@citizenphage.bsky.social
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reposted by
PhageExe
4 months ago
If you want to improve promiscuity and yield of Pseudomonas aeruginosa for production of phages, start by taking out its restriction modification system:
www.biorxiv.org/content/10.1...
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Eliminating the type I restriction endonuclease from Pseudomonas aeruginosa PAO1 for optimised phage isolation
Phage therapy is a promising treatment for multidrug-resistant bacterial infections. Due to their high host specificity, phages must be matched to the target clinical strains. Efficiently identifying ...
https://www.biorxiv.org/content/10.1101/2025.05.30.656992v1
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reposted by
Meaghan Castledine
6 months ago
Thank you for hosting
@nataliegreenpeer.bsky.social
and
@citizenphage.bsky.social
Great updates on global status of phage therapy and how to bring this into the UK. Feel very lucky to have had the chance to attend!
add a skeleton here at some point
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Great to see this work out by the Yale team!
add a skeleton here at some point
5 months ago
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Delivering phages to the site of infection by Trojan Horse. Cool idea to wrap infected cells in a soluble polyme, with timed release where they are needed.
www.nature.com/articles/s41...
#AMR
#phage
#biotech
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Enhancing phage therapy by coating single bacteriophage-infected bacteria with polymer to preserve phage vitality - Nature Biomedical Engineering
The wrapping of single bacteriophage-infected bacteria with a polymeric nanoscale coating preserves the vitality of the replicating phages, which led to enhanced therapeutic outcomes in mice with bact...
https://www.nature.com/articles/s41551-025-01354-3
7 months ago
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Big congratulations to invitris on securing EIC Accelerator funding! A huge win for their groundbreaking cell-free phage-based therapeutics! Excited to see this technology developing for host-independent, safe and effective phage therapeutics Read more:
www.bio-m.org/en/news/news...
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Invitris wins EIC Accelerator Funding – another success for the m<sup>4</sup> Award winner
Das Martinsrieder Start-up Invitris, Gewinner des von BioM koordinierten m4 Award, wurde in der neuesten Förderrunde des EIC Accelerator als eines von 71 Unternehmen ausgewählt. Das Biotech-Start-up ü...
https://www.bio-m.org/en/news/news-detail/invitris-wins-eic-accelerator-funding-another-success-for-the-m4-award-winner.html
7 months ago
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On a day where the National Audit Office reported that the government was not doing enough to combat the threat of untreatable bacterial infections (
www.theguardian.com/society/2025...
), we met with legislators to highlight the power of phage therapy to provide new treatments to patients.
7 months ago
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reposted by
Natalie Bennett
7 months ago
Can you explode a bacteria with a phage? In Parliament until 1pm, committee room 4a, find out about
#phages
and their use in medicine with Exeter University. Particularly crucial in age of
#AMR
. Other nations racing ahead, we are being left behind
#PublicHealth
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