🧬 New funding opportunity now open on @ResearchHub: Next-Gen Human Enhancement — Muscle, Cognition, and Mood. 💰$10,000 in seed funding for the best preregistered proposal. Open to PhD students, postdocs, and faculty worldwide.

If affiliated with a registered 501(c)(3) nonprofit, funding research through ResearchHub can qualify as tax-deductible. Most U.S. universities and research institutions fall under this category. ✅ Good for science ✅ Good for your taxes

𝗖𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆 𝗨𝗽𝗱𝗮𝘁𝗲𝘀 | 𝗤𝟭, 𝟮𝟬𝟮𝟲 → New Hires → Product Updates → $400k+ in Funding Opportunities → ResearchCoin Listed on @coinbase UK ...and more! Here's everything that landed in Q1 2026:

Fund research through ResearchHub in 4 simple steps: researchhub.com/fund

Preprints accelerate science by making new research available immediately - not after months or years of peer review. The tradeoff: without peer review, it's hard to trust that the studies were done rigorously...

Here’s why science funders use ResearchHub: 1. Fund exactly what you care about 2. Funds go directly to researchers 3. Expert review before funding 4. Track outcomes in real time 5. Tax benefits

You can now buy or deposit ResearchCoin directly into your ResearchHub wallet. researchhub.com/researchcoin

Most AI models in biomedicine work in silos. Histology captures tissue structure. Spatial transcriptomics captures gene expression. But their representations are typically analyzed separately.

An application to our $10k Aging & Longevity RFP targets a quiet driver of aging: advanced glycation end products (AGEs). These sugar-derived molecules accumulate over time and contribute to cardiovascular disease, neurodegeneration, and diabetes.

AxonVoice, led by investigators at @axondao.bsky.social, proposes a $5k Phase I build to create a standardized, reproducible, AI-ready voice biomarker infrastructure. The goal: scalable, reliable phenotyping of neurological and psychological states for research and future clinical use.

Most aging clocks can measure biological age. But they don’t reveal which genes to target to slow it. A team from MIT, @ragoninstitute.bsky.social of @massgenbrigham.bsky.social, and @broadinstitute.org of @mit.edu and @harvard.edu applied to our Aging & Longevity RFP to address that gap.

Earn ResearchCoin for contributing to science on ResearchHub.

A research team applied to our Aging & Longevity RFP to test if gut proteins become less soluble as we age. They compare the small intestine and colon to determine if changes differ by region. If true, the findings could link immune metabolic remodeling to region-specific proteostasis instability.

You can convert your $RSC to cash (and vice versa) on supported exchanges.

Exercise is known to lower dementia risk. But how exactly? This preprint shows that aerobic activity may strengthen the brain’s smallest blood vessels. Making them more resilient during aging and early Alzheimer’s pathology.

Most fMRI studies rely on relatively small datasets, often just dozens or a few hundred people. This preprint introduces NeuroSTORM, a foundation model pretrained on 28.65 million fMRI frames, over 9,000 hours of scans from 50,000+ individuals.

Can an AI trained on regular photos learn to read medical scans? Researchers put DINOv2, trained on 142M natural images, to the test across 100+ experiments on X-rays, CT, and MRI. They asked it to detect disease and outline organs.

Exercise clearly improves health and longevity, but the molecular signals behind it are hard to measure. This recent study uses multi-platform plasma proteomics to track how proteins change after exercise and with long-term training.

Many drugs for bowel disease fail because they target the wrong cells in the human gut. To address this, researchers built an atlas of ~1 million human intestinal cells and used machine learning to identify the specific gene programs driving disease in each cell type.

You can now fund research or tip content on ResearchHub with a credit card.

In this new preprint, Basecamp Research in collaboration with NVIDIA Health introduce EDEN. EDEN is a foundation AI model that enables AI-Programmable Gene Insertion (aiPGI) by learning how gene insertion works across evolution.

At SciCon 2025, brianarmstrong.bsky.social shared bold predictions on AI’s role in driving future scientific breakthroughs.

Submit a research proposal. Get funded to carry it out. Apply for open Requests for Proposals (RFPs) on ResearchHub.

New Request for Proposals (RFP): AI for Drug Discovery CerebrumDAO has opened a new RFP to fund early-stage research using AI for drug discovery, with a focus on neurodegenerative disorders. 💵 Funding: $5,000 🗓 Deadline: Feb 27, 2026

Most people only associate microglia with brain inflammation and disease. This study shows that cortical microglia also play a role in maintaining sleep-wake balance, by supporting noradrenergic signaling that maintains wakefulness in the healthy brain.

"Motivated reasoning in sustainable consumption: A partisan environmental framing experiment", a Research Plan published in Lifecycle Journal, is under review with @researchhubf.bsky.social. Check it out if you'd like to be part of the evaluation process! www.researchhub.com/paper/105997... @cos.io

"Consciousness and emotions in non-human animals: Are laypeople more or less skeptical than experts?", a Research Plan in @cos.io Lifecycle Journal, is under review at @researchhubf.bsky.social. You can be part of the evlauation process, bounty closes in 3 days: www.researchhub.com/paper/105979...

Lifecycle Journal pub "Reversal or no reversal, that is the question – A conceptual replication of cross-cultural spatial-numerical associations" is under review at @researchhubf.bsky.social 2 days left on the bounty if you want to be part of the evaluation! www.researchhub.com/paper/105961...

We’ve opened 5 new Requests for Proposals to fund research across key areas in biomedicine. Open RFPs: • AI Tools & AI Agents in Biomedical Research — $5k • Genomics & Proteomics — $5k • Aging & Longevity — $10k • Vascular Biology — $10k • Neuroscience — $10k 🗓 Deadline: Feb 15, 2026

Anyone can fund, govern, and support science on ResearchHub with ResearchCoin.

HIV has been incurable for over 40 years. New research suggests this may no longer be the case. Scientists found that rejuvenating CD4 T cells can eliminate hidden HIV reservoirs, pointing toward a possible functional cure without lifelong treatment.

Leading funders discuss where science is headed in the next ten years as it becomes open and AI-driven.

~30% of IVF cycles fail even with healthy embryos. Researchers recreated implantation in the lab using patient-derived uterine organoids and stem cell blastoids. By measuring hormone release and invasion, they showed that IVF success can be predicted by directly testing how the uterus behaves.

Connect with our community supporting ResearchHub in building the future of science, powered by $RSC. Join the ResearchHub community on Discord. 🔗 discord.gg/researchhub

Humans eat small, frequent meals (1-2% body weight). But Burmese pythons can fast for months and then eat their entire body weight in one sitting. By studying what happens after these extreme meals, researchers identify a gut-derived molecule that signals the brain to reduce appetite.

Millions of papers are published every year, yet only a small fraction translate into products and services people actually benefit from.

Scientists share what it’s like to get funded through preregistrations on ResearchHub. ✅ Paid, constructive peer review ✅ Open and faster funding

📹 @itchdoctor shares why negative results and failed trials are some of the most valuable data in science.

ResearchHub Wrapped 2025.

A team of 28 researchers, including @fabiantheis.bsky.social, built the first single-cell map of how human immune cells respond to cytokines. It provides a reference for decoding immune signaling in health and disease and for guiding therapeutic discovery.

We're realigning financial incentives in science with crypto (ResearchCoin).

SciCon 2025 was an invite-only, full day of dialogue on open science, publishing, and research funding. Watch the full day or jump straight to what matters most to you. 👇 youtube.com/playlist?li...

ResearchHub co-founders Brian Armstrong and Patrick Joyce discuss the core problems in science today and and what real progress should look like. Watch the full conversation 👇 youtu.be/is1tzDZWJmY

How could we spotlight groundbreaking work that isn’t getting attention elsewhere?

A full day of discussions and networking left everyone energized and aligned on building better, faster and more open science. Thank you to everyone who joined us for SciCon 2025. See you at the next edition!

SciCon 2025 brought scientists, funders and founders together in one room for a full day of discussions. Here are the highlights from an event that left everyone energized. 1/8

We’re looking forward to a candid conversation with major science funders about how they allocate capital and measure impact. Speakers: • Jordan Dworkin, PhD | Coefficient Giving • Kumar Garg | Renaissance Philanthropy • Bishakha Mona, PhD | Science Philanthropy Alliance

Faster and more transparent science funding isn’t just theoretical, we’ve seen it work. We’re bringing researchers and funders together to discuss practical alternatives to traditional grants.

Can (and should) academia be decentralized? Our panel of experts will assess the feasibility of decentralization in academia and what it would mean for science.

We’re honored to announce Professor John Ioannidis will deliver a keynote at SciCon 2025. Dr. Ioannidis is Stanford professor and one of the most-cited scientists. He has delivered ~700 invited and honorary lectures and is globally recognized as a leading voice in reproducibility and meta-research.