Angela Getz (@angela-getz.bsky.social)

Synapse-specific and plasticity-regulated AMPA receptor mobility tunes synaptic integration Short-term plasticity (STP) filters synaptic inputs across rapid timescales. Nowacka et al. show that postsynaptic AMPAR desensitization and diffusion-trapping, shaped by auxiliary subunits and activity-dependent signaling, generate synapse-specific gain control. By broadening temporal filtering and adjusting short-term depression, receptor mobility emerges as a central regulator of circuit information processing. http://dlvr.it/TQm6W8