🚨Proud to share the preprint from my postdoc in Yves Gaudin’s lab, in collab with Frédéric Rieux-Laucat’s lab. 🧠Our key finding?
 NAP1 plays a dual role in regulating innate immunity. 📌This work highlights how phase separation modulates antiviral responses and explains some interferonopathies. 🔗⬇️

NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates https://www.biorxiv.org/content/10.1101/2025.05.21.655319v1

Ces recherches ont notamment impliqué des scientifiques de l'Institut de biologie intégrative de la cellule (@i2bcparissaclay.bsky.social - @cea.fr / @cnrs.fr / @univparissaclay.bsky.social / @inrae-france.bsky.social / @inserm.fr), situé à Gif-sur-Yvette (Essonne). @cnrsbiologie.bsky.social