Simon Aubé
@simonaube.bsky.social
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PhD student in the Landry lab at Université Laval. Evolution and hockey analytics enthusiast. He/him
reposted by
Simon Aubé
EMBO Reports
about 1 month ago
A new review on
#evolution
is online! Pavithra Venkataraman and Christian Landry
@christianlandry.bsky.social
discuss a conceptual framework for the joint influence of coding and regulatory mutations in shaping fitness and impacting molecular
#evolution
. ->
link.springer.com/article/10.1...
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Molecular evolution in light of regulatory-coding epistasis - EMBO Reports
Predicting the fitness effects of mutations is central to understanding molecular evolution and interpreting genome sequence data. Such predictions remain challenging due to the inter-dependent roles ...
https://link.springer.com/article/10.1038/s44319-026-00821-5
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reposted by
Simon Aubé
Soham Dibyachintan
about 1 year ago
How does cryptic genetic variation influence the long-term fate of gene duplicates (paralogs)? Our new study addresses this question by dissecting the evolutionary potential of redundant myosin paralogs in yeast
nature.com/articles/s41...
(1/12)
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Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network - Nature Communications
Over time, paralogous genes accumulate changes in their sequences that do not affect their function, which is called cryptic variation. Using paralogous myosins, this study shows how cryptic variation...
https://nature.com/articles/s41467-025-56597-0
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