@jakecrouse.bsky.social
📤 109
📥 587
📝 5
reposted by
Department of Psychiatry, University of Oxford
about 2 months ago
📢 NEW RESEARCH: Why do some people respond to one antidepressant medication and not another? A new paper used prescription data & genetic information from 12,000+ participants to test whether genetic differences distinguish patterns of antidepressant prescribing 👇
jamanetwork.com/journals/jam...
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Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder
This cohort study evaluates phenotypic and genetic heterogeneity in major depressive disorder.
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2844334
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reposted by
JAMA Psychiatry
about 2 months ago
Among adults with #Depression, complex antidepressant treatment patterns were associated with higher polygenic risk for psychiatric traits but not with sustained use of a single antidepressant.
ja.ma/4k3LpkN
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New in
@jamapsychiatry.com
- in the Australian Genetics of Depression Study we show using 4.5 yrs of prescription data that genetic risk for ADHD, depression, neuroticism and bipolar disorder influence the complexity of an individual's depression treatment journey
jamanetwork.com/journals/jam...
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Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder
This cohort study evaluates phenotypic and genetic heterogeneity in major depressive disorder.
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2844334
about 2 months ago
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reposted by
Our new paper in Biological Psychiatry
#SOBP
in 3,000 Australians with
#atypical
#depression
(N=15K) links atypicality with poorer response to SSRIs and SNRIs + genetic risk for
#metabolic
,
#inflammatory
, and
#circadian
traits.
www.biologicalpsychiatryjournal.com/article/S000...
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Atypical depression is associated with a distinct clinical, neurobiological, treatment response and polygenic risk profile
Atypical depression is considered a distinct clinical subtype of major depression, yet its predictive validity and clinical utility remain contested. We investigated association between atypical depre...
https://www.biologicalpsychiatryjournal.com/article/S0006-3223(26)00004-1/fulltext
about 2 months ago
0
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Our new paper in Biological Psychiatry
#SOBP
in 3,000 Australians with
#atypical
#depression
(N=15K) links atypicality with poorer response to SSRIs and SNRIs + genetic risk for
#metabolic
,
#inflammatory
, and
#circadian
traits.
www.biologicalpsychiatryjournal.com/article/S000...
loading . . .
Atypical depression is associated with a distinct clinical, neurobiological, treatment response and polygenic risk profile
Atypical depression is considered a distinct clinical subtype of major depression, yet its predictive validity and clinical utility remain contested. We investigated association between atypical depre...
https://www.biologicalpsychiatryjournal.com/article/S0006-3223(26)00004-1/fulltext
about 2 months ago
0
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reposted by
More evidence linking
#depression
&
#daylight
🌞 In 13,000 Australians with depression, more time in daylight was associated with better sleep and mental health (adjusting for genetic risk, season, etc)
#sleep
#circadian
#mentalhealth
bit.ly/4ei9th5
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Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression | European Psychiatry | Cambridge Core
Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression - Volume 68 Issue 1
https://bit.ly/4ei9th5
9 months ago
0
4
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More evidence linking
#depression
&
#daylight
🌞 In 13,000 Australians with depression, more time in daylight was associated with better sleep and mental health (adjusting for genetic risk, season, etc)
#sleep
#circadian
#mentalhealth
bit.ly/4ei9th5
loading . . .
Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression | European Psychiatry | Cambridge Core
Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression - Volume 68 Issue 1
https://bit.ly/4ei9th5
9 months ago
0
4
2
reposted by
Grateful to have played a small part in this letter published in World Psychiatry We identify 9 challenges to advancing early intervention in
#bipolardisorders
and hope to galvanise action on these issues
onlinelibrary.wiley.com/doi/10.1002/...
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Views of international experts on challenges to early intervention for bipolar disorder
Click on the article title to read more.
https://onlinelibrary.wiley.com/doi/10.1002/wps.21324
10 months ago
0
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Grateful to have played a small part in this letter published in World Psychiatry We identify 9 challenges to advancing early intervention in
#bipolardisorders
and hope to galvanise action on these issues
onlinelibrary.wiley.com/doi/10.1002/...
loading . . .
Views of international experts on challenges to early intervention for bipolar disorder
Click on the article title to read more.
https://onlinelibrary.wiley.com/doi/10.1002/wps.21324
10 months ago
0
3
1
reposted by
Wearables can detect skin temperature dysrhythmias in young people with mood disorders 🌡️
@brainandmindcentre.bsky.social
@ucsandiego.bsky.social
@isbd4.bsky.social
@smhr.org.au
@circadianmhnetw.bsky.social
journals.sagepub.com/doi/10.1177/...
#circadian
#bipolardisorder
#depression
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Twenty-four-hour Skin Temperature Rhythms in Young People With Emerging Mood Disorders: Relationships With Illness Subtypes and Clinical Stage - Mirim Shin, Joanne S. Carpenter, Shin H. Park, Connie J...
While circadian disruptions are common in some sub-groups of youth with mood disorders, skin temperature rhythms in these cohorts are understudied. We examined ...
https://journals.sagepub.com/doi/10.1177/07487304251328501?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
11 months ago
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Wearables can detect skin temperature dysrhythmias in young people with mood disorders 🌡️
@brainandmindcentre.bsky.social
@ucsandiego.bsky.social
@isbd4.bsky.social
@smhr.org.au
@circadianmhnetw.bsky.social
journals.sagepub.com/doi/10.1177/...
#circadian
#bipolardisorder
#depression
loading . . .
Twenty-four-hour Skin Temperature Rhythms in Young People With Emerging Mood Disorders: Relationships With Illness Subtypes and Clinical Stage - Mirim Shin, Joanne S. Carpenter, Shin H. Park, Connie J...
While circadian disruptions are common in some sub-groups of youth with mood disorders, skin temperature rhythms in these cohorts are understudied. We examined ...
https://journals.sagepub.com/doi/10.1177/07487304251328501?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
11 months ago
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