s invite-only, with limited seats. But the conversations matter to everyone, so recordings will be shared publicly. Speaker lineup coming soon.

We’ve paid out over $890,000 to peer reviewers. • 10-day avg. turnaround • 9010 reviews completed We’re celebrating #PeerReviewWeek by rethinking incentives in peer review. On ResearchHub, peer review is fast, open, and paid.

The Coinbase listing of ResearchCoin (RSC) makes it far more accessible to everyday users and paves the way to onboard the next wave of scientists into the ResearchHub ecosystem.

Purdue PhD student Grigorii Rudakov explains why progress in biomedical research is often slow.

Basic science creates the biggest breakthroughs. Yet it’s the most underfunded type of research. Researchers from the Wolfram Institute seek funding to explore how DeSci DAOs can realign incentives for better funding and avoid the traps of traditional models. 🧵 1/8

Milestone: Over $1 million in research funding deployed on ResearchHub.

Here’s how our new Funder Referral Program works: 1️⃣ Share your unique link. 2️⃣ Funder backs a proposal. 3️⃣ You both get 10% funding credits for more research.

New record on ResearchHub: Nearly 300 peer reviews completed in the past 7 days, our highest week ever. Key stats: ⏱ Avg. peer review time: 10 days 💰 $880,770 paid to reviewers to date A huge thank you to our editorial team and every reviewer helping to push science forward.

$250,000 in research funding has just been secured to investigate whether energy healing can change brain activity related to chronic pain. Supported by DMT Quest and the ResearchHub community. 1/11

When searching for $150 peer review bounties, filter ResearchHub’s Earn tab by your areas of expertise to find the right opportunities for you.

On ResearchHub, you can earn $150 per peer review.

Post a bounty. Solve your research problem.

A new fMRI study on Wim Hof breathing has reached its funding goal on ResearchHub. It’s the first human trial to test how this breathwork technique might boost brain waste clearance and mental health. 🧵 1/5

Peer-review and peer-fund pilot projects on @researchhubf.bsky.social! I just funded: NeuroSC: Leveraging Pretrained Single-Cell Models for Brain Cell Classification on ResearchHub. www.researchhub.com/fund/4262/ne...

Why peer review your paper on ResearchHub? → Faster, open process (10 days avg.) → Detailed, constructive feedback → More eyes on your paper → Reviewers get paid Request a free peer review for your paper 👇 airtable.com/apptLQP8XMy...

Discover how decentralized science (DeSci) is changing the game for researchers. 👇 www.linkedin.com/pulse/what-d...

New on ResearchHub: Share content with one click.

Turns out that I had some research tokens on @researchhubf.bsky.social -- earned from my past publications(!!) -- that I could use to fund new research proposals submitted by others. I just did exactly that. Why have you not? Be the change you want to see. www.researchhub.com/fund/4261/ef...

Why fund science through ResearchHub?

This $33,000 study could change how psychedelics are made. Instead of synthesizing and testing blindly, it uses quantum chemistry + AI to predict which compounds are safe before they're made. 1/7

A $644 nano-grant might not sound like much. But it could pave the way for new peptide-based therapies targeting drug-resistant Tuberculosis, still responsible for over 1.3 million deaths each year. 🧵 1/6

Most people think innovation comes from working harder. This new study (from our collaboration with @cos.io‬) indicates otherwise. Innovation starts with setting the right goals. 🧵 x.com/ResearchHub... 1/8

"How does the process of explaining affect one’s beliefs?", a Research Plan submitted to Lifecycle Journal, is now under review with @researchhubf.bsky.social. Go check it out if you'd like to be part of the evaluation process! www.researchhub.com/paper/943858...

The 3 best-performing peer reviewers on ResearchHub in the last 3 months.

Effective July 1, 2025, all NIH-funded research must be publicly available upon publication. No more 12-month delay. The Public Access Policy, originally set for Dec 31, 2025, was moved up by 6 months. If taxpayers fund it, they have access from Day 1. x.com/NIH/status/...

A popular psychology treatment may not be as effective as we thought. A reanalysis found a 42% overestimation in the reported effect of Acceptance and Commitment Therapy (ACT) for depression.🧵 1/8

Up to 50% of research funding is wasted on irreproducible studies. Reproducibility is the cornerstone of trustworthy science. Here are 4 essential practices that help make research more reproducible. 1/6

Getting started on ResearchHub just got easier. Explore the new landing page 👇

$600,000 raised on ResearchHub to empower scientists worldwide.

How safe is your tap water? Adam Draper is funding an independent study to find out. With up to $100,000 we’re looking for researchers with expertise in environmental science, public health, urban infrastructure, or data analytics to test water in major U.S. cities or top campuses... 1/3

Update from our partnership with the Center for Open Science — @cos.io‬: 3 preprints have now been fully evaluated and published in the Lifecycle Journal. ResearchHub led the open peer review process, delivering: ✅ Public scores ✅ Open peer reviews ✅ Fast turnaround (9.5 days on average)

What’s trending on ResearchHub right now?

You can find $150 peer review bounties by filtering the 'Earn' tab for your areas of expertise.

You can earn $150 for peer reviewing on ResearchHub. 🧵 1/7

You can earn $150 for peer reviewing on ResearchHub. 🧵 1/7

ResearchHub is an open-source community dedicated to accelerating scientific research. We encourage anyone motivated by our mission to build alongside us. Check out our public GitHub Kanban board to see what we're working on and where you can contribute.

Resurrecting Ancient DNA Iowa State assistant professor @swnisu.bsky.social‬ is using AI to resurrect ancient enzymes, and he’s posting live updates on ResearchHub, as it happens. 1/7

Prof. S. Jong Kon Chin from UCL traced the rise of biotech in SF. His findings challenge a core belief in R&D industries: Firms that openly shared valuable research findings saw higher R&D productivity than those that kept results proprietary. Here’s why openness wins 🧵 1/9

"The truth will bubble to the top, that's the beauty of science."