What do patients and caregivers really think about Alzheimer’s treatments? Drs. Catherine Auriemma & Carolyn Chow share research that uncovers hopes, worries, and family goals in care. Hear more on the Expert Voices in Dementia podcast.

Judge Lois Murphy brings the courtroom perspective to elder justice. Hear her stories on guardianship, family dynamics, and protecting autonomy in our new episode of The Age of Aging.

Be part of Penn Memory Center community. From research updates to caregiving support and upcoming events, follow along and stay informed. 📍Find us on Instagram, Facebook, YouTube, LinkedIn, and Bluesky

Elder law is about preserving dignity and autonomy. In our new episode of The Age of Aging, Charlie Sabatino shares lessons from 37 years with the ABA Commission on Law and Aging. 🎧 Tune in here: bit.ly/4mgE94s

High blood pressure often shows no symptoms, but raises risk of stroke, heart disease, kidney damage, and dementia. New American Heart Association guidelines: treat it early with diet & exercise. “If you catch it early, you can gain many more years of healthy life,” says Penn’s Dr. Jordana Cohen.

Registration is now open for the 2025 Penn FTD Center’s Annual Caregiver Conference! 📆 Monday, November 3, 2025 ⏱ 8am-4:30pm 📍Smilow Center for Translational Research Click the link in our bio for the link to register for the conference! We hope to see you in November!

What does justice look like for older adults? Too often, seniors face stigma, exploitation, and little support. Season 4 of The Age of Aging opens with 3 leading voices on elder justice, unpacking the legal, cultural, and systemic challenges and how to build a more just future.

Air pollution doesn’t just harm our lungs, it may also harm our brains. New research led by Dr. Edward Lee, co-director of Penn Institute on Aging, finds people with Alzheimer’s living in high-pollution areas face faster memory loss, impaired judgment, and more daily challenges.

Who’s pushing the boundaries of Alzheimer’s research? What breakthroughs are shaping the future? Get the inside story in inSight, the Penn Memory Center’s biweekly newsletter. Sign up for updates on science, care, and hope: bit.ly/PMC-InSight

“The POINTER study shows lifestyle choices like exercise, diet, and social connection can boost brain health.” – Dr. Jason Karlawish Hear more takeaways from AAIC 2025 in our bonus Age of Aging episode. ▶️ Watch the full episode ✅ Subscribe today so you don’t miss Season 4 coming soon

In our bonus episode of The Age of Aging, Penn Memory Center Co-Director Dr. David Wolk reflects on the momentum in Alzheimer’s research, from blood biomarkers to new therapies that are already shaping care. Listen here: bit.ly/3Jz6W6K

At #AAIC25, PMC Co-Director Dr. Jason Karlawish called out a paradox: “Spectacular progress… but a policy infrastructure that is unscientific and hostile.” In a bonus episode of The Age of Aging, he reflects on funding cuts, biomarkers, and new therapies. 🎧 Listen here: bit.ly/3Jz6W6K

At #AAIC25, Dr. Christopher Brown shared early real-world results of lecanemab. Using personalized disease trajectories, his team found slowed decline after a year of treatment while also flagging nonresponders. Attendees called the data “remarkable.”

What will shape Alzheimer’s research in the year ahead? In a bonus episode of The Age of Aging, Penn Memory Center’s Dr. Jason Karlawish & Dr. David Wolk share insights from AAIC 2025 on funding, biomarkers, & breakthroughs already changing care.

"Take her home and love her." That was the advice Ellen Boyle’s parents received in 1965 when she was born with Down syndrome. It became the guiding light of her family’s journey, through decades of joy, advocacy, and eventually, Alzheimer’s. Read more in our Disability and Dementia Series.

Be part of Penn Memory Center community. From research updates to caregiving support and upcoming events, follow along and stay informed. 📍Find us on Instagram, Facebook, YouTube, LinkedIn, and Bluesky

Could we stop Alzheimer’s before it starts? New FDA-approved drugs like lecanemab and donanemab are giving researchers hope, not just to slow dementia, but to prevent it altogether. Clinical trials are underway to find out. Read more on where Alzheimer’s science stands and what might be coming next.

Who’s pushing the boundaries of Alzheimer’s research? What breakthroughs are shaping the future? Get the inside story in inSight, the Penn Memory Center’s biweekly newsletter. Sign up for updates on science, care, and hope: bit.ly/PMC-InSight

A good story can change how people see aging. The Age of Aging podcast brings those stories to life, and ratings and reviews help them reach the people who need them most. Take a minute to rate or review your favorite episode. 🔗 linktr.ee/The_Age_of_Aging

How should clinicians talk about a diagnosis of MCI or dementia? A new JAMA paper co-authored by PMC’s Dr. Jason Karlawish offers a framework grounded in empathy, shared decision-making, and support.

Could leaded gas be linked to memory loss decades later? A new study says yes: Older adults from high-lead areas (think leaded gasoline) are 20% more likely to report memory issues today. Even low exposure left neurons vulnerable, researchers found.

The FDA recently approved a safer way to give donanemab, a treatment that targets amyloid in the brain. This new approach lowers the risk of serious side effects, especially for people with a genetic risk factor called APOE4. Learn more: bit.ly/3Hkk6ni

In the Season 3 finale of The Age of Aging, Dr. Jason Karlawish, co-director of the Penn Memory Center, highlights the urgent need to better diagnose and understand Lewy Body Dementia (LBD). 🎙️ Full episode: bit.ly/4eY8L8K

Day 4 at #AAIC25 is packed with Penn-led insights on improving memory care, advancing AI in neuroimaging, and shaping inclusive research protocols. Here’s what our team is sharing today: Swipe through the full lineup. #PennatAAIC25

Day 3 at #AAIC25 shows how every piece of the puzzle matters, from students to established clinicians. Katrina Bazemore breaks down how gene-variant strategies impact Alzheimer’s risk scores. Dr. Sandhitsu Das explores how ARIA affects brain changes during anti-amyloid treatment. #PennatAAIC25

Congratulations to Dr. Christos Davatzikos, recipient of the 2025 de Leon Prize in Neuroimaging at #AAIC25! One of 10 researchers honored for his work in Alzheimer’s science, he was recognized for a top paper in neuroimaging of neurodegenerative disease. 🔗 bit.ly/472qKZK #PennatAAIC25

It’s day 2 of #AAIC25 and Penn researchers are leading conversations around biomarkers, brain imaging, digital tools, and data systems shaping the future of care and prevention. #PennatAAIC25

AAIC 2025 officially kicks off today, and Penn is showing up in full force. From biomarkers to global collaboration, our researchers are shaping the future of Alzheimer’s care. 👉 Follow #PennatAAIC25 for updates all week from Toronto.

AAIC 2025 is almost here and Penn is already on the ground! Today marks the pre-conference day of the Alzheimer’s Association International Conference, with many of our researchers sharing their latest findings. Follow along all week at #PennatAAIC25 as Penn experts present their work in Toronto.

“I tried to be strong. I thought I could do it alone. I broke.” In the season finale of the Age of Aging, caregiver Linda Szypula reflects on the emotional toll of caring for a loved one with Lewy Body Dementia, and the power of letting others in. 🎧 Listen now: bit.ly/4eY8L8K

All adults with Down syndrome develop Alzheimer’s pathology by age 40, yet were long excluded from trials. Dr. Michael Rafii is changing that, building a pipeline of inclusive research from biomarkers to global studies. Learn more about his work: bit.ly/46pljnv

Lewy Body Disease is the second most common cause of dementia, yet it’s often misdiagnosed and misunderstood. In our Season 3 finale, we spotlight this complex condition through film, caregiving stories, and expert insights from Penn Memory Center Co-Director Dr. Jason Karlawish. 🎧 bit.ly/4eY8L8K

“He wasn’t a burden to me. But I shouldn’t have had to fight so hard for someone I loved. That was the burden.” Mary’s brother Pete had Down syndrome. When he was diagnosed with Alzheimer’s, she became his care partner and advocate. Read the full story, part of our Disability and Dementia Series

What happens to intimacy when dementia enters a relationship? In the latest Age of Aging episode, Penn Memory Center Director of Social Work Alison Lynn opens up a quiet but common part of caregiving—and gives families permission to talk about it. 🎧 Listen now: bit.ly/3IlJ1Hb

“She went home to live with her family for another 10 years after it looked like she wasn’t going to live another day.” When medications failed, Dr. Brent Forester turned to electroconvulsive therapy for an Alzheimer’s patient with severe aggression. What happened next sparked a new clinical study.

In our latest episode, caregiver and author Lisa Marshall shares the deeply personal story of loving—and letting go of—physical intimacy with her husband, Peter, after his Alzheimer’s diagnosis. 🎧 Listen now → bit.ly/3IlJ1Hb 📘 Explore Lisa’s memoir Oh Hello Alzheimer's → bit.ly/4kDMMFC

Stay connected with Penn Memory Center! Whether you're looking for research updates, caregiver tips, or event announcements, we're just a follow away. 📍Find us on Instagram, Facebook, YouTube, LinkedIn, and Bluesky!

💬 “I felt like his wife again—not his caregiver.” In our most vulnerable episode yet, caregiver and author Lisa Marshall opens up about love, grief, and the moment she chose to say goodbye to physical intimacy—with tenderness and intention. Listen now: bit.ly/3IlJ1Hb

Learn more about the project by Dr. Kyra O'Brien and her team on a Warning Assessment and Alerting Tool for Cogntive Health (WATCH), one of our Year 4 awardees, here: youtu.be/sy77pszD2g0?...

“We need to move in the direction of oncology. Early detection matters.” Dr. Kyra O’Brien joined The Age of Aging to talk anti-amyloid therapies, new blood tests for Alzheimer’s, and why the GUIDE program could transform care for both patients and caregivers. 🎧 Listen now: bit.ly/408tb9d

After years of compassionate care, research, and mentorship at Penn Memory Center, Dr. Jeffrey Maneval is headed to MaineHealth to expand dementia care and research across rural Maine. His impact on patients, families, and future specialists will be long remembered.

Traveling this 4th of July with a loved one who has dementia? It can be done—with the right plan. Penn Memory Center Director of Social Work Alison Lynn offers guidance for caregivers on managing expectations, staying flexible, and putting support systems in place.

As Chief Medical Officer at Penn Medicine, Dr. PJ Brennan helped lead the health system through the COVID-19 crisis. In our latest episode, he reflects on what the pandemic revealed about how we care for older adults—and where we go from here. 🎧 Listen to the full episode: bit.ly/408tb9d

Bipolar disorder in older adults is more complex than many realize—and closely tied to dementia, depression, and aging. Dr. Brent Forester, a leader in geriatric psychiatry, is uncovering why bipolar disorder may raise the risk for Alzheimer’s and related dementias.

Bipolar disorder in older adults is more complex than many realize—and closely tied to dementia, depression, and aging. Dr. Brent Forester, a leader in geriatric psychiatry, is uncovering why bipolar disorder may raise the risk for Alzheimer’s and related dementias.

Formal help + family caregiving = better outcomes. Economist Norma Coe lived it and studied it—finding that combining both led to better mobility, less depression, and higher self-rated health. Read about her journey and research 👇

💡In this month’s Research Roundup, Postdoctoral Fellow Rory Boyle PhD outlines ways that researchers can study resistance and resilience to Alzheimer’s disease in people with Down syndrome. Read now at the link in our bio or by visiting our website!

The Healthcare system is changing. Will dementia care keep up? Dr. PJ Brennan and Dr. Kyra O’Brien talk dementia care, anti-amyloid therapies, and what the new GUIDE program means for patients and caregivers. 🎧 Tune in here: bit.ly/408tb9d

If you missed Dr. Walter Curioso's presentation on "AI for Strengthening Healthcare Systems in Low- and Middle-income Countries: A Perspective from Peru" you can watch the recording on our YouTube channel here: youtu.be/PkfK3Ffvvpg?...

“The story started with love.” After early-onset dementia changed their families, Diana Cose and Patty LaFleur built Lorenzo's House—a lifeline for young caregivers. From peer matches to youth support groups, they’re reshaping dementia care. 🎧 Listen now: bit.ly/3Zr2VGC