Machine Learning in Biomedicine (@mlbiomed.bsky.social)

Excited to share our latest pre-print on profiling DNA adducts with nanopore sequencing! This study was led by Yrjö Koski, who developed a computational toolkit called IonStats, and identified several compound-specific effects caused by genotoxic compounds. www.biorxiv.org/content/10.1...

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Compound-specific DNA adduct profiling with nanopore sequencing and IonStats Covalently bound DNA adducts are mutation precursors that contribute to aging and diseases such as cancer. Accurate detection of adducts in the genome will shed light on tumorigenesis. Commonly used a... https://www.biorxiv.org/content/10.1101/2025.10.31.685820v1